Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KIF11 (kinesin family member 11)

Identity

Alias_namesKNSL1
kinesin-like 1
Alias_symbol (synonym)Eg5
HKSP
TRIP5
Other aliasEG5
MCLMR
HGNC (Hugo) KIF11
LocusID (NCBI) 3832
Atlas_Id 43858
Location 10q23.33  [Link to chromosome band 10q23]
Location_base_pair Starts at 92593068 and ends at 92655395 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KIF11 (10q23.33) / KIF11 (10q23.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF11   6388
Cards
Entrez_Gene (NCBI)KIF11  3832  kinesin family member 11
AliasesEG5; HKSP; KNSL1; MCLMR; 
TRIP5
GeneCards (Weizmann)KIF11
Ensembl hg19 (Hinxton)ENSG00000138160 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138160 [Gene_View]  chr10:92593068-92655395 [Contig_View]  KIF11 [Vega]
ICGC DataPortalENSG00000138160
TCGA cBioPortalKIF11
AceView (NCBI)KIF11
Genatlas (Paris)KIF11
WikiGenes3832
SOURCE (Princeton)KIF11
Genetics Home Reference (NIH)KIF11
Genomic and cartography
GoldenPath hg38 (UCSC)KIF11  -     chr10:92593068-92655395 +  10q23.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIF11  -     10q23.33   [Description]    (hg19-Feb_2009)
EnsemblKIF11 - 10q23.33 [CytoView hg19]  KIF11 - 10q23.33 [CytoView hg38]
Mapping of homologs : NCBIKIF11 [Mapview hg19]  KIF11 [Mapview hg38]
OMIM148760   152950   
Gene and transcription
Genbank (Entrez)AA504625 AA857025 AB208964 AK314258 BC050421
RefSeq transcript (Entrez)NM_004523
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIF11
Cluster EST : UnigeneHs.8878 [ NCBI ]
CGAP (NCI)Hs.8878
Alternative Splicing GalleryENSG00000138160
Gene ExpressionKIF11 [ NCBI-GEO ]   KIF11 [ EBI - ARRAY_EXPRESS ]   KIF11 [ SEEK ]   KIF11 [ MEM ]
Gene Expression Viewer (FireBrowse)KIF11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3832
GTEX Portal (Tissue expression)KIF11
Protein : pattern, domain, 3D structure
UniProt/SwissProtP52732   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP52732  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP52732
Splice isoforms : SwissVarP52732
PhosPhoSitePlusP52732
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)Kinesin-assoc_MT-bd_dom    Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)    Microtub_bind (PF13931)   
Domain families : Pfam (NCBI)pfam00225    pfam13931   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF11
DMDM Disease mutations3832
Blocks (Seattle)KIF11
PDB (SRS)1II6    1Q0B    1X88    1YRS    2FKY    2FL2    2FL6    2FME    2G1Q    2GM1    2IEH    2PG2    2Q2Y    2Q2Z    2UYI    2UYM    2WOG    2X2R    2X7C    2X7D    2X7E    2XAE    3CJO    3HQD    3K3B    3K5E    3KEN    3L9H    3WPN    3ZCW    4A1Z    4A28    4A50    4A51    4A5Y    4AP0    4AQV    4AQW    4AS7    4B7B    4BBG    4BXN    4CK5    4CK6    4CK7    4ZCA    4ZHI    5JV3   
PDB (PDBSum)1II6    1Q0B    1X88    1YRS    2FKY    2FL2    2FL6    2FME    2G1Q    2GM1    2IEH    2PG2    2Q2Y    2Q2Z    2UYI    2UYM    2WOG    2X2R    2X7C    2X7D    2X7E    2XAE    3CJO    3HQD    3K3B    3K5E    3KEN    3L9H    3WPN    3ZCW    4A1Z    4A28    4A50    4A51    4A5Y    4AP0    4AQV    4AQW    4AS7    4B7B    4BBG    4BXN    4CK5    4CK6    4CK7    4ZCA    4ZHI    5JV3   
PDB (IMB)1II6    1Q0B    1X88    1YRS    2FKY    2FL2    2FL6    2FME    2G1Q    2GM1    2IEH    2PG2    2Q2Y    2Q2Z    2UYI    2UYM    2WOG    2X2R    2X7C    2X7D    2X7E    2XAE    3CJO    3HQD    3K3B    3K5E    3KEN    3L9H    3WPN    3ZCW    4A1Z    4A28    4A50    4A51    4A5Y    4AP0    4AQV    4AQW    4AS7    4B7B    4BBG    4BXN    4CK5    4CK6    4CK7    4ZCA    4ZHI    5JV3   
PDB (RSDB)1II6    1Q0B    1X88    1YRS    2FKY    2FL2    2FL6    2FME    2G1Q    2GM1    2IEH    2PG2    2Q2Y    2Q2Z    2UYI    2UYM    2WOG    2X2R    2X7C    2X7D    2X7E    2XAE    3CJO    3HQD    3K3B    3K5E    3KEN    3L9H    3WPN    3ZCW    4A1Z    4A28    4A50    4A51    4A5Y    4AP0    4AQV    4AQW    4AS7    4B7B    4BBG    4BXN    4CK5    4CK6    4CK7    4ZCA    4ZHI    5JV3   
Structural Biology KnowledgeBase1II6    1Q0B    1X88    1YRS    2FKY    2FL2    2FL6    2FME    2G1Q    2GM1    2IEH    2PG2    2Q2Y    2Q2Z    2UYI    2UYM    2WOG    2X2R    2X7C    2X7D    2X7E    2XAE    3CJO    3HQD    3K3B    3K5E    3KEN    3L9H    3WPN    3ZCW    4A1Z    4A28    4A50    4A51    4A5Y    4AP0    4AQV    4AQW    4AS7    4B7B    4BBG    4BXN    4CK5    4CK6    4CK7    4ZCA    4ZHI    5JV3   
SCOP (Structural Classification of Proteins)1II6    1Q0B    1X88    1YRS    2FKY    2FL2    2FL6    2FME    2G1Q    2GM1    2IEH    2PG2    2Q2Y    2Q2Z    2UYI    2UYM    2WOG    2X2R    2X7C    2X7D    2X7E    2XAE    3CJO    3HQD    3K3B    3K5E    3KEN    3L9H    3WPN    3ZCW    4A1Z    4A28    4A50    4A51    4A5Y    4AP0    4AQV    4AQW    4AS7    4B7B    4BBG    4BXN    4CK5    4CK6    4CK7    4ZCA    4ZHI    5JV3   
CATH (Classification of proteins structures)1II6    1Q0B    1X88    1YRS    2FKY    2FL2    2FL6    2FME    2G1Q    2GM1    2IEH    2PG2    2Q2Y    2Q2Z    2UYI    2UYM    2WOG    2X2R    2X7C    2X7D    2X7E    2XAE    3CJO    3HQD    3K3B    3K5E    3KEN    3L9H    3WPN    3ZCW    4A1Z    4A28    4A50    4A51    4A5Y    4AP0    4AQV    4AQW    4AS7    4B7B    4BBG    4BXN    4CK5    4CK6    4CK7    4ZCA    4ZHI    5JV3   
SuperfamilyP52732
Human Protein AtlasENSG00000138160
Peptide AtlasP52732
HPRD01023
IPIIPI00305289   
Protein Interaction databases
DIP (DOE-UCLA)P52732
IntAct (EBI)P52732
FunCoupENSG00000138160
BioGRIDKIF11
STRING (EMBL)KIF11
ZODIACKIF11
Ontologies - Pathways
QuickGOP52732
Ontology : AmiGOmitotic cell cycle  spindle pole  microtubule motor activity  ATP binding  spindle  cytosol  cytosol  kinesin complex  microtubule  spindle microtubule  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  spindle organization  mitotic spindle organization  chromosome segregation  mitotic centrosome separation  microtubule binding  ATP-dependent microtubule motor activity, plus-end-directed  membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  protein kinase binding  protein complex binding  regulation of mitotic centrosome separation  cell division  mitotic spindle assembly  mitotic spindle assembly  
Ontology : EGO-EBImitotic cell cycle  spindle pole  microtubule motor activity  ATP binding  spindle  cytosol  cytosol  kinesin complex  microtubule  spindle microtubule  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  spindle organization  mitotic spindle organization  chromosome segregation  mitotic centrosome separation  microtubule binding  ATP-dependent microtubule motor activity, plus-end-directed  membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  protein kinase binding  protein complex binding  regulation of mitotic centrosome separation  cell division  mitotic spindle assembly  mitotic spindle assembly  
NDEx NetworkKIF11
Atlas of Cancer Signalling NetworkKIF11
Wikipedia pathwaysKIF11
Orthology - Evolution
OrthoDB3832
GeneTree (enSembl)ENSG00000138160
Phylogenetic Trees/Animal Genes : TreeFamKIF11
HOVERGENP52732
HOGENOMP52732
Homologs : HomoloGeneKIF11
Homology/Alignments : Family Browser (UCSC)KIF11
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF11
dbVarKIF11
ClinVarKIF11
1000_GenomesKIF11 
Exome Variant ServerKIF11
ExAC (Exome Aggregation Consortium)KIF11 (select the gene name)
Genetic variants : HAPMAP3832
Genomic Variants (DGV)KIF11 [DGVbeta]
DECIPHERKIF11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIF11 
Mutations
ICGC Data PortalKIF11 
TCGA Data PortalKIF11 
Broad Tumor PortalKIF11
OASIS PortalKIF11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Vascular Anomaly and Lymphedema Mutation Database
BioMutasearch KIF11
DgiDB (Drug Gene Interaction Database)KIF11
DoCM (Curated mutations)KIF11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF11 (select a term)
intoGenKIF11
Cancer3DKIF11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM148760    152950   
Orphanet2336   
MedgenKIF11
Genetic Testing Registry KIF11
NextProtP52732 [Medical]
TSGene3832
GENETestsKIF11
Target ValidationKIF11
Huge Navigator KIF11 [HugePedia]
snp3D : Map Gene to Disease3832
BioCentury BCIQKIF11
ClinGenKIF11 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3832
Chemical/Pharm GKB GenePA30177
Clinical trialKIF11
Miscellaneous
canSAR (ICR)KIF11 (select the gene name)
Probes
Litterature
PubMed143 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF11
EVEXKIF11
GoPubMedKIF11
iHOPKIF11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:39:33 CEST 2017

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