Atlas of Genetics and Cytogenetics in Oncology and Haematology

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INPP5J (inositol polyphosphate-5-phosphatase J)

Identity

Other namesINPP5
PIB5PA
PIPP
HGNC (Hugo) INPP5J
LocusID (NCBI) 27124
Location 22q12.2
Location_base_pair Starts at 31518961 and ends at 31530683 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)INPP5J   8956
Entrez_Gene (NCBI)INPP5J  27124  inositol polyphosphate-5-phosphatase J
Cards
GeneCards (Weizmann)INPP5J
Ensembl (Hinxton)ENSG00000185133 [Gene_View]  chr22:31518961-31530683 [Contig_View]  INPP5J [Vega]
AceView (NCBI)INPP5J
Genatlas (Paris)INPP5J
SOURCE (Stanford)NM_001002837 NM_014422
Genomic and cartography
GoldenPath (UCSC)INPP5J  -  22q12.2   chr22:31518961-31530683 +  22q12.2   [Description]    (hg19-Feb_2009)
EnsemblINPP5J - 22q12.2 [CytoView]
Mapping of homologs : NCBIINPP5J [Mapview]
OMIM606481   
Gene and transcription
Genbank (Entrez)AK092859 AK095944 AK126610 AK293992 AK308921
RefSeq transcript (SRS)NM_001002837 NM_014422
RefSeq transcript (Entrez)NM_001002837 NM_014422
RefSeq genomic (SRS)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004078112
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004078112
Consensus coding sequences : CCDS (NCBI)INPP5J
Cluster EST : UnigeneHs.517549 [ SRS ] Hs.517549 [ NCBI ]
CGAP (NCI)Hs.517549
Alternative Splicing : Fast-db (Paris)GSHG0019955
Alternative Splicing GalleryENSG00000185133
Gene ExpressionINPP5J [ NCBI-GEO ]   INPP5J [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15735 (SRS) Q15735 (Uniprot)
NextProtQ15735
With graphics : InterProQ15735
Splice isoforms : SwissVarQ15735(Swissvar)
Domains : Interpro (SRS)Endo/exonuclease/phosphatase    IPPc   
Domains : Interpro (EBI)Endo/exonuclease/phosphatase    IPPc   
Related proteins : CluSTrQ15735
Domain families : Pfam (SRS)Exo_endo_phos (PF03372)   
Domain families : Pfam (Sanger)Exo_endo_phos (PF03372)   
Domain families : Pfam (NCBI)pfam03372   
Domain families : Smart (EMBL)IPPc (SM00128)  
DMDM27124
Blocks (Seattle)Q15735
Human Protein AtlasENSG00000185133
HPRD07573
IPIIPI00242711   IPI00242712   IPI00445092   IPI00894005   IPI00894224   IPI00893848   IPI00893616   
Protein Interaction databases
DIP (DOE-UCLA)Q15735
IntAct (EBI)Q15735
FunCoupENSG00000185133
REACTOMEINPP5J
Protein Interaction Database27124
BioGRIDINPP5J
InParanoidQ15735
Interologous Interaction database Q15735
IntegromeDBINPP5J
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)INPP5J
SNP (GeneSNP Utah)INPP5J
SNP : HGBaseINPP5J
Genetic variants : HAPMAPINPP5J
Somatic Mutations in Cancer : COSMICINPP5J 
CONAN: Copy Number AnalysisINPP5J 
Mutations and Diseases : HGMDINPP5J
OMIM606481   
GENETests606481   
Disease Genetic AssociationINPP5J
Huge Navigator INPP5J [HugePedia]  INPP5J [HugeCancerGEM]
Genomic VariantsINPP5J  INPP5J [DGVbeta]
ClinVarINPP5J
snp3D : Map Gene to Disease27124
General knowledge
Homologs : HomoloGeneINPP5J
Homology/Alignments : Family Browser (UCSC)INPP5J
Phylogenetic Trees/Animal Genes : TreeFamINPP5J
Catalytic activity : Enzyme3.1.3.56 [ Enzyme-Expasy ]   3.1.3.56 [ Enzyme-SRS ]   3.1.3.56 [ IntEnz-EBI ]   3.1.3.56 [ BRENDA ]   3.1.3.56 [ KEGG ]   
Chemical/Protein Interactions : CTD27124
Chemical/Pharm GKB GenePA164720918
Clinical trialINPP5J
Cancer Resource (Charite)ENSG00000185133
Ontology : AmiGOruffle  inositol-polyphosphate 5-phosphatase activity  cytoplasm  cytosol  plasma membrane  phospholipid metabolic process  phosphatidylinositol biosynthetic process  negative regulation of neuron projection development  SH3 domain binding  growth cone  negative regulation of microtubule polymerization  negative regulation of peptidyl-serine phosphorylation  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity  dendritic shaft  inositol phosphate metabolic process  small molecule metabolic process  phosphatidylinositol dephosphorylation  inositol-1,4,5-trisphosphate 5-phosphatase activity  inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity  
Ontology : EGO-EBIruffle  inositol-polyphosphate 5-phosphatase activity  cytoplasm  cytosol  plasma membrane  phospholipid metabolic process  phosphatidylinositol biosynthetic process  negative regulation of neuron projection development  SH3 domain binding  growth cone  negative regulation of microtubule polymerization  negative regulation of peptidyl-serine phosphorylation  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity  dendritic shaft  inositol phosphate metabolic process  small molecule metabolic process  phosphatidylinositol dephosphorylation  inositol-1,4,5-trisphosphate 5-phosphatase activity  inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity  
Pathways : KEGGInositol phosphate metabolismPhosphatidylinositol signaling system
Other databases
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
PubGeneINPP5J
iHOPINPP5J
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:58:06 CEST 2013
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