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KLF17 (Kruppel like factor 17)

Identity

Alias_namesZNF393
zinc finger protein 393
Alias_symbol (synonym)Zfp393
FLJ40160
Other alias
HGNC (Hugo) KLF17
LocusID (NCBI) 128209
Atlas_Id 51223
Location 1p34.1  [Link to chromosome band 1p34]
Location_base_pair Starts at 44118850 and ends at 44135137 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EWSR1 (22q12.2) / KLF17 (1p34.1)FUS (16p11.2) / KLF17 (1p34.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(1;16)(p34;p11) FUS/KLF17
t(1;16)(p34;p11) FUS/KLF17
t(1;22)(p34;q12) EWSR1/KLF17


External links

Nomenclature
HGNC (Hugo)KLF17   18830
Cards
Entrez_Gene (NCBI)KLF17  128209  Kruppel like factor 17
AliasesZNF393; Zfp393
GeneCards (Weizmann)KLF17
Ensembl hg19 (Hinxton)ENSG00000171872 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171872 [Gene_View]  ENSG00000171872 [Sequence]  chr1:44118850-44135137 [Contig_View]  KLF17 [Vega]
ICGC DataPortalENSG00000171872
TCGA cBioPortalKLF17
AceView (NCBI)KLF17
Genatlas (Paris)KLF17
WikiGenes128209
SOURCE (Princeton)KLF17
Genetics Home Reference (NIH)KLF17
Genomic and cartography
GoldenPath hg38 (UCSC)KLF17  -     chr1:44118850-44135137 +  1p34.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLF17  -     1p34.1   [Description]    (hg19-Feb_2009)
EnsemblKLF17 - 1p34.1 [CytoView hg19]  KLF17 - 1p34.1 [CytoView hg38]
Mapping of homologs : NCBIKLF17 [Mapview hg19]  KLF17 [Mapview hg38]
OMIM609602   
Gene and transcription
Genbank (Entrez)AK097479 AK308458 BC031250 BC035408 BC049844
RefSeq transcript (Entrez)NM_173484
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLF17
Cluster EST : UnigeneHs.647667 [ NCBI ]
CGAP (NCI)Hs.647667
Alternative Splicing GalleryENSG00000171872
Gene ExpressionKLF17 [ NCBI-GEO ]   KLF17 [ EBI - ARRAY_EXPRESS ]   KLF17 [ SEEK ]   KLF17 [ MEM ]
Gene Expression Viewer (FireBrowse)KLF17 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)128209
GTEX Portal (Tissue expression)KLF17
Human Protein AtlasENSG00000171872-KLF17 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JT82   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JT82  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JT82
Splice isoforms : SwissVarQ5JT82
PhosPhoSitePlusQ5JT82
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)KLF17
DMDM Disease mutations128209
Blocks (Seattle)KLF17
SuperfamilyQ5JT82
Human Protein Atlas [tissue]ENSG00000171872-KLF17 [tissue]
Peptide AtlasQ5JT82
HPRD08272
IPIIPI00328949   
Protein Interaction databases
DIP (DOE-UCLA)Q5JT82
IntAct (EBI)Q5JT82
FunCoupENSG00000171872
BioGRIDKLF17
STRING (EMBL)KLF17
ZODIACKLF17
Ontologies - Pathways
QuickGOQ5JT82
Ontology : AmiGODNA binding transcription factor activity  protein binding  nucleus  transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription regulatory region DNA binding  metal ion binding  
Ontology : EGO-EBIDNA binding transcription factor activity  protein binding  nucleus  transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription regulatory region DNA binding  metal ion binding  
NDEx NetworkKLF17
Atlas of Cancer Signalling NetworkKLF17
Wikipedia pathwaysKLF17
Orthology - Evolution
OrthoDB128209
GeneTree (enSembl)ENSG00000171872
Phylogenetic Trees/Animal Genes : TreeFamKLF17
HOVERGENQ5JT82
HOGENOMQ5JT82
Homologs : HomoloGeneKLF17
Homology/Alignments : Family Browser (UCSC)KLF17
Gene fusions - Rearrangements
Fusion : MitelmanEWSR1/KLF17 [22q12.2/1p34.1]  [t(1;22)(p34;q12)]  
Fusion : MitelmanFUS/KLF17 [16p11.2/1p34.1]  [t(1;16)(p34;p11)]  
Fusion : QuiverKLF17
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLF17 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLF17
dbVarKLF17
ClinVarKLF17
1000_GenomesKLF17 
Exome Variant ServerKLF17
ExAC (Exome Aggregation Consortium)ENSG00000171872
GNOMAD BrowserENSG00000171872
Genetic variants : HAPMAP128209
Genomic Variants (DGV)KLF17 [DGVbeta]
DECIPHERKLF17 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLF17 
Mutations
ICGC Data PortalKLF17 
TCGA Data PortalKLF17 
Broad Tumor PortalKLF17
OASIS PortalKLF17 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLF17  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLF17
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLF17
DgiDB (Drug Gene Interaction Database)KLF17
DoCM (Curated mutations)KLF17 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLF17 (select a term)
intoGenKLF17
Cancer3DKLF17(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609602   
Orphanet
DisGeNETKLF17
MedgenKLF17
Genetic Testing Registry KLF17
NextProtQ5JT82 [Medical]
TSGene128209
GENETestsKLF17
Target ValidationKLF17
Huge Navigator KLF17 [HugePedia]
snp3D : Map Gene to Disease128209
BioCentury BCIQKLF17
ClinGenKLF17
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD128209
Chemical/Pharm GKB GenePA134877071
Clinical trialKLF17
Miscellaneous
canSAR (ICR)KLF17 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLF17
EVEXKLF17
GoPubMedKLF17
iHOPKLF17
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:32:17 CEST 2018

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