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KIF23 (kinesin family member 23)

Identity

Alias_namesKNSL5
kinesin-like 5 (mitotic kinesin-like protein 1)
Alias_symbol (synonym)MKLP1
MKLP-1
Other aliasCHO1
HGNC (Hugo) KIF23
LocusID (NCBI) 9493
Atlas_Id 41068
Location 15q23  [Link to chromosome band 15q23]
Location_base_pair Starts at 69706585 and ends at 69740766 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RPLP1 (15q23) / KIF23 (15q23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF23   6392
Cards
Entrez_Gene (NCBI)KIF23  9493  kinesin family member 23
AliasesCHO1; KNSL5; MKLP-1; MKLP1
GeneCards (Weizmann)KIF23
Ensembl hg19 (Hinxton)ENSG00000137807 [Gene_View]  chr15:69706585-69740766 [Contig_View]  KIF23 [Vega]
Ensembl hg38 (Hinxton)ENSG00000137807 [Gene_View]  chr15:69706585-69740766 [Contig_View]  KIF23 [Vega]
ICGC DataPortalENSG00000137807
TCGA cBioPortalKIF23
AceView (NCBI)KIF23
Genatlas (Paris)KIF23
WikiGenes9493
SOURCE (Princeton)KIF23
Genetics Home Reference (NIH)KIF23
Genomic and cartography
GoldenPath hg19 (UCSC)KIF23  -     chr15:69706585-69740766 +  15q23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KIF23  -     15q23   [Description]    (hg38-Dec_2013)
EnsemblKIF23 - 15q23 [CytoView hg19]  KIF23 - 15q23 [CytoView hg38]
Mapping of homologs : NCBIKIF23 [Mapview hg19]  KIF23 [Mapview hg38]
OMIM605064   
Gene and transcription
Genbank (Entrez)AA291944 AI131325 AK303874 AK308322 AK308361
RefSeq transcript (Entrez)NM_001281301 NM_004856 NM_138555
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_042269 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)KIF23
Cluster EST : UnigeneHs.270845 [ NCBI ]
CGAP (NCI)Hs.270845
Alternative Splicing GalleryENSG00000137807
Gene ExpressionKIF23 [ NCBI-GEO ]   KIF23 [ EBI - ARRAY_EXPRESS ]   KIF23 [ SEEK ]   KIF23 [ MEM ]
Gene Expression Viewer (FireBrowse)KIF23 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9493
GTEX Portal (Tissue expression)KIF23
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02241   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02241  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02241
Splice isoforms : SwissVarQ02241
PhosPhoSitePlusQ02241
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)KIF23    Kif23_Arf-bd    Kinesin-like_fam    Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)    MKLP1_Arf_bdg (PF16540)   
Domain families : Pfam (NCBI)pfam00225    pfam16540   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF23
DMDM Disease mutations9493
Blocks (Seattle)KIF23
PDB (SRS)3VHX   
PDB (PDBSum)3VHX   
PDB (IMB)3VHX   
PDB (RSDB)3VHX   
Structural Biology KnowledgeBase3VHX   
SCOP (Structural Classification of Proteins)3VHX   
CATH (Classification of proteins structures)3VHX   
SuperfamilyQ02241
Human Protein AtlasENSG00000137807
Peptide AtlasQ02241
HPRD05455
IPIIPI00291579   IPI00293884   IPI01011119   IPI00873577   
Protein Interaction databases
DIP (DOE-UCLA)Q02241
IntAct (EBI)Q02241
FunCoupENSG00000137807
BioGRIDKIF23
STRING (EMBL)KIF23
ZODIACKIF23
Ontologies - Pathways
QuickGOQ02241
Ontology : AmiGOmitotic spindle elongation  mitotic cytokinesis  cytokinesis  actomyosin contractile ring assembly  microtubule motor activity  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  centrosome  spindle  cytosol  kinesin complex  microtubule  focal adhesion  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  microtubule binding  metabolic process  ATPase activity  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  positive regulation of cytokinesis  intercellular bridge  mitotic spindle midzone assembly  plus-end-directed vesicle transport along microtubule  mitotic spindle  centralspindlin complex  
Ontology : EGO-EBImitotic spindle elongation  mitotic cytokinesis  cytokinesis  actomyosin contractile ring assembly  microtubule motor activity  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  centrosome  spindle  cytosol  kinesin complex  microtubule  focal adhesion  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  microtubule binding  metabolic process  ATPase activity  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  positive regulation of cytokinesis  intercellular bridge  mitotic spindle midzone assembly  plus-end-directed vesicle transport along microtubule  mitotic spindle  centralspindlin complex  
Pathways : KEGGMicroRNAs in cancer   
NDEx NetworkKIF23
Atlas of Cancer Signalling NetworkKIF23
Wikipedia pathwaysKIF23
Orthology - Evolution
OrthoDB9493
GeneTree (enSembl)ENSG00000137807
Phylogenetic Trees/Animal Genes : TreeFamKIF23
HOVERGENQ02241
HOGENOMQ02241
Homologs : HomoloGeneKIF23
Homology/Alignments : Family Browser (UCSC)KIF23
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF23 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF23
dbVarKIF23
ClinVarKIF23
1000_GenomesKIF23 
Exome Variant ServerKIF23
ExAC (Exome Aggregation Consortium)KIF23 (select the gene name)
Genetic variants : HAPMAP9493
Genomic Variants (DGV)KIF23 [DGVbeta]
DECIPHER (Syndromes)15:69706585-69740766  ENSG00000137807
CONAN: Copy Number AnalysisKIF23 
Mutations
ICGC Data PortalKIF23 
TCGA Data PortalKIF23 
Broad Tumor PortalKIF23
OASIS PortalKIF23 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF23  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF23
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIF23
DgiDB (Drug Gene Interaction Database)KIF23
DoCM (Curated mutations)KIF23 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF23 (select a term)
intoGenKIF23
Cancer3DKIF23(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605064   
Orphanet13887   
MedgenKIF23
Genetic Testing Registry KIF23
NextProtQ02241 [Medical]
TSGene9493
GENETestsKIF23
Huge Navigator KIF23 [HugePedia]
snp3D : Map Gene to Disease9493
BioCentury BCIQKIF23
ClinGenKIF23
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9493
Chemical/Pharm GKB GenePA30181
Clinical trialKIF23
Miscellaneous
canSAR (ICR)KIF23 (select the gene name)
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF23
EVEXKIF23
GoPubMedKIF23
iHOPKIF23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:06:10 CEST 2017

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