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KAT8 (lysine acetyltransferase 8)

Identity

Alias_namesMYST1
MYST histone acetyltransferase 1
K(lysine) acetyltransferase 8
Alias_symbol (synonym)MOF
FLJ14040
hMOF
ZC2HC8
Other alias
HGNC (Hugo) KAT8
LocusID (NCBI) 84148
Atlas_Id 52336
Location 16p11.2  [Link to chromosome band 16p11]
Location_base_pair Starts at 31128985 and ends at 31142714 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KAT8 (16p11.2) / KAT8 (16p11.2)KAT8 (16p11.2) / SON (21q22.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KAT8   17933
Cards
Entrez_Gene (NCBI)KAT8  84148  lysine acetyltransferase 8
AliasesMOF; MYST1; ZC2HC8; hMOF
GeneCards (Weizmann)KAT8
Ensembl hg19 (Hinxton)ENSG00000103510 [Gene_View]  chr16:31128985-31142714 [Contig_View]  KAT8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000103510 [Gene_View]  chr16:31128985-31142714 [Contig_View]  KAT8 [Vega]
ICGC DataPortalENSG00000103510
TCGA cBioPortalKAT8
AceView (NCBI)KAT8
Genatlas (Paris)KAT8
WikiGenes84148
SOURCE (Princeton)KAT8
Genetics Home Reference (NIH)KAT8
Genomic and cartography
GoldenPath hg19 (UCSC)KAT8  -     chr16:31128985-31142714 +  16p11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KAT8  -     16p11.2   [Description]    (hg38-Dec_2013)
EnsemblKAT8 - 16p11.2 [CytoView hg19]  KAT8 - 16p11.2 [CytoView hg38]
Mapping of homologs : NCBIKAT8 [Mapview hg19]  KAT8 [Mapview hg38]
OMIM609912   
Gene and transcription
Genbank (Entrez)AA682878 AF217501 AF260665 AF289578 AK021872
RefSeq transcript (Entrez)NM_032188 NM_182958
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_187260 NW_004929400
Consensus coding sequences : CCDS (NCBI)KAT8
Cluster EST : UnigeneHs.533803 [ NCBI ]
CGAP (NCI)Hs.533803
Alternative Splicing GalleryENSG00000103510
Gene ExpressionKAT8 [ NCBI-GEO ]   KAT8 [ EBI - ARRAY_EXPRESS ]   KAT8 [ SEEK ]   KAT8 [ MEM ]
Gene Expression Viewer (FireBrowse)KAT8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84148
GTEX Portal (Tissue expression)KAT8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H7Z6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H7Z6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H7Z6
Splice isoforms : SwissVarQ9H7Z6
PhosPhoSitePlusQ9H7Z6
Domaine pattern : Prosite (Expaxy)MYST_HAT (PS51726)   
Domains : Interpro (EBI)Acyl_CoA_acyltransferase    Chromo/shadow_dom    Chromodomain-like    HAT_MYST-type    Tudor-knot   
Domain families : Pfam (Sanger)MOZ_SAS (PF01853)    Tudor-knot (PF11717)   
Domain families : Pfam (NCBI)pfam01853    pfam11717   
Domain families : Smart (EMBL)CHROMO (SM00298)  
Conserved Domain (NCBI)KAT8
DMDM Disease mutations84148
Blocks (Seattle)KAT8
PDB (SRS)2GIV    2PQ8    2Y0M    3QAH    3TOA    3TOB    4DNC   
PDB (PDBSum)2GIV    2PQ8    2Y0M    3QAH    3TOA    3TOB    4DNC   
PDB (IMB)2GIV    2PQ8    2Y0M    3QAH    3TOA    3TOB    4DNC   
PDB (RSDB)2GIV    2PQ8    2Y0M    3QAH    3TOA    3TOB    4DNC   
Structural Biology KnowledgeBase2GIV    2PQ8    2Y0M    3QAH    3TOA    3TOB    4DNC   
SCOP (Structural Classification of Proteins)2GIV    2PQ8    2Y0M    3QAH    3TOA    3TOB    4DNC   
CATH (Classification of proteins structures)2GIV    2PQ8    2Y0M    3QAH    3TOA    3TOB    4DNC   
SuperfamilyQ9H7Z6
Human Protein AtlasENSG00000103510
Peptide AtlasQ9H7Z6
HPRD11381
IPIIPI00550352   IPI00217660   
Protein Interaction databases
DIP (DOE-UCLA)Q9H7Z6
IntAct (EBI)Q9H7Z6
FunCoupENSG00000103510
BioGRIDKAT8
STRING (EMBL)KAT8
ZODIACKAT8
Ontologies - Pathways
QuickGOQ9H7Z6
Ontology : AmiGOhistone acetyltransferase complex  kinetochore  histone acetyltransferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  transcription factor binding  regulation of autophagy  acetyltransferase activity  histone acetylation  enzyme binding  myeloid cell differentiation  methylated histone binding  histone H4-K5 acetylation  histone H4-K8 acetylation  histone H4-K16 acetylation  histone H4-K16 acetylation  histone acetyltransferase activity (H4-K5 specific)  histone acetyltransferase activity (H4-K8 specific)  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  histone acetyltransferase activity (H4-K16 specific)  MLL1 complex  MSL complex  
Ontology : EGO-EBIhistone acetyltransferase complex  kinetochore  histone acetyltransferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  transcription factor binding  regulation of autophagy  acetyltransferase activity  histone acetylation  enzyme binding  myeloid cell differentiation  methylated histone binding  histone H4-K5 acetylation  histone H4-K8 acetylation  histone H4-K16 acetylation  histone H4-K16 acetylation  histone acetyltransferase activity (H4-K5 specific)  histone acetyltransferase activity (H4-K8 specific)  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  histone acetyltransferase activity (H4-K16 specific)  MLL1 complex  MSL complex  
NDEx NetworkKAT8
Atlas of Cancer Signalling NetworkKAT8
Wikipedia pathwaysKAT8
Orthology - Evolution
OrthoDB84148
GeneTree (enSembl)ENSG00000103510
Phylogenetic Trees/Animal Genes : TreeFamKAT8
HOVERGENQ9H7Z6
HOGENOMQ9H7Z6
Homologs : HomoloGeneKAT8
Homology/Alignments : Family Browser (UCSC)KAT8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKAT8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KAT8
dbVarKAT8
ClinVarKAT8
1000_GenomesKAT8 
Exome Variant ServerKAT8
ExAC (Exome Aggregation Consortium)KAT8 (select the gene name)
Genetic variants : HAPMAP84148
Genomic Variants (DGV)KAT8 [DGVbeta]
DECIPHER (Syndromes)16:31128985-31142714  ENSG00000103510
CONAN: Copy Number AnalysisKAT8 
Mutations
ICGC Data PortalKAT8 
TCGA Data PortalKAT8 
Broad Tumor PortalKAT8
OASIS PortalKAT8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKAT8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKAT8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KAT8
DgiDB (Drug Gene Interaction Database)KAT8
DoCM (Curated mutations)KAT8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KAT8 (select a term)
intoGenKAT8
Cancer3DKAT8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609912   
Orphanet
MedgenKAT8
Genetic Testing Registry KAT8
NextProtQ9H7Z6 [Medical]
TSGene84148
GENETestsKAT8
Huge Navigator KAT8 [HugePedia]
snp3D : Map Gene to Disease84148
BioCentury BCIQKAT8
ClinGenKAT8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84148
Chemical/Pharm GKB GenePA38476
Clinical trialKAT8
Miscellaneous
canSAR (ICR)KAT8 (select the gene name)
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKAT8
EVEXKAT8
GoPubMedKAT8
iHOPKAT8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:11:25 CET 2017

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