Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KATNB1 (katanin regulatory subunit B1)

Identity

Alias_nameskatanin p80 (WD40-containing) subunit B 1
katanin p80 (WD repeat containing) subunit B 1
Other aliasKAT
LIS6
HGNC (Hugo) KATNB1
LocusID (NCBI) 10300
Atlas_Id 64744
Location 16q21  [Link to chromosome band 16q21]
Location_base_pair Starts at 57735748 and ends at 57757250 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KATNB1   6217
Cards
Entrez_Gene (NCBI)KATNB1  10300  katanin regulatory subunit B1
AliasesKAT; LIS6
GeneCards (Weizmann)KATNB1
Ensembl hg19 (Hinxton)ENSG00000140854 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140854 [Gene_View]  chr16:57735748-57757250 [Contig_View]  KATNB1 [Vega]
ICGC DataPortalENSG00000140854
TCGA cBioPortalKATNB1
AceView (NCBI)KATNB1
Genatlas (Paris)KATNB1
WikiGenes10300
SOURCE (Princeton)KATNB1
Genetics Home Reference (NIH)KATNB1
Genomic and cartography
GoldenPath hg38 (UCSC)KATNB1  -     chr16:57735748-57757250 +  16q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KATNB1  -     16q21   [Description]    (hg19-Feb_2009)
EnsemblKATNB1 - 16q21 [CytoView hg19]  KATNB1 - 16q21 [CytoView hg38]
Mapping of homologs : NCBIKATNB1 [Mapview hg19]  KATNB1 [Mapview hg38]
OMIM602703   616212   
Gene and transcription
Genbank (Entrez)AB209250 AF052432 BC001353 BT007022 BU501165
RefSeq transcript (Entrez)NM_005886
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KATNB1
Cluster EST : UnigeneHs.732486 [ NCBI ]
CGAP (NCI)Hs.732486
Alternative Splicing GalleryENSG00000140854
Gene ExpressionKATNB1 [ NCBI-GEO ]   KATNB1 [ EBI - ARRAY_EXPRESS ]   KATNB1 [ SEEK ]   KATNB1 [ MEM ]
Gene Expression Viewer (FireBrowse)KATNB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10300
GTEX Portal (Tissue expression)KATNB1
Human Protein AtlasENSG00000140854-KATNB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BVA0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BVA0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BVA0
Splice isoforms : SwissVarQ9BVA0
PhosPhoSitePlusQ9BVA0
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    Katanin_bsu1    Katanin_C-terminal    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)Katanin_con80 (PF13925)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam13925    pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)KATNB1
DMDM Disease mutations10300
Blocks (Seattle)KATNB1
SuperfamilyQ9BVA0
Human Protein Atlas [tissue]ENSG00000140854-KATNB1 [tissue]
Peptide AtlasQ9BVA0
HPRD04081
IPIIPI00746256   IPI00556197   
Protein Interaction databases
DIP (DOE-UCLA)Q9BVA0
IntAct (EBI)Q9BVA0
FunCoupENSG00000140854
BioGRIDKATNB1
STRING (EMBL)KATNB1
ZODIACKATNB1
Ontologies - Pathways
QuickGOQ9BVA0
Ontology : AmiGOspindle pole  nucleus  cytoplasm  centrosome  cytosol  microtubule  plasma membrane  protein targeting  negative regulation of microtubule depolymerization  cell cycle  microtubule binding  katanin complex  katanin complex  microtubule-severing ATPase activity  positive regulation of cell death  positive regulation of neuron projection development  microtubule cytoskeleton  membrane  axon  growth cone  midbody  positive regulation of microtubule depolymerization  neuronal cell body  protein heterodimerization activity  microtubule severing  cell division  dynein complex binding  
Ontology : EGO-EBIspindle pole  nucleus  cytoplasm  centrosome  cytosol  microtubule  plasma membrane  protein targeting  negative regulation of microtubule depolymerization  cell cycle  microtubule binding  katanin complex  katanin complex  microtubule-severing ATPase activity  positive regulation of cell death  positive regulation of neuron projection development  microtubule cytoskeleton  membrane  axon  growth cone  midbody  positive regulation of microtubule depolymerization  neuronal cell body  protein heterodimerization activity  microtubule severing  cell division  dynein complex binding  
NDEx NetworkKATNB1
Atlas of Cancer Signalling NetworkKATNB1
Wikipedia pathwaysKATNB1
Orthology - Evolution
OrthoDB10300
GeneTree (enSembl)ENSG00000140854
Phylogenetic Trees/Animal Genes : TreeFamKATNB1
HOVERGENQ9BVA0
HOGENOMQ9BVA0
Homologs : HomoloGeneKATNB1
Homology/Alignments : Family Browser (UCSC)KATNB1
Gene fusions - Rearrangements
Fusion: Tumor Portal KATNB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKATNB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KATNB1
dbVarKATNB1
ClinVarKATNB1
1000_GenomesKATNB1 
Exome Variant ServerKATNB1
ExAC (Exome Aggregation Consortium)ENSG00000140854
GNOMAD BrowserENSG00000140854
Genetic variants : HAPMAP10300
Genomic Variants (DGV)KATNB1 [DGVbeta]
DECIPHERKATNB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKATNB1 
Mutations
ICGC Data PortalKATNB1 
TCGA Data PortalKATNB1 
Broad Tumor PortalKATNB1
OASIS PortalKATNB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKATNB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKATNB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KATNB1
DgiDB (Drug Gene Interaction Database)KATNB1
DoCM (Curated mutations)KATNB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KATNB1 (select a term)
intoGenKATNB1
Cancer3DKATNB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602703    616212   
Orphanet4059   
MedgenKATNB1
Genetic Testing Registry KATNB1
NextProtQ9BVA0 [Medical]
TSGene10300
GENETestsKATNB1
Target ValidationKATNB1
Huge Navigator KATNB1 [HugePedia]
snp3D : Map Gene to Disease10300
BioCentury BCIQKATNB1
ClinGenKATNB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10300
Chemical/Pharm GKB GenePA30018
Clinical trialKATNB1
Miscellaneous
canSAR (ICR)KATNB1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKATNB1
EVEXKATNB1
GoPubMedKATNB1
iHOPKATNB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:51:59 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.