KATNB1 (katanin regulatory subunit B1)

2019-04-01  

Identity

HGNC
LOCATION
16q21
LOCUSID
ALIAS
KAT,LIS6

Other Information

Locus ID:

NCBI: 10300
MIM: 602703
HGNC: 6217
Ensembl: ENSG00000140854

Variants:

dbSNP: 10300
ClinVar: 10300
TCGA: ENSG00000140854
COSMIC: KATNB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140854ENST00000379661Q9BVA0
ENSG00000140854ENST00000562592H3BPK1
ENSG00000140854ENST00000563462H3BTU7
ENSG00000140854ENST00000566726H3BPD8
ENSG00000140854ENST00000566785H3BTV8
ENSG00000140854ENST00000569627H3BT67

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
341377882021WDR62 localizes katanin at spindle poles to ensure synchronous chromosome segregation.7
342026292021Whole Exome Sequencing Is the Minimal Technological Approach in Probands Born to Consanguineous Couples.0
341377882021WDR62 localizes katanin at spindle poles to ensure synchronous chromosome segregation.7
342026292021Whole Exome Sequencing Is the Minimal Technological Approach in Probands Born to Consanguineous Couples.0
319444092020Katanin P80 correlates with larger tumor size, lymph node metastasis, and advanced TNM stage and predicts poor prognosis in non-small-cell lung cancer patients.7
332744992020Katanin P60 and P80 in papillary thyroid carcinoma patients: Indicators for exacerbated tumor features and worse disease-free survival.3
319444092020Katanin P80 correlates with larger tumor size, lymph node metastasis, and advanced TNM stage and predicts poor prognosis in non-small-cell lung cancer patients.7
332744992020Katanin P60 and P80 in papillary thyroid carcinoma patients: Indicators for exacerbated tumor features and worse disease-free survival.3
302233882018Katanin P80 expression correlates with lymph node metastasis and worse overall survival in patients with breast cancer.5
302233882018Katanin P80 expression correlates with lymph node metastasis and worse overall survival in patients with breast cancer.5
280791162017Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics.19
284369672017Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.86
280791162017Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics.19
284369672017Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.86
269292142016Proteomic Analysis of the Mammalian Katanin Family of Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1 (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing.29

Citation

Dessen P

KATNB1 (katanin regulatory subunit B1)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57839/katnb1