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IYD (iodotyrosine deiodinase)

Identity

Other namesC6orf71
DEHAL1
TDH4
dJ422F24.1
HGNC (Hugo) IYD
LocusID (NCBI) 389434
Atlas_Id 47543
Location 6q25.1
Location_base_pair Starts at 150690028 and ends at 150725765 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IYD   21071
Cards
Entrez_Gene (NCBI)IYD  389434  iodotyrosine deiodinase
GeneCards (Weizmann)IYD
Ensembl hg19 (Hinxton)ENSG00000009765 [Gene_View]  chr6:150690028-150725765 [Contig_View]  IYD [Vega]
Ensembl hg38 (Hinxton)ENSG00000009765 [Gene_View]  chr6:150690028-150725765 [Contig_View]  IYD [Vega]
ICGC DataPortalENSG00000009765
TCGA cBioPortalIYD
AceView (NCBI)IYD
Genatlas (Paris)IYD
WikiGenes389434
SOURCE (Princeton)IYD
Genomic and cartography
GoldenPath hg19 (UCSC)IYD  -     chr6:150690028-150725765 +  6q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)IYD  -     6q25.1   [Description]    (hg38-Dec_2013)
EnsemblIYD - 6q25.1 [CytoView hg19]  IYD - 6q25.1 [CytoView hg38]
Mapping of homologs : NCBIIYD [Mapview hg19]  IYD [Mapview hg38]
OMIM274800   612025   
Gene and transcription
Genbank (Entrez)AI823392 AK129950 AY259176 AY259177 AY424901
RefSeq transcript (Entrez)NM_001164694 NM_001164695 NM_203395
RefSeq genomic (Entrez)NC_000006 NC_018917 NG_016007 NT_025741 NW_004929328
Consensus coding sequences : CCDS (NCBI)IYD
Cluster EST : UnigeneHs.310225 [ NCBI ]
CGAP (NCI)Hs.310225
Alternative Splicing : Fast-db (Paris)GSHG0026118
Alternative Splicing GalleryENSG00000009765
Gene ExpressionIYD [ NCBI-GEO ]     IYD [ SEEK ]   IYD [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PHW0 (Uniprot)
NextProtQ6PHW0  [Medical]
With graphics : InterProQ6PHW0
Splice isoforms : SwissVarQ6PHW0 (Swissvar)
Catalytic activity : Enzyme1.22.1.1 [ Enzyme-Expasy ]   1.22.1.11.22.1.1 [ IntEnz-EBI ]   1.22.1.1 [ BRENDA ]   1.22.1.1 [ KEGG ]   
Domains : Interpro (EBI)Nitroreductase    Nitroreductase-like   
Related proteins : CluSTrQ6PHW0
Domain families : Pfam (Sanger)Nitroreductase (PF00881)   
Domain families : Pfam (NCBI)pfam00881   
DMDM Disease mutations389434
Blocks (Seattle)Q6PHW0
PDB (SRS)4TTB    4TTC   
PDB (PDBSum)4TTB    4TTC   
PDB (IMB)4TTB    4TTC   
PDB (RSDB)4TTB    4TTC   
Human Protein AtlasENSG00000009765
Peptide AtlasQ6PHW0
HPRD16668
IPIIPI00465267   IPI00736489   IPI00385533   IPI00738915   IPI00737829   IPI00657934   IPI00737444   IPI00940869   IPI01010554   IPI00737053   
Protein Interaction databases
DIP (DOE-UCLA)Q6PHW0
IntAct (EBI)Q6PHW0
FunCoupENSG00000009765
BioGRIDIYD
IntegromeDBIYD
STRING (EMBL)IYD
Ontologies - Pathways
QuickGOQ6PHW0
Ontology : AmiGOiodide peroxidase activity  protein binding  plasma membrane  thyroid hormone generation  integral component of membrane  oxidoreductase activity  cellular nitrogen compound metabolic process  small molecule metabolic process  oxidation-reduction process  
Ontology : EGO-EBIiodide peroxidase activity  protein binding  plasma membrane  thyroid hormone generation  integral component of membrane  oxidoreductase activity  cellular nitrogen compound metabolic process  small molecule metabolic process  oxidation-reduction process  
Pathways : KEGGThyroid hormone synthesis   
Protein Interaction DatabaseIYD
DoCM (Curated mutations)IYD
Wikipedia pathwaysIYD
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerIYD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IYD
dbVarIYD
ClinVarIYD
1000_GenomesIYD 
Exome Variant ServerIYD
SNP (GeneSNP Utah)IYD
SNP : HGBaseIYD
Genetic variants : HAPMAPIYD
Genomic Variants (DGV)IYD [DGVbeta]
Mutations
ICGC Data PortalIYD 
TCGA Data PortalIYD 
Tumor PortalIYD
Somatic Mutations in Cancer : COSMICIYD 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)6:150690028-150725765
CONAN: Copy Number AnalysisIYD 
Mutations and Diseases : HGMDIYD
OMIM274800    612025   
MedgenIYD
NextProtQ6PHW0 [Medical]
GENETestsIYD
Disease Genetic AssociationIYD
Huge Navigator IYD [HugePedia]  IYD [HugeCancerGEM]
snp3D : Map Gene to Disease389434
DGIdb (Drug Gene Interaction db)IYD
General knowledge
Homologs : HomoloGeneIYD
Homology/Alignments : Family Browser (UCSC)IYD
Phylogenetic Trees/Animal Genes : TreeFamIYD
Chemical/Protein Interactions : CTD389434
Chemical/Pharm GKB GenePA162392352
Clinical trialIYD
Cancer Resource (Charite)ENSG00000009765
Other databases
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
CoreMineIYD
GoPubMedIYD
iHOPIYD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Apr 13 14:37:42 CEST 2015

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