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IYD (iodotyrosine deiodinase)

Identity

Other namesC6orf71
DEHAL1
TDH4
dJ422F24.1
HGNC (Hugo) IYD
LocusID (NCBI) 389434
Location 6q25.1
Location_base_pair Starts at 150690028 and ends at 150725765 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IYD   21071
Cards
Entrez_Gene (NCBI)IYD  389434  iodotyrosine deiodinase
GeneCards (Weizmann)IYD
Ensembl (Hinxton)ENSG00000009765 [Gene_View]  chr6:150690028-150725765 [Contig_View]  IYD [Vega]
ICGC DataPortalENSG00000009765
cBioPortalIYD
AceView (NCBI)IYD
Genatlas (Paris)IYD
WikiGenes389434
SOURCE (Princeton)NM_001164694 NM_001164695 NM_203395
Genomic and cartography
GoldenPath (UCSC)IYD  -  6q25.1   chr6:150690028-150725765 +  6q25.1   [Description]    (hg19-Feb_2009)
EnsemblIYD - 6q25.1 [CytoView]
Mapping of homologs : NCBIIYD [Mapview]
OMIM274800   612025   
Gene and transcription
Genbank (Entrez)AI823392 AK129950 AY259176 AY259177 AY424901
RefSeq transcript (Entrez)NM_001164694 NM_001164695 NM_203395
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NG_016007 NT_025741 NW_001838990 NW_004929328
Consensus coding sequences : CCDS (NCBI)IYD
Cluster EST : UnigeneHs.310225 [ NCBI ]
CGAP (NCI)Hs.310225
Alternative Splicing : Fast-db (Paris)GSHG0026118
Alternative Splicing GalleryENSG00000009765
Gene ExpressionIYD [ NCBI-GEO ]     IYD [ SEEK ]   IYD [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PHW0 (Uniprot)
NextProtQ6PHW0  [Medical]
With graphics : InterProQ6PHW0
Splice isoforms : SwissVarQ6PHW0 (Swissvar)
Catalytic activity : Enzyme1.22.1.1 [ Enzyme-Expasy ]   1.22.1.11.22.1.1 [ IntEnz-EBI ]   1.22.1.1 [ BRENDA ]   1.22.1.1 [ KEGG ]   
Domains : Interpro (EBI)Nitroreductase-like [organisation]  
Related proteins : CluSTrQ6PHW0
Domain families : Pfam (Sanger)Nitroreductase (PF00881)   
Domain families : Pfam (NCBI)pfam00881   
DMDM Disease mutations389434
Blocks (Seattle)Q6PHW0
Human Protein AtlasENSG00000009765 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ6PHW0
HPRD16668
IPIIPI00465267   IPI00736489   IPI00385533   IPI00738915   IPI00737829   IPI00657934   IPI00737444   IPI00940869   IPI01010554   IPI00737053   
Protein Interaction databases
DIP (DOE-UCLA)Q6PHW0
IntAct (EBI)Q6PHW0
FunCoupENSG00000009765
BioGRIDIYD
InParanoidQ6PHW0
Interologous Interaction database Q6PHW0
IntegromeDBIYD
STRING (EMBL)IYD
Ontologies - Pathways
Ontology : AmiGOiodide peroxidase activity  plasma membrane  thyroid hormone generation  integral to membrane  oxidoreductase activity  cellular nitrogen compound metabolic process  small molecule metabolic process  
Ontology : EGO-EBIiodide peroxidase activity  plasma membrane  thyroid hormone generation  integral to membrane  oxidoreductase activity  cellular nitrogen compound metabolic process  small molecule metabolic process  
Pathways : KEGGThyroid hormone synthesis   
Protein Interaction DatabaseIYD
Wikipedia pathwaysIYD
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)IYD
snp3D : Map Gene to Disease389434
SNP (GeneSNP Utah)IYD
SNP : HGBaseIYD
Genetic variants : HAPMAPIYD
Exome VariantIYD
1000_GenomesIYD 
ICGC programENSG00000009765 
Somatic Mutations in Cancer : COSMICIYD 
CONAN: Copy Number AnalysisIYD 
Mutations and Diseases : HGMDIYD
Genomic VariantsIYD  IYD [DGVbeta]
dbVarIYD
ClinVarIYD
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM274800    612025   
MedgenIYD
GENETestsIYD
Disease Genetic AssociationIYD
Huge Navigator IYD [HugePedia]  IYD [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneIYD
Homology/Alignments : Family Browser (UCSC)IYD
Phylogenetic Trees/Animal Genes : TreeFamIYD
Chemical/Protein Interactions : CTD389434
Chemical/Pharm GKB GenePA162392352
Clinical trialIYD
Cancer Resource (Charite)ENSG00000009765
Other databases
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
CoreMineIYD
iHOPIYD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 17:01:24 CEST 2014

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