KIF23 (kinesin family member 23)

2003-08-01  

Identity

HGNC
LOCATION
15q23
LOCUSID
ALIAS
CHO1,KNSL5,MKLP-1,MKLP1
FUSION GENES

Other Information

Locus ID:

NCBI: 9493
MIM: 605064
HGNC: 6392
Ensembl: ENSG00000137807

Variants:

dbSNP: 9493
ClinVar: 9493
TCGA: ENSG00000137807
COSMIC: KIF23

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137807ENST00000260363Q02241
ENSG00000137807ENST00000395392H7BYN4
ENSG00000137807ENST00000558346H0YME6
ENSG00000137807ENST00000559279A0A2U3TZL8
ENSG00000137807ENST00000561089H0YMJ4
ENSG00000137807ENST00000643966A0A2R8Y531
ENSG00000137807ENST00000647715Q02241

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231
KinesinsREACTOMER-HSA-983189
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic Telophase/CytokinesisREACTOMER-HSA-68884
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383362742024Identification and validation of KIF23 as a hypoxia-regulated lactate metabolism-related oncogene in uterine corpus endometrial carcinoma.1
383605982024SIRT7 promotes the proliferation and migration of anaplastic thyroid cancer cells by regulating the desuccinylation of KIF23.0
383362742024Identification and validation of KIF23 as a hypoxia-regulated lactate metabolism-related oncogene in uterine corpus endometrial carcinoma.1
383605982024SIRT7 promotes the proliferation and migration of anaplastic thyroid cancer cells by regulating the desuccinylation of KIF23.0
368940362023A Therapeutically Targetable TAZ-TEAD2 Pathway Drives the Growth of Hepatocellular Carcinoma via ANLN and KIF23.6
370106442023KIF23, under regulation by androgen receptor, contributes to nasopharyngeal carcinoma deterioration by activating the Wnt/β-catenin signaling pathway.0
371626182023Kinesin family member 23 knockdown inhibits cell proliferation and epithelial-mesenchymal transition in esophageal carcinoma by inactivating the Wnt/β-catenin pathway.2
371985022023KCNQ1OT1 promotes retinoblastoma progression by targeting miR-339-3p that suppresses KIF23.0
368940362023A Therapeutically Targetable TAZ-TEAD2 Pathway Drives the Growth of Hepatocellular Carcinoma via ANLN and KIF23.6
370106442023KIF23, under regulation by androgen receptor, contributes to nasopharyngeal carcinoma deterioration by activating the Wnt/β-catenin signaling pathway.0
371626182023Kinesin family member 23 knockdown inhibits cell proliferation and epithelial-mesenchymal transition in esophageal carcinoma by inactivating the Wnt/β-catenin pathway.2
371985022023KCNQ1OT1 promotes retinoblastoma progression by targeting miR-339-3p that suppresses KIF23.0
349833032022DEP domain containing 1B (DEPDC1B) exerts the tumor promoter in hepatocellular carcinoma through activating p53 signaling pathway via kinesin family member 23 (KIF23).2
354572542022Inhibition of KIF23 Alleviates IPAH by Targeting Pyroptosis and Proliferation of PASMCs.4
355243132022Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway.8

Citation

Dessen P

KIF23 (kinesin family member 23)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/41068/kif23