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IYD (iodotyrosine deiodinase)

Identity

Other namesC6orf71
DEHAL1
IYD-1
TDH4
HGNC (Hugo) IYD
LocusID (NCBI) 389434
Atlas_Id 47543
Location 6q25.1  [Link to chromosome band 6q25]
Location_base_pair Starts at 150690028 and ends at 150725765 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
IYD (6q25.1) / BIRC6 (2p22.3)NOLC1 (10q24.32) / IYD (6q25.1)IYD 6q25.1 / BIRC6 2p22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IYD   21071
Cards
Entrez_Gene (NCBI)IYD  389434  iodotyrosine deiodinase
AliasesC6orf71; DEHAL1; IYD-1; TDH4
GeneCards (Weizmann)IYD
Ensembl hg19 (Hinxton)ENSG00000009765 [Gene_View]  chr6:150690028-150725765 [Contig_View]  IYD [Vega]
Ensembl hg38 (Hinxton)ENSG00000009765 [Gene_View]  chr6:150690028-150725765 [Contig_View]  IYD [Vega]
ICGC DataPortalENSG00000009765
TCGA cBioPortalIYD
AceView (NCBI)IYD
Genatlas (Paris)IYD
WikiGenes389434
SOURCE (Princeton)IYD
Genomic and cartography
GoldenPath hg19 (UCSC)IYD  -     chr6:150690028-150725765 +  6q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)IYD  -     6q25.1   [Description]    (hg38-Dec_2013)
EnsemblIYD - 6q25.1 [CytoView hg19]  IYD - 6q25.1 [CytoView hg38]
Mapping of homologs : NCBIIYD [Mapview hg19]  IYD [Mapview hg38]
OMIM274800   612025   
Gene and transcription
Genbank (Entrez)AI823392 AK129950 AY259176 AY259177 AY424901
RefSeq transcript (Entrez)NM_001164694 NM_001164695 NM_001318495 NM_203395
RefSeq genomic (Entrez)NC_000006 NC_018917 NG_016007 NT_025741 NW_004929328
Consensus coding sequences : CCDS (NCBI)IYD
Cluster EST : UnigeneHs.310225 [ NCBI ]
CGAP (NCI)Hs.310225
Alternative Splicing GalleryENSG00000009765
Gene ExpressionIYD [ NCBI-GEO ]   IYD [ EBI - ARRAY_EXPRESS ]   IYD [ SEEK ]   IYD [ MEM ]
Gene Expression Viewer (FireBrowse)IYD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)389434
GTEX Portal (Tissue expression)IYD
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PHW0 (Uniprot)
NextProtQ6PHW0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PHW0
Splice isoforms : SwissVarQ6PHW0 (Swissvar)
PhosPhoSitePlusQ6PHW0
Domains : Interpro (EBI)Nitroreductase    Nitroreductase-like   
Domain families : Pfam (Sanger)Nitroreductase (PF00881)   
Domain families : Pfam (NCBI)pfam00881   
DMDM Disease mutations389434
Blocks (Seattle)IYD
PDB (SRS)4TTB    4TTC   
PDB (PDBSum)4TTB    4TTC   
PDB (IMB)4TTB    4TTC   
PDB (RSDB)4TTB    4TTC   
Structural Biology KnowledgeBase4TTB    4TTC   
SCOP (Structural Classification of Proteins)4TTB    4TTC   
CATH (Classification of proteins structures)4TTB    4TTC   
SuperfamilyQ6PHW0
Human Protein AtlasENSG00000009765
Peptide AtlasQ6PHW0
HPRD16668
IPIIPI00465267   IPI00736489   IPI00385533   IPI00738915   IPI00737829   IPI00657934   IPI00737444   IPI00940869   IPI01010554   IPI00737053   
Protein Interaction databases
DIP (DOE-UCLA)Q6PHW0
IntAct (EBI)Q6PHW0
FunCoupENSG00000009765
BioGRIDIYD
STRING (EMBL)IYD
ZODIACIYD
Ontologies - Pathways
QuickGOQ6PHW0
Ontology : AmiGOiodide peroxidase activity  protein binding  plasma membrane  thyroid hormone generation  integral component of membrane  oxidoreductase activity  oxidation-reduction process  cellular oxidant detoxification  
Ontology : EGO-EBIiodide peroxidase activity  protein binding  plasma membrane  thyroid hormone generation  integral component of membrane  oxidoreductase activity  oxidation-reduction process  cellular oxidant detoxification  
Pathways : KEGGThyroid hormone synthesis   
NDEx NetworkIYD
Atlas of Cancer Signalling NetworkIYD
Wikipedia pathwaysIYD
Orthology - Evolution
OrthoDB389434
GeneTree (enSembl)ENSG00000009765
Phylogenetic Trees/Animal Genes : TreeFamIYD
Homologs : HomoloGeneIYD
Homology/Alignments : Family Browser (UCSC)IYD
Gene fusions - Rearrangements
Fusion: TCGAIYD 6q25.1 BIRC6 2p22.3 THCA
Polymorphisms : SNP, variants
NCBI Variation ViewerIYD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IYD
dbVarIYD
ClinVarIYD
1000_GenomesIYD 
Exome Variant ServerIYD
ExAC (Exome Aggregation Consortium)IYD (select the gene name)
Genetic variants : HAPMAP389434
Genomic Variants (DGV)IYD [DGVbeta]
Mutations
ICGC Data PortalIYD 
TCGA Data PortalIYD 
Broad Tumor PortalIYD
OASIS PortalIYD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIYD 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IYD
DgiDB (Drug Gene Interaction Database)IYD
DoCM (Curated mutations)IYD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IYD (select a term)
intoGenIYD
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)6:150690028-150725765  ENSG00000009765
CONAN: Copy Number AnalysisIYD 
Mutations and Diseases : HGMDIYD
OMIM274800    612025   
MedgenIYD
Genetic Testing Registry IYD
NextProtQ6PHW0 [Medical]
TSGene389434
GENETestsIYD
Huge Navigator IYD [HugePedia]
snp3D : Map Gene to Disease389434
BioCentury BCIQIYD
ClinGenIYD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD389434
Chemical/Pharm GKB GenePA162392352
Clinical trialIYD
Miscellaneous
canSAR (ICR)IYD (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIYD
EVEXIYD
GoPubMedIYD
iHOPIYD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 18:55:42 CEST 2016

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