Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

INPP5J (inositol polyphosphate-5-phosphatase J)

Identity

Alias_namesPIB5PA
phosphatidylinositol (4
Alias_symbol (synonym)INPP5
PIPP
HGNC (Hugo) INPP5J
LocusID (NCBI) 27124
Atlas_Id 43409
Location 22q12.2  [Link to chromosome band 22q12]
Location_base_pair Starts at 31518909 and ends at 31530683 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)INPP5J   8956
Cards
Entrez_Gene (NCBI)INPP5J  27124  inositol polyphosphate-5-phosphatase J
AliasesINPP5; PIB5PA; PIPP
GeneCards (Weizmann)INPP5J
Ensembl hg19 (Hinxton)ENSG00000185133 [Gene_View]  chr22:31518909-31530683 [Contig_View]  INPP5J [Vega]
Ensembl hg38 (Hinxton)ENSG00000185133 [Gene_View]  chr22:31518909-31530683 [Contig_View]  INPP5J [Vega]
ICGC DataPortalENSG00000185133
TCGA cBioPortalINPP5J
AceView (NCBI)INPP5J
Genatlas (Paris)INPP5J
WikiGenes27124
SOURCE (Princeton)INPP5J
Genetics Home Reference (NIH)INPP5J
Genomic and cartography
GoldenPath hg19 (UCSC)INPP5J  -     chr22:31518909-31530683 +  22q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)INPP5J  -     22q12.2   [Description]    (hg38-Dec_2013)
EnsemblINPP5J - 22q12.2 [CytoView hg19]  INPP5J - 22q12.2 [CytoView hg38]
Mapping of homologs : NCBIINPP5J [Mapview hg19]  INPP5J [Mapview hg38]
OMIM606481   
Gene and transcription
Genbank (Entrez)AK092859 AK095944 AK126610 AK293992 AK308921
RefSeq transcript (Entrez)NM_001002837 NM_001284285 NM_001284286 NM_001284287 NM_001284288 NM_001284289 NM_014422
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)INPP5J
Cluster EST : UnigeneHs.517549 [ NCBI ]
CGAP (NCI)Hs.517549
Alternative Splicing GalleryENSG00000185133
Gene ExpressionINPP5J [ NCBI-GEO ]   INPP5J [ EBI - ARRAY_EXPRESS ]   INPP5J [ SEEK ]   INPP5J [ MEM ]
Gene Expression Viewer (FireBrowse)INPP5J [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27124
GTEX Portal (Tissue expression)INPP5J
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15735   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15735  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15735
Splice isoforms : SwissVarQ15735
Catalytic activity : Enzyme3.1.3.56 [ Enzyme-Expasy ]   3.1.3.563.1.3.56 [ IntEnz-EBI ]   3.1.3.56 [ BRENDA ]   3.1.3.56 [ KEGG ]   
PhosPhoSitePlusQ15735
Domains : Interpro (EBI)Endo/exonuclease/phosphatase    IPPc   
Domain families : Pfam (Sanger)Exo_endo_phos (PF03372)   
Domain families : Pfam (NCBI)pfam03372   
Domain families : Smart (EMBL)IPPc (SM00128)  
Conserved Domain (NCBI)INPP5J
DMDM Disease mutations27124
Blocks (Seattle)INPP5J
SuperfamilyQ15735
Human Protein AtlasENSG00000185133
Peptide AtlasQ15735
HPRD07573
IPIIPI00242711   IPI00242712   IPI00445092   IPI00894005   IPI00894224   IPI00893848   IPI00893616   
Protein Interaction databases
DIP (DOE-UCLA)Q15735
IntAct (EBI)Q15735
FunCoupENSG00000185133
BioGRIDINPP5J
STRING (EMBL)INPP5J
ZODIACINPP5J
Ontologies - Pathways
QuickGOQ15735
Ontology : AmiGOruffle  phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity  inositol-polyphosphate 5-phosphatase activity  protein binding  cytoplasm  cytosol  plasma membrane  phosphatidylinositol biosynthetic process  negative regulation of neuron projection development  SH3 domain binding  growth cone  negative regulation of microtubule polymerization  negative regulation of peptidyl-serine phosphorylation  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity  dendritic shaft  inositol phosphate metabolic process  phosphatidylinositol dephosphorylation  inositol-1,4,5-trisphosphate 5-phosphatase activity  inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity  
Ontology : EGO-EBIruffle  phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity  inositol-polyphosphate 5-phosphatase activity  protein binding  cytoplasm  cytosol  plasma membrane  phosphatidylinositol biosynthetic process  negative regulation of neuron projection development  SH3 domain binding  growth cone  negative regulation of microtubule polymerization  negative regulation of peptidyl-serine phosphorylation  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity  dendritic shaft  inositol phosphate metabolic process  phosphatidylinositol dephosphorylation  inositol-1,4,5-trisphosphate 5-phosphatase activity  inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity  
Pathways : KEGGInositol phosphate metabolism    Phosphatidylinositol signaling system   
NDEx NetworkINPP5J
Atlas of Cancer Signalling NetworkINPP5J
Wikipedia pathwaysINPP5J
Orthology - Evolution
OrthoDB27124
GeneTree (enSembl)ENSG00000185133
Phylogenetic Trees/Animal Genes : TreeFamINPP5J
HOVERGENQ15735
HOGENOMQ15735
Homologs : HomoloGeneINPP5J
Homology/Alignments : Family Browser (UCSC)INPP5J
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerINPP5J [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)INPP5J
dbVarINPP5J
ClinVarINPP5J
1000_GenomesINPP5J 
Exome Variant ServerINPP5J
ExAC (Exome Aggregation Consortium)INPP5J (select the gene name)
Genetic variants : HAPMAP27124
Genomic Variants (DGV)INPP5J [DGVbeta]
DECIPHER (Syndromes)22:31518909-31530683  ENSG00000185133
CONAN: Copy Number AnalysisINPP5J 
Mutations
ICGC Data PortalINPP5J 
TCGA Data PortalINPP5J 
Broad Tumor PortalINPP5J
OASIS PortalINPP5J [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICINPP5J  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDINPP5J
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch INPP5J
DgiDB (Drug Gene Interaction Database)INPP5J
DoCM (Curated mutations)INPP5J (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)INPP5J (select a term)
intoGenINPP5J
Cancer3DINPP5J(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606481   
Orphanet
MedgenINPP5J
Genetic Testing Registry INPP5J
NextProtQ15735 [Medical]
TSGene27124
GENETestsINPP5J
Huge Navigator INPP5J [HugePedia]
snp3D : Map Gene to Disease27124
BioCentury BCIQINPP5J
ClinGenINPP5J
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27124
Chemical/Pharm GKB GenePA164720918
Clinical trialINPP5J
Miscellaneous
canSAR (ICR)INPP5J (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineINPP5J
EVEXINPP5J
GoPubMedINPP5J
iHOPINPP5J
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:40:32 CET 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.