Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNQ3 (potassium voltage-gated channel, KQT-like subfamily, member 3)

Identity

Other namesBFNC2
EBN2
KV7.3
HGNC (Hugo) KCNQ3
LocusID (NCBI) 3786
Location 8q24.22
Location_base_pair Starts at 133133105 and ends at 133459509 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KCNQ3   6297
Cards
Entrez_Gene (NCBI)KCNQ3  3786  potassium voltage-gated channel, KQT-like subfamily, member 3
GeneCards (Weizmann)KCNQ3
Ensembl (Hinxton)ENSG00000184156 [Gene_View]  chr8:133133105-133459509 [Contig_View]  KCNQ3 [Vega]
ICGC DataPortalENSG00000184156
cBioPortalKCNQ3
AceView (NCBI)KCNQ3
Genatlas (Paris)KCNQ3
WikiGenes3786
SOURCE (Princeton)NM_001204824 NM_004519
Genomic and cartography
GoldenPath (UCSC)KCNQ3  -  8q24.22   chr8:133133105-133459509 -  8q24.22   [Description]    (hg19-Feb_2009)
EnsemblKCNQ3 - 8q24.22 [CytoView]
Mapping of homologs : NCBIKCNQ3 [Mapview]
OMIM121201   602232   
Gene and transcription
Genbank (Entrez)AB208890 AF033347 AK094705 AK095711 AK296293
RefSeq transcript (Entrez)NM_001204824 NM_004519
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NG_008854 NT_008046 NW_001839138 NW_004929340
Consensus coding sequences : CCDS (NCBI)KCNQ3
Cluster EST : UnigeneHs.374023 [ NCBI ]
CGAP (NCI)Hs.374023
Alternative Splicing : Fast-db (Paris)GSHG0029870
Alternative Splicing GalleryENSG00000184156
Gene ExpressionKCNQ3 [ NCBI-GEO ]     KCNQ3 [ SEEK ]   KCNQ3 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43525 (Uniprot)
NextProtO43525  [Medical]
With graphics : InterProO43525
Splice isoforms : SwissVarO43525 (Swissvar)
Domains : Interpro (EBI)Ankyrin-G_BS [organisation]   Ion_trans_dom [organisation]   K_chnl [organisation]   K_chnl_volt-dep_KCNQ [organisation]   K_chnl_volt-dep_KCNQ3 [organisation]   K_chnl_volt-dep_KCNQ_C [organisation]   VG_K_chnl [organisation]  
Related proteins : CluSTrO43525
Domain families : Pfam (Sanger)Ion_trans (PF00520)    KCNQ_channel (PF03520)    KCNQC3-Ank-G_bd (PF11956)   
Domain families : Pfam (NCBI)pfam00520    pfam03520    pfam11956   
DMDM Disease mutations3786
Blocks (Seattle)O43525
Human Protein AtlasENSG00000184156 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasO43525
HPRD09077
IPIIPI00012857   IPI00556205   IPI00976856   IPI00979950   
Protein Interaction databases
DIP (DOE-UCLA)O43525
IntAct (EBI)O43525
FunCoupENSG00000184156
BioGRIDKCNQ3
InParanoidO43525
Interologous Interaction database O43525
IntegromeDBKCNQ3
STRING (EMBL)KCNQ3
Ontologies - Pathways
Ontology : AmiGOvoltage-gated potassium channel activity  delayed rectifier potassium channel activity  potassium channel activity  plasma membrane  plasma membrane  potassium ion transport  synaptic transmission  axon guidance  voltage-gated potassium channel complex  node of Ranvier  regulation of ion transmembrane transport  axon initial segment  membrane hyperpolarization  potassium ion transmembrane transport  
Ontology : EGO-EBIvoltage-gated potassium channel activity  delayed rectifier potassium channel activity  potassium channel activity  plasma membrane  plasma membrane  potassium ion transport  synaptic transmission  axon guidance  voltage-gated potassium channel complex  node of Ranvier  regulation of ion transmembrane transport  axon initial segment  membrane hyperpolarization  potassium ion transmembrane transport  
Pathways : BIOCARTAIon Channels and Their Functional Role in Vascular Endothelium [Genes]   
Pathways : KEGGCholinergic synapse   
Protein Interaction DatabaseKCNQ3
Wikipedia pathwaysKCNQ3
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)KCNQ3
snp3D : Map Gene to Disease3786
SNP (GeneSNP Utah)KCNQ3
SNP : HGBaseKCNQ3
Genetic variants : HAPMAPKCNQ3
Exome VariantKCNQ3
1000_GenomesKCNQ3 
ICGC programENSG00000184156 
Somatic Mutations in Cancer : COSMICKCNQ3 
CONAN: Copy Number AnalysisKCNQ3 
Mutations and Diseases : HGMDKCNQ3
Genomic VariantsKCNQ3  KCNQ3 [DGVbeta]
dbVarKCNQ3
ClinVarKCNQ3
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM121201    602232   
MedgenKCNQ3
GENETestsKCNQ3
Disease Genetic AssociationKCNQ3
Huge Navigator KCNQ3 [HugePedia]  KCNQ3 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneKCNQ3
Homology/Alignments : Family Browser (UCSC)KCNQ3
Phylogenetic Trees/Animal Genes : TreeFamKCNQ3
Chemical/Protein Interactions : CTD3786
Chemical/Pharm GKB GenePA30075
Clinical trialKCNQ3
Cancer Resource (Charite)ENSG00000184156
Other databases
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
CoreMineKCNQ3
iHOPKCNQ3
OncoSearchKCNQ3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 14:00:49 CEST 2014

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