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IFIT1 (interferon induced protein with tetratricopeptide repeats 1)

Identity

Alias_namesG10P1
IFI56
IFNAI1
interferon-induced protein with tetratricopeptide repeats 1
Alias_symbol (synonym)GARG-16
Other aliasC56
IFI-56
IFI-56K
IFIT-1
ISG56
P56
RNM561
HGNC (Hugo) IFIT1
LocusID (NCBI) 3434
Atlas_Id 52498
Location 10q23.31  [Link to chromosome band 10q23]
Location_base_pair Starts at 89392546 and ends at 89406487 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FYTTD1 (3q29) / IFIT1 (10q23.31)FYTTD1 3q29 / IFIT1 10q23.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFIT1   5407
Cards
Entrez_Gene (NCBI)IFIT1  3434  interferon induced protein with tetratricopeptide repeats 1
AliasesC56; G10P1; IFI-56; IFI-56K; 
IFI56; IFIT-1; IFNAI1; ISG56; P56; RNM561
GeneCards (Weizmann)IFIT1
Ensembl hg19 (Hinxton)ENSG00000185745 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185745 [Gene_View]  chr10:89392546-89406487 [Contig_View]  IFIT1 [Vega]
ICGC DataPortalENSG00000185745
TCGA cBioPortalIFIT1
AceView (NCBI)IFIT1
Genatlas (Paris)IFIT1
WikiGenes3434
SOURCE (Princeton)IFIT1
Genetics Home Reference (NIH)IFIT1
Genomic and cartography
GoldenPath hg38 (UCSC)IFIT1  -     chr10:89392546-89406487 +  10q23.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFIT1  -     10q23.31   [Description]    (hg19-Feb_2009)
EnsemblIFIT1 - 10q23.31 [CytoView hg19]  IFIT1 - 10q23.31 [CytoView hg38]
Mapping of homologs : NCBIIFIT1 [Mapview hg19]  IFIT1 [Mapview hg38]
OMIM147690   
Gene and transcription
Genbank (Entrez)AK092813 AK308688 AK314588 AL548182 AL711085
RefSeq transcript (Entrez)NM_001270927 NM_001270928 NM_001270929 NM_001270930 NM_001548
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFIT1
Cluster EST : UnigeneHs.20315 [ NCBI ]
CGAP (NCI)Hs.20315
Alternative Splicing GalleryENSG00000185745
Gene ExpressionIFIT1 [ NCBI-GEO ]   IFIT1 [ EBI - ARRAY_EXPRESS ]   IFIT1 [ SEEK ]   IFIT1 [ MEM ]
Gene Expression Viewer (FireBrowse)IFIT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3434
GTEX Portal (Tissue expression)IFIT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09914   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09914  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09914
Splice isoforms : SwissVarP09914
PhosPhoSitePlusP09914
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)Interferon-induced_IFIT1    TPR-contain_dom    TPR-like_helical_dom    TPR_repeat   
Domain families : Pfam (Sanger)TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam13181   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)IFIT1
DMDM Disease mutations3434
Blocks (Seattle)IFIT1
PDB (SRS)4HOU   
PDB (PDBSum)4HOU   
PDB (IMB)4HOU   
PDB (RSDB)4HOU   
Structural Biology KnowledgeBase4HOU   
SCOP (Structural Classification of Proteins)4HOU   
CATH (Classification of proteins structures)4HOU   
SuperfamilyP09914
Human Protein AtlasENSG00000185745
Peptide AtlasP09914
HPRD00983
IPIIPI00018300   IPI01012302   
Protein Interaction databases
DIP (DOE-UCLA)P09914
IntAct (EBI)P09914
FunCoupENSG00000185745
BioGRIDIFIT1
STRING (EMBL)IFIT1
ZODIACIFIT1
Ontologies - Pathways
QuickGOP09914
Ontology : AmiGORNA binding  protein binding  cytoplasm  cytosol  cytosol  response to virus  response to virus  intracellular transport of viral protein in host cell  negative regulation of protein binding  host cell  positive regulation of viral genome replication  negative regulation of viral genome replication  negative regulation of defense response to virus by host  negative regulation of helicase activity  defense response to virus  type I interferon signaling pathway  cellular response to type I interferon  cellular response to exogenous dsRNA  
Ontology : EGO-EBIRNA binding  protein binding  cytoplasm  cytosol  cytosol  response to virus  response to virus  intracellular transport of viral protein in host cell  negative regulation of protein binding  host cell  positive regulation of viral genome replication  negative regulation of viral genome replication  negative regulation of defense response to virus by host  negative regulation of helicase activity  defense response to virus  type I interferon signaling pathway  cellular response to type I interferon  cellular response to exogenous dsRNA  
Pathways : KEGGHepatitis C    Herpes simplex infection   
NDEx NetworkIFIT1
Atlas of Cancer Signalling NetworkIFIT1
Wikipedia pathwaysIFIT1
Orthology - Evolution
OrthoDB3434
GeneTree (enSembl)ENSG00000185745
Phylogenetic Trees/Animal Genes : TreeFamIFIT1
HOVERGENP09914
HOGENOMP09914
Homologs : HomoloGeneIFIT1
Homology/Alignments : Family Browser (UCSC)IFIT1
Gene fusions - Rearrangements
Fusion : MitelmanFYTTD1/IFIT1 [3q29/10q23.31]  [t(3;10)(q29;q23)]  
Fusion: TCGAFYTTD1 3q29 IFIT1 10q23.31 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFIT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFIT1
dbVarIFIT1
ClinVarIFIT1
1000_GenomesIFIT1 
Exome Variant ServerIFIT1
ExAC (Exome Aggregation Consortium)IFIT1 (select the gene name)
Genetic variants : HAPMAP3434
Genomic Variants (DGV)IFIT1 [DGVbeta]
DECIPHERIFIT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFIT1 
Mutations
ICGC Data PortalIFIT1 
TCGA Data PortalIFIT1 
Broad Tumor PortalIFIT1
OASIS PortalIFIT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFIT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFIT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Pharmacogenomics of Infectious Diseases (PGx_IfD )
BioMutasearch IFIT1
DgiDB (Drug Gene Interaction Database)IFIT1
DoCM (Curated mutations)IFIT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFIT1 (select a term)
intoGenIFIT1
Cancer3DIFIT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147690   
Orphanet
MedgenIFIT1
Genetic Testing Registry IFIT1
NextProtP09914 [Medical]
TSGene3434
GENETestsIFIT1
Target ValidationIFIT1
Huge Navigator IFIT1 [HugePedia]
snp3D : Map Gene to Disease3434
BioCentury BCIQIFIT1
ClinGenIFIT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3434
Chemical/Pharm GKB GenePA29648
Clinical trialIFIT1
Miscellaneous
canSAR (ICR)IFIT1 (select the gene name)
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFIT1
EVEXIFIT1
GoPubMedIFIT1
iHOPIFIT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:37:55 CEST 2017

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