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IGFALS (insulin-like growth factor binding protein, acid labile subunit)

Identity

Other namesALS
HGNC (Hugo) IGFALS
LocusID (NCBI) 3483
Location 16p13.3
Location_base_pair Starts at 1840414 and ends at 1843734 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IGFALS   5468
Entrez_Gene (NCBI)IGFALS  3483  insulin-like growth factor binding protein, acid labile subunit
Cards
GeneCards (Weizmann)IGFALS
Ensembl (Hinxton)ENSG00000099769 [Gene_View]  chr16:1840414-1843734 [Contig_View]  IGFALS [Vega]
AceView (NCBI)IGFALS
Genatlas (Paris)IGFALS
SOURCE (Stanford)NM_001146006 NM_004970
Genomic and cartography
GoldenPath (UCSC)IGFALS  -  16p13.3   chr16:1840414-1843734 -  16p13.3   [Description]    (hg19-Feb_2009)
EnsemblIGFALS - 16p13.3 [CytoView]
Mapping of homologs : NCBIIGFALS [Mapview]
OMIM601489   
Gene and transcription
Genbank (Entrez)AK292182 AK303146 AK313198 AK315808 BC025681
RefSeq transcript (SRS)NM_001146006 NM_004970
RefSeq transcript (Entrez)NM_001146006 NM_004970
RefSeq genomic (SRS)AC_000148 NC_000016 NC_018927 NG_011778 NT_010393 NW_001838339 NW_004078085
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NG_011778 NT_010393 NW_001838339 NW_004078085
Consensus coding sequences : CCDS (NCBI)IGFALS
Cluster EST : UnigeneHs.839 [ SRS ] Hs.839 [ NCBI ]
CGAP (NCI)Hs.839
Alternative Splicing : Fast-db (Paris)GSHG0011525
Alternative Splicing GalleryENSG00000099769
Gene ExpressionIGFALS [ NCBI-GEO ]   IGFALS [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP35858 (SRS) P35858 (Uniprot)
NextProtP35858
With graphics : InterProP35858
Splice isoforms : SwissVarP35858(Swissvar)
Domaine pattern : Prosite (SRS)LRR (PS51450)   
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (SRS)Cys-rich_flank_reg_C    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR-contain_N   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR-contain_N   
Related proteins : CluSTrP35858
Domain families : Pfam (SRS)LRR_1 (PF00560)    LRRNT (PF01462)   
Domain families : Pfam (Sanger)LRR_1 (PF00560)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam00560    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
DMDM3483
Blocks (Seattle)P35858
Human Protein AtlasENSG00000099769
HPRD03290
IPIIPI00020996   IPI00925635   
Protein Interaction databases
DIP (DOE-UCLA)P35858
IntAct (EBI)P35858
FunCoupENSG00000099769
REACTOMEIGFALS
Protein Interaction Database3483
BioGRIDIGFALS
InParanoidP35858
Interologous Interaction database P35858
IntegromeDBIGFALS
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)IGFALS
SNP (GeneSNP Utah)IGFALS
SNP : HGBaseIGFALS
Genetic variants : HAPMAPIGFALS
Somatic Mutations in Cancer : COSMICIGFALS 
CONAN: Copy Number AnalysisIGFALS 
Mutations and Diseases : HGMDIGFALS
OMIM601489   
GENETests601489   
Disease Genetic AssociationIGFALS
Huge Navigator IGFALS [HugePedia]  IGFALS [HugeCancerGEM]
Genomic VariantsIGFALS  IGFALS [DGVbeta]
ClinVarIGFALS
snp3D : Map Gene to Disease3483
General knowledge
Homologs : HomoloGeneIGFALS
Homology/Alignments : Family Browser (UCSC)IGFALS
Phylogenetic Trees/Animal Genes : TreeFamIGFALS
Chemical/Protein Interactions : CTD3483
Chemical/Pharm GKB GenePA29702
Clinical trialIGFALS
Cancer Resource (Charite)ENSG00000099769
Ontology : AmiGOinsulin-like growth factor binding  extracellular region  extracellular region  extracellular space  nucleus  nucleolus  cell adhesion  signal transduction  cellular protein metabolic process  
Ontology : EGO-EBIinsulin-like growth factor binding  extracellular region  extracellular region  extracellular space  nucleus  nucleolus  cell adhesion  signal transduction  cellular protein metabolic process  
Pathways : BIOCARTAGhrelin: Regulation of Food Intake and Energy Homeostasis [Genes]   
Other databases
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
PubGeneIGFALS
iHOPIGFALS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 18:01:15 CEST 2013
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