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IFNK (interferon kappa)

Identity

Alias_namesinterferon
Other aliasIFNT1
INFE1
HGNC (Hugo) IFNK
LocusID (NCBI) 56832
Atlas_Id 51313
Location 9p21.2  [Link to chromosome band 9p21]
Location_base_pair Starts at 27524314 and ends at 27526498 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ALDH3A2 (17p11.2) / IFNK (9p21.2)ALDH3A2 17p11.2 / IFNK 9p21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFNK   21714
Cards
Entrez_Gene (NCBI)IFNK  56832  interferon kappa
AliasesIFNT1; INFE1
GeneCards (Weizmann)IFNK
Ensembl hg19 (Hinxton)ENSG00000147896 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147896 [Gene_View]  chr9:27524314-27526498 [Contig_View]  IFNK [Vega]
ICGC DataPortalENSG00000147896
TCGA cBioPortalIFNK
AceView (NCBI)IFNK
Genatlas (Paris)IFNK
WikiGenes56832
SOURCE (Princeton)IFNK
Genetics Home Reference (NIH)IFNK
Genomic and cartography
GoldenPath hg38 (UCSC)IFNK  -     chr9:27524314-27526498 +  9p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFNK  -     9p21.2   [Description]    (hg19-Feb_2009)
EnsemblIFNK - 9p21.2 [CytoView hg19]  IFNK - 9p21.2 [CytoView hg38]
Mapping of homologs : NCBIIFNK [Mapview hg19]  IFNK [Mapview hg38]
OMIM615326   
Gene and transcription
Genbank (Entrez)AF146759 AF315688 AY358855 BC140280 BC141647
RefSeq transcript (Entrez)NM_020124
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFNK
Cluster EST : UnigeneHs.591083 [ NCBI ]
CGAP (NCI)Hs.591083
Alternative Splicing GalleryENSG00000147896
Gene ExpressionIFNK [ NCBI-GEO ]   IFNK [ EBI - ARRAY_EXPRESS ]   IFNK [ SEEK ]   IFNK [ MEM ]
Gene Expression Viewer (FireBrowse)IFNK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56832
GTEX Portal (Tissue expression)IFNK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P0W0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P0W0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P0W0
Splice isoforms : SwissVarQ9P0W0
PhosPhoSitePlusQ9P0W0
Domaine pattern : Prosite (Expaxy)INTERFERON_A_B_D (PS00252)   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Interferon_alpha/beta/delta   
Domain families : Pfam (Sanger)Interferon (PF00143)   
Domain families : Pfam (NCBI)pfam00143   
Domain families : Smart (EMBL)IFabd (SM00076)  
Conserved Domain (NCBI)IFNK
DMDM Disease mutations56832
Blocks (Seattle)IFNK
SuperfamilyQ9P0W0
Human Protein AtlasENSG00000147896
Peptide AtlasQ9P0W0
HPRD17133
IPIIPI00015079   
Protein Interaction databases
DIP (DOE-UCLA)Q9P0W0
IntAct (EBI)Q9P0W0
FunCoupENSG00000147896
BioGRIDIFNK
STRING (EMBL)IFNK
ZODIACIFNK
Ontologies - Pathways
QuickGOQ9P0W0
Ontology : AmiGOadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  cytokine activity  type I interferon receptor binding  extracellular region  extracellular space  regulation of transcription, DNA-templated  humoral immune response  negative regulation of cell proliferation  response to virus  cytokine-mediated signaling pathway  natural killer cell activation  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  positive regulation of innate immune response  defense response to virus  
Ontology : EGO-EBIadaptive immune response  T cell activation involved in immune response  natural killer cell activation involved in immune response  cytokine activity  type I interferon receptor binding  extracellular region  extracellular space  regulation of transcription, DNA-templated  humoral immune response  negative regulation of cell proliferation  response to virus  cytokine-mediated signaling pathway  natural killer cell activation  B cell differentiation  positive regulation of peptidyl-serine phosphorylation of STAT protein  B cell proliferation  response to exogenous dsRNA  positive regulation of innate immune response  defense response to virus  
Pathways : KEGGCytokine-cytokine receptor interaction    RIG-I-like receptor signaling pathway    Jak-STAT signaling pathway   
NDEx NetworkIFNK
Atlas of Cancer Signalling NetworkIFNK
Wikipedia pathwaysIFNK
Orthology - Evolution
OrthoDB56832
GeneTree (enSembl)ENSG00000147896
Phylogenetic Trees/Animal Genes : TreeFamIFNK
HOVERGENQ9P0W0
HOGENOMQ9P0W0
Homologs : HomoloGeneIFNK
Homology/Alignments : Family Browser (UCSC)IFNK
Gene fusions - Rearrangements
Fusion : MitelmanALDH3A2/IFNK [17p11.2/9p21.2]  [t(9;17)(p21;p11)]  
Fusion: TCGAALDH3A2 17p11.2 IFNK 9p21.2 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFNK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFNK
dbVarIFNK
ClinVarIFNK
1000_GenomesIFNK 
Exome Variant ServerIFNK
ExAC (Exome Aggregation Consortium)IFNK (select the gene name)
Genetic variants : HAPMAP56832
Genomic Variants (DGV)IFNK [DGVbeta]
DECIPHERIFNK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFNK 
Mutations
ICGC Data PortalIFNK 
TCGA Data PortalIFNK 
Broad Tumor PortalIFNK
OASIS PortalIFNK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFNK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFNK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFNK
DgiDB (Drug Gene Interaction Database)IFNK
DoCM (Curated mutations)IFNK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFNK (select a term)
intoGenIFNK
Cancer3DIFNK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615326   
Orphanet
MedgenIFNK
Genetic Testing Registry IFNK
NextProtQ9P0W0 [Medical]
TSGene56832
GENETestsIFNK
Target ValidationIFNK
Huge Navigator IFNK [HugePedia]
snp3D : Map Gene to Disease56832
BioCentury BCIQIFNK
ClinGenIFNK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56832
Chemical/Pharm GKB GenePA134970126
Clinical trialIFNK
Miscellaneous
canSAR (ICR)IFNK (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFNK
EVEXIFNK
GoPubMedIFNK
iHOPIFNK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:38:01 CEST 2017

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