KPNA2 (karyopherin alpha 2 (RAG cohort 1, importin alpha 1))

Identity

Other names	IPOA1
	QIP2
	RCH1
	SRP1alpha
Hugo	KPNA2
Location	17q24.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	KPNA2
GDB	KPNA2
Entrez_Gene	KPNA2  3838  karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
	Cards
GeneCards	KPNA2
Ensembl	KPNA2 [Search_View]   ENSG00000182481 [Gene_View]
Genatlas	KPNA2
GeneLynx	KPNA2
eGenome	KPNA2
euGene	3838
	Genomic and cartography
GoldenPath	KPNA2  -  17q24.2   chr17:63462310-63473431 +  17q24.2   [Description]    (hg18-March_2006)
Ensembl	KPNA2 - 17q24.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	KPNA2
	Gene and transcription
Genbank	AK024833 [ ENTREZ ]
Genbank	AK058111 [ ENTREZ ]
Genbank	AK291954 [ ENTREZ ]
Genbank	BC005978 [ ENTREZ ]
Genbank	BC013257 [ ENTREZ ]
RefSeq	NM_002266 [ SRS ]    NM_002266 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	AC_000149 [ SRS ]    AC_000149 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010783 [ SRS ]    NT_010783 [ ENTREZ ]
RefSeq	NW_001838454 [ SRS ]    NW_001838454 [ ENTREZ ]
RefSeq	NW_926918 [ SRS ]    NW_926918 [ ENTREZ ]
AceView	KPNA2 AceView - NCBI
Unigene	Hs.594238 [ SRS ]    Hs.594238 [ NCBI ]     HS594238 [ spliceNest ]
Fast-db	362 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P52292 [ SRS]    P52292 [ EXPASY ]     P52292 [ INTERPRO ]
Prosite	PS50176 ARM_REPEAT [ SRS ]    PS50176 ARM_REPEAT [ Expasy ]
Prosite	PS51214 IBB [ SRS ]    PS51214 IBB [ Expasy ]
Interpro	IPR011989 ARM-like [ SRS ]    IPR011989 ARM-like [ EBI ]
Interpro	IPR000225 Armadillo [ SRS ]    IPR000225 Armadillo [ EBI ]
Interpro	IPR002652 Importin-a-like_IBB-bd [ SRS ]    IPR002652 Importin-a-like_IBB-bd [ EBI ]
CluSTr	P52292
Pfam	PF00514 Arm [ SRS ]    PF00514 Arm [ Sanger ]    pfam00514 [ NCBI-CDD ]
Pfam	PF01749 IBB [ SRS ]    PF01749 IBB [ Sanger ]    pfam01749 [ NCBI-CDD ]
Smart	SM00185 ARM [EMBL]
Blocks	P52292
PDB	KPNA2 [ SRS ]    KPNA2 [ PdbSum ],   KPNA2 [ IMB ]   KPNA2 [ RSDB ]
HPRD	02818
	Protein Interaction databases
DIP	P52292
IntAct	P52292
	Polymorphism : SNP, mutations, diseases
OMIM	600685    [ map ]
GENECLINICS	600685
SNP	KPNA2 [dbSNP-NCBI]
SNP	NM_002266 [SNP-NCI]
SNP	KPNA2 [GeneSNPs - Utah]  KPNA2] [HGBASE - SRS]
HAPMAP	KPNA2 [HAPMAP]
COSMIC	KPNA2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	KPNA2
	General knowledge
Family Browser	KPNA2 [UCSC Family Browser]
SOURCE	NM_002266
SMD	Hs.594238
SAGE	Hs.594238
GO	regulation of DNA recombination [Amigo]  regulation of DNA recombination
GO	M phase specific microtubule process [Amigo]  M phase specific microtubule process
GO	G2 phase of mitotic cell cycle [Amigo]  G2 phase of mitotic cell cycle
GO	binding [Amigo]  binding
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	nucleus [Amigo]  nucleus
GO	nuclear pore [Amigo]  nuclear pore
GO	nucleoplasm [Amigo]  nucleoplasm
GO	cytoplasm [Amigo]  cytoplasm
GO	cytoplasm [Amigo]  cytoplasm
GO	DNA metabolic process [Amigo]  DNA metabolic process
GO	protein import into nucleus [Amigo]  protein import into nucleus
GO	NLS-bearing substrate import into nucleus [Amigo]  NLS-bearing substrate import into nucleus
GO	intracellular protein transport [Amigo]  intracellular protein transport
GO	nuclear localization sequence binding [Amigo]  nuclear localization sequence binding
GO	protein transporter activity [Amigo]  protein transporter activity
GO	interspecies interaction between organisms [Amigo]  interspecies interaction between organisms
BIOCARTA	Mechanism of Protein Import into the Nucleus    [Genes]
BIOCARTA	Role of Ran in mitotic spindle regulation    [Genes]
PubGene	KPNA2
TreeFam	KPNA2
CTD	3838 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	KPNA2 Related clones (RZPD - Berlin)
	PubMed
PubMed	121 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Jul 14 17:13:49 2008