Atlas of Genetics and Cytogenetics in Oncology and Haematology


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INPP5J (inositol polyphosphate-5-phosphatase J)

Identity

Other namesINPP5
PIB5PA
PIPP
HGNC (Hugo) INPP5J
LocusID (NCBI) 27124
Location 22q12.2
Location_base_pair Starts at 31518909 and ends at 31530683 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)INPP5J   8956
Cards
Entrez_Gene (NCBI)INPP5J  27124  inositol polyphosphate-5-phosphatase J
GeneCards (Weizmann)INPP5J
Ensembl (Hinxton)ENSG00000185133 [Gene_View]  chr22:31518909-31530683 [Contig_View]  INPP5J [Vega]
ICGC DataPortalENSG00000185133
cBioPortalINPP5J
AceView (NCBI)INPP5J
Genatlas (Paris)INPP5J
WikiGenes27124
SOURCE (Princeton)NM_001002837 NM_001284285 NM_001284286 NM_001284287 NM_001284288 NM_001284289 NM_014422
Genomic and cartography
GoldenPath (UCSC)INPP5J  -  22q12.2   chr22:31518909-31530683 +  22q12.2   [Description]    (hg19-Feb_2009)
EnsemblINPP5J - 22q12.2 [CytoView]
Mapping of homologs : NCBIINPP5J [Mapview]
OMIM606481   
Gene and transcription
Genbank (Entrez)AK092859 AK095944 AK126610 AK293992 AK308921
RefSeq transcript (Entrez)NM_001002837 NM_001284285 NM_001284286 NM_001284287 NM_001284288 NM_001284289 NM_014422
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004929430
Consensus coding sequences : CCDS (NCBI)INPP5J
Cluster EST : UnigeneHs.517549 [ NCBI ]
CGAP (NCI)Hs.517549
Alternative Splicing : Fast-db (Paris)GSHG0019955
Alternative Splicing GalleryENSG00000185133
Gene ExpressionINPP5J [ NCBI-GEO ]     INPP5J [ SEEK ]   INPP5J [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15735 (Uniprot)
NextProtQ15735  [Medical]
With graphics : InterProQ15735
Splice isoforms : SwissVarQ15735 (Swissvar)
Catalytic activity : Enzyme3.1.3.56 [ Enzyme-Expasy ]   3.1.3.563.1.3.56 [ IntEnz-EBI ]   3.1.3.56 [ BRENDA ]   3.1.3.56 [ KEGG ]   
Domains : Interpro (EBI)Endo/exonuclease/phosphatase [organisation]   IPPc [organisation]  
Related proteins : CluSTrQ15735
Domain families : Pfam (Sanger)Exo_endo_phos (PF03372)   
Domain families : Pfam (NCBI)pfam03372   
Domain families : Smart (EMBL)IPPc (SM00128)  
DMDM Disease mutations27124
Blocks (Seattle)Q15735
Human Protein AtlasENSG00000185133 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ15735
HPRD07573
IPIIPI00242711   IPI00242712   IPI00445092   IPI00894005   IPI00894224   IPI00893848   IPI00893616   
Protein Interaction databases
DIP (DOE-UCLA)Q15735
IntAct (EBI)Q15735
FunCoupENSG00000185133
BioGRIDINPP5J
InParanoidQ15735
Interologous Interaction database Q15735
IntegromeDBINPP5J
STRING (EMBL)INPP5J
Ontologies - Pathways
Ontology : AmiGOruffle  inositol-polyphosphate 5-phosphatase activity  cytoplasm  cytosol  plasma membrane  phospholipid metabolic process  phosphatidylinositol biosynthetic process  negative regulation of neuron projection development  SH3 domain binding  growth cone  negative regulation of microtubule polymerization  negative regulation of peptidyl-serine phosphorylation  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity  dendritic shaft  inositol phosphate metabolic process  small molecule metabolic process  phosphatidylinositol dephosphorylation  inositol-1,4,5-trisphosphate 5-phosphatase activity  inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity  
Ontology : EGO-EBIruffle  inositol-polyphosphate 5-phosphatase activity  cytoplasm  cytosol  plasma membrane  phospholipid metabolic process  phosphatidylinositol biosynthetic process  negative regulation of neuron projection development  SH3 domain binding  growth cone  negative regulation of microtubule polymerization  negative regulation of peptidyl-serine phosphorylation  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity  dendritic shaft  inositol phosphate metabolic process  small molecule metabolic process  phosphatidylinositol dephosphorylation  inositol-1,4,5-trisphosphate 5-phosphatase activity  inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity  
Pathways : KEGGInositol phosphate metabolism    Phosphatidylinositol signaling system   
Protein Interaction DatabaseINPP5J
Wikipedia pathwaysINPP5J
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)INPP5J
snp3D : Map Gene to Disease27124
SNP (GeneSNP Utah)INPP5J
SNP : HGBaseINPP5J
Genetic variants : HAPMAPINPP5J
Exome VariantINPP5J
1000_GenomesINPP5J 
ICGC programENSG00000185133 
Somatic Mutations in Cancer : COSMICINPP5J 
CONAN: Copy Number AnalysisINPP5J 
Mutations and Diseases : HGMDINPP5J
Genomic VariantsINPP5J  INPP5J [DGVbeta]
dbVarINPP5J
ClinVarINPP5J
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM606481   
MedgenINPP5J
GENETestsINPP5J
Disease Genetic AssociationINPP5J
Huge Navigator INPP5J [HugePedia]  INPP5J [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneINPP5J
Homology/Alignments : Family Browser (UCSC)INPP5J
Phylogenetic Trees/Animal Genes : TreeFamINPP5J
Chemical/Protein Interactions : CTD27124
Chemical/Pharm GKB GenePA164720918
Clinical trialINPP5J
Cancer Resource (Charite)ENSG00000185133
Other databases
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
CoreMineINPP5J
iHOPINPP5J
OncoSearchINPP5J
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 26 14:35:26 CEST 2014

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