IKZF3 (IKAROS family zinc finger 3)

2007-02-01  

Identity

HGNC
LOCATION
17q12
LOCUSID
ALIAS
AIO,AIOLOS,ZNFN1A3
FUSION GENES

Other Information

Locus ID:

NCBI: 22806
MIM: 606221
HGNC: 13178
Ensembl: ENSG00000161405

Variants:

dbSNP: 22806
ClinVar: 22806
TCGA: ENSG00000161405
COSMIC: IKZF3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161405ENST00000293068Q9UKT9
ENSG00000161405ENST00000346243Q9UKT9
ENSG00000161405ENST00000346872Q9UKT9
ENSG00000161405ENST00000348427A0A0C4DGN9
ENSG00000161405ENST00000350532Q9UKT9
ENSG00000161405ENST00000351680Q9UKT9
ENSG00000161405ENST00000377944Q9UKT9
ENSG00000161405ENST00000377945Q9UKT9
ENSG00000161405ENST00000377952Q9UKT9
ENSG00000161405ENST00000377958Q9UKT9
ENSG00000161405ENST00000394189Q9UKT9
ENSG00000161405ENST00000439016Q9UKT9
ENSG00000161405ENST00000439167Q9UKT9
ENSG00000161405ENST00000467757Q9UKT9
ENSG00000161405ENST00000535189Q9UKT9
ENSG00000161405ENST00000583368Q9UKT9
ENSG00000161405ENST00000623724Q9UKT9

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
224642532012Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.60
244060732014Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.47
248236372014Aiolos promotes anchorage independence by silencing p66Shc transcription in cancer cells.26
125743332003Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice.24
191245062009Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.22
189786782008Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.21
171171802006HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.16
176466742007Combinatorial effects of splice variants modulate function of Aiolos.16
250060122014Sequencing-based approach identified three new susceptibility loci for psoriasis.15
22626592201217q12-21 variants are associated with asthma and interact with active smoking in an adult population from the United Kingdom.13

Citation

Dessen P

IKZF3 (IKAROS family zinc finger 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46122/ikzf3