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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret jlhuret@AtlasGeneticsOncology.org
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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KCNQ3 (potassium channel, voltage gated KQT-like subfamily Q, member 3)

Identity

Other namesBFNC2
EBN2
KV7.3
HGNC (Hugo) KCNQ3
LocusID (NCBI) 3786
Location 8q24.22
Location_base_pair Starts at 133133105 and ends at 133459509 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KCNQ3   6297
Cards
Entrez_Gene (NCBI)KCNQ3  3786  potassium channel, voltage gated KQT-like subfamily Q, member 3
GeneCards (Weizmann)KCNQ3
Ensembl hg19 (Hinxton)ENSG00000184156 [Gene_View]  chr8:133133105-133459509 [Contig_View]  KCNQ3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000184156 [Gene_View]  chr8:133133105-133459509 [Contig_View]  KCNQ3 [Vega]
ICGC DataPortalENSG00000184156
cBioPortalKCNQ3
AceView (NCBI)KCNQ3
Genatlas (Paris)KCNQ3
WikiGenes3786
SOURCE (Princeton)KCNQ3
Genomic and cartography
GoldenPath hg19 (UCSC)KCNQ3  -     chr8:133133105-133459509 -  8q24.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KCNQ3  -     8q24.22   [Description]    (hg38-Dec_2013)
EnsemblKCNQ3 - 8q24.22 [CytoView hg19]  KCNQ3 - 8q24.22 [CytoView hg38]
Mapping of homologs : NCBIKCNQ3 [Mapview hg19]  KCNQ3 [Mapview hg38]
OMIM121201   602232   
Gene and transcription
Genbank (Entrez)AB208890 AF033347 AK094705 AK095711 AK296293
RefSeq transcript (Entrez)NM_001204824 NM_004519
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_008854 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)KCNQ3
Cluster EST : UnigeneHs.374023 [ NCBI ]
CGAP (NCI)Hs.374023
Alternative Splicing : Fast-db (Paris)GSHG0029870
Alternative Splicing GalleryENSG00000184156
Gene ExpressionKCNQ3 [ NCBI-GEO ]     KCNQ3 [ SEEK ]   KCNQ3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43525 (Uniprot)
NextProtO43525  [Medical]
With graphics : InterProO43525
Splice isoforms : SwissVarO43525 (Swissvar)
Domains : Interpro (EBI)Ankyrin-G_BS    Ion_trans_dom    K_chnl    K_chnl_volt-dep_KCNQ    K_chnl_volt-dep_KCNQ3    K_chnl_volt-dep_KCNQ_C    VG_K_chnl   
Related proteins : CluSTrO43525
Domain families : Pfam (Sanger)Ion_trans (PF00520)    KCNQ_channel (PF03520)    KCNQC3-Ank-G_bd (PF11956)   
Domain families : Pfam (NCBI)pfam00520    pfam03520    pfam11956   
DMDM Disease mutations3786
Blocks (Seattle)O43525
Human Protein AtlasENSG00000184156
Peptide AtlasO43525
HPRD09077
IPIIPI00012857   IPI00556205   IPI00976856   IPI00979950   
Protein Interaction databases
DIP (DOE-UCLA)O43525
IntAct (EBI)O43525
FunCoupENSG00000184156
BioGRIDKCNQ3
IntegromeDBKCNQ3
STRING (EMBL)KCNQ3
Ontologies - Pathways
QuickGOO43525
Ontology : AmiGOvoltage-gated potassium channel activity  delayed rectifier potassium channel activity  potassium channel activity  plasma membrane  plasma membrane  potassium ion transport  synaptic transmission  axon guidance  voltage-gated potassium channel complex  integral component of membrane  node of Ranvier  regulation of ion transmembrane transport  axon initial segment  membrane hyperpolarization  potassium ion transmembrane transport  
Ontology : EGO-EBIvoltage-gated potassium channel activity  delayed rectifier potassium channel activity  potassium channel activity  plasma membrane  plasma membrane  potassium ion transport  synaptic transmission  axon guidance  voltage-gated potassium channel complex  integral component of membrane  node of Ranvier  regulation of ion transmembrane transport  axon initial segment  membrane hyperpolarization  potassium ion transmembrane transport  
Pathways : BIOCARTAIon Channels and Their Functional Role in Vascular Endothelium [Genes]   
Pathways : KEGGCholinergic synapse   
Protein Interaction DatabaseKCNQ3
DoCM (Curated mutations)KCNQ3
Wikipedia pathwaysKCNQ3
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerKCNQ3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNQ3
dbVarKCNQ3
ClinVarKCNQ3
1000_GenomesKCNQ3 
Exome Variant ServerKCNQ3
SNP (GeneSNP Utah)KCNQ3
SNP : HGBaseKCNQ3
Genetic variants : HAPMAPKCNQ3
Genomic Variants (DGV)KCNQ3 [DGVbeta]
Mutations
ICGC Data PortalENSG00000184156 
Somatic Mutations in Cancer : COSMICKCNQ3 
CONAN: Copy Number AnalysisKCNQ3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)8:133133105-133459509
Mutations and Diseases : HGMDKCNQ3
OMIM121201    602232   
MedgenKCNQ3
NextProtO43525 [Medical]
GENETestsKCNQ3
Disease Genetic AssociationKCNQ3
Huge Navigator KCNQ3 [HugePedia]  KCNQ3 [HugeCancerGEM]
snp3D : Map Gene to Disease3786
DGIdb (Drug Gene Interaction db)KCNQ3
General knowledge
Homologs : HomoloGeneKCNQ3
Homology/Alignments : Family Browser (UCSC)KCNQ3
Phylogenetic Trees/Animal Genes : TreeFamKCNQ3
Chemical/Protein Interactions : CTD3786
Chemical/Pharm GKB GenePA30075
Clinical trialKCNQ3
Cancer Resource (Charite)ENSG00000184156
Other databases
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
CoreMineKCNQ3
GoPubMedKCNQ3
iHOPKCNQ3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 15:45:12 CET 2015

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