KAT2B (K(lysine) acetyltransferase 2B)

Identity

Other names	CAF
	P
	P/CAF
	PCAF
HGNC	KAT2B
Location	3p24
Location_base_pair	Starts at 20056528 and ends at 20170900 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	KAT2B   8638
Entrez_Gene	KAT2B  8850  K(lysine) acetyltransferase 2B
	Cards
GeneCards	KAT2B
Ensembl	KAT2B [Search_View]   ENSG00000114166 [Gene_View]
Genatlas	KAT2B
GeneLynx	KAT2B
eGenome	KAT2B
euGene	8850
	Genomic and cartography
GoldenPath	KAT2B  -  3p24   chr3:20056528-20170900 +  3p24.3   [Description]    (hg18-March_2006)
Ensembl	KAT2B - 3p24.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	KAT2B
	Gene and transcription
Genbank	AL832173 [ ENTREZ ]
Genbank	BC060823 [ ENTREZ ]
Genbank	BC070075 [ ENTREZ ]
Genbank	CR592587 [ ENTREZ ]
Genbank	U57317 [ ENTREZ ]
RefSeq	NM_003884 [ SRS ]    NM_003884 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	AC_000135 [ SRS ]    AC_000135 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022517 [ SRS ]    NT_022517 [ ENTREZ ]
RefSeq	NW_001838877 [ SRS ]    NW_001838877 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
AceView	KAT2B AceView - NCBI
Unigene	Hs.533055 [ SRS ]    Hs.533055 [ NCBI ]     HS533055 [ spliceNest ]
Fast-db	2970 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q92831 [ SRS]    Q92831 [ EXPASY ]     Q92831 [ INTERPRO ]     Q92831 [ UNIPROT ]
Prosite	PS00633 BROMODOMAIN_1 [ SRS ]    PS00633 BROMODOMAIN_1 [ Expasy ]
Prosite	PS50014 BROMODOMAIN_2 [ SRS ]    PS50014 BROMODOMAIN_2 [ Expasy ]
Prosite	PS51186 GNAT [ SRS ]    PS51186 GNAT [ Expasy ]
Interpro	IPR016181 Acyl_CoA_acyltransferase [ SRS ]    IPR016181 Acyl_CoA_acyltransferase [ EBI ]
Interpro	IPR001487 Bromodomain [ SRS ]    IPR001487 Bromodomain [ EBI ]
Interpro	IPR000182 GCN5-rel_AcTrfase [ SRS ]    IPR000182 GCN5-rel_AcTrfase [ EBI ]
Interpro	IPR016376 Hist_acetylase_PCAF [ SRS ]    IPR016376 Hist_acetylase_PCAF [ EBI ]
Interpro	IPR009464 PCAF_N [ SRS ]    IPR009464 PCAF_N [ EBI ]
CluSTr	Q92831
Pfam	PF00583 Acetyltransf_1 [ SRS ]    PF00583 Acetyltransf_1 [ Sanger ]    pfam00583 [ NCBI-CDD ]
Pfam	PF00439 Bromodomain [ SRS ]    PF00439 Bromodomain [ Sanger ]    pfam00439 [ NCBI-CDD ]
Pfam	PF06466 PCAF_N [ SRS ]    PF06466 PCAF_N [ Sanger ]    pfam06466 [ NCBI-CDD ]
Smart	SM00297 BROMO [EMBL]
Blocks	Q92831
PDB	1CM0 [ SRS ]    1CM0 [ PdbSum ],   1CM0 [ IMB ]   1CM0 [ RSDB ]
PDB	1JM4 [ SRS ]    1JM4 [ PdbSum ],   1JM4 [ IMB ]   1JM4 [ RSDB ]
PDB	1N72 [ SRS ]    1N72 [ PdbSum ],   1N72 [ IMB ]   1N72 [ RSDB ]
PDB	1WUG [ SRS ]    1WUG [ PdbSum ],   1WUG [ IMB ]   1WUG [ RSDB ]
PDB	1WUM [ SRS ]    1WUM [ PdbSum ],   1WUM [ IMB ]   1WUM [ RSDB ]
PDB	1ZS5 [ SRS ]    1ZS5 [ PdbSum ],   1ZS5 [ IMB ]   1ZS5 [ RSDB ]
PDB	2RNW [ SRS ]    2RNW [ PdbSum ],   2RNW [ IMB ]   2RNW [ RSDB ]
PDB	2RNX [ SRS ]    2RNX [ PdbSum ],   2RNX [ IMB ]   2RNX [ RSDB ]
HPRD	06780
	Protein Interaction databases
DIP	Q92831
IntAct	Q92831
	Polymorphism : SNP, mutations, diseases
OMIM	602303    [ map ]
GENECLINICS	602303
SNP	KAT2B [dbSNP-NCBI]
SNP	NM_003884 [SNP-NCI]
SNP	KAT2B [GeneSNPs - Utah]  KAT2B] [HGBASE - SRS]
HAPMAP	KAT2B [HAPMAP]
HGMD	KAT2B
	General knowledge
Family Browser	KAT2B [UCSC Family Browser]
SOURCE	NM_003884
SMD	Hs.533055
SAGE	Hs.533055
Enzyme	2.3.1.48 [ Enzyme-Expasy ]   2.3.1.48 [ Enzyme-SRS ]   2.3.1.48 [ IntEnz-EBI ]   2.3.1.48 [ BRENDA ]   2.3.1.48 [ KEGG ]   2.3.1.48 [ WIT ]
GO	histone acetyltransferase complex [Amigo]  histone acetyltransferase complex
GO	kinetochore [Amigo]  kinetochore
GO	transcription coactivator activity [Amigo]  transcription coactivator activity
GO	H3/H4 histone acetyltransferase activity [Amigo]  H3/H4 histone acetyltransferase activity
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	chromatin remodeling [Amigo]  chromatin remodeling
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	cell cycle [Amigo]  cell cycle
GO	cell cycle arrest [Amigo]  cell cycle arrest
GO	N-acetyltransferase activity [Amigo]  N-acetyltransferase activity
GO	metabolic process [Amigo]  metabolic process
GO	negative regulation of cell proliferation [Amigo]  negative regulation of cell proliferation
GO	histone acetylation [Amigo]  histone acetylation
GO	transferase activity [Amigo]  transferase activity
GO	N-terminal peptidyl-lysine acetylation [Amigo]  N-terminal peptidyl-lysine acetylation
GO	histone deacetylase binding [Amigo]  histone deacetylase binding
GO	interspecies interaction between organisms [Amigo]  interspecies interaction between organisms
GO	positive regulation of transcription [Amigo]  positive regulation of transcription
BIOCARTA	The information-processing pathway at the IFN-beta enhancer    [Genes]
BIOCARTA	Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells    [Genes]
BIOCARTA	Control of Gene Expression by Vitamin D Receptor    [Genes]
PubGene	KAT2B
TreeFam	KAT2B
CTD	8850 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	KAT2B Related clones (RZPD - Berlin)
	PubMed
PubMed	141 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:47:22 2008