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KYAT1 (kynurenine aminotransferase 1)

Identity

Other aliasCCBL1
GTK
KAT1
KATI
HGNC (Hugo) KYAT1
LocusID (NCBI) 883
Atlas_Id 78742
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 131595392 and ends at 131644354 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)KYAT1   1564
Cards
Entrez_Gene (NCBI)KYAT1  883  kynurenine aminotransferase 1
AliasesCCBL1; GTK; KAT1; KATI
GeneCards (Weizmann)KYAT1
Ensembl hg19 (Hinxton) [Gene_View]  chr9:131595392-131644354 [Contig_View]  KYAT1 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr9:131595392-131644354 [Contig_View]  KYAT1 [Vega]
TCGA cBioPortalKYAT1
AceView (NCBI)KYAT1
Genatlas (Paris)KYAT1
WikiGenes883
SOURCE (Princeton)KYAT1
Genetics Home Reference (NIH)KYAT1
Genomic and cartography
GoldenPath hg19 (UCSC)KYAT1  -     chr9:131595392-131644354 -  9q34.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KYAT1  -     9q34.11   [Description]    (hg38-Dec_2013)
EnsemblKYAT1 - 9q34.11 [CytoView hg19]  KYAT1 - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBIKYAT1 [Mapview hg19]  KYAT1 [Mapview hg38]
OMIM600547   
Gene and transcription
Genbank (Entrez)AK094505 AK291178 AK297995 AK314427 AU123740
RefSeq transcript (Entrez)NM_001122671 NM_001122672 NM_001287390 NM_004059
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KYAT1
Cluster EST : UnigeneHs.495250 [ NCBI ]
CGAP (NCI)Hs.495250
Gene ExpressionKYAT1 [ NCBI-GEO ]   KYAT1 [ EBI - ARRAY_EXPRESS ]   KYAT1 [ SEEK ]   KYAT1 [ MEM ]
Gene Expression Viewer (FireBrowse)KYAT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)883
GTEX Portal (Tissue expression)KYAT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16773   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16773  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16773
Splice isoforms : SwissVarQ16773
Catalytic activity : Enzyme2.6.1.7 [ Enzyme-Expasy ]   2.6.1.72.6.1.7 [ IntEnz-EBI ]   2.6.1.7 [ BRENDA ]   2.6.1.7 [ KEGG ]   
PhosPhoSitePlusQ16773
Domains : Interpro (EBI)Aminotransferase_I/II    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_major_sub1    PyrdxlP-dep_Trfase_major_sub2   
Domain families : Pfam (Sanger)Aminotran_1_2 (PF00155)   
Domain families : Pfam (NCBI)pfam00155   
Conserved Domain (NCBI)KYAT1
DMDM Disease mutations883
Blocks (Seattle)KYAT1
PDB (SRS)1W7L    1W7M    1W7N    3FVS    3FVU    3FVX    4WLH    4WLJ    4WP0   
PDB (PDBSum)1W7L    1W7M    1W7N    3FVS    3FVU    3FVX    4WLH    4WLJ    4WP0   
PDB (IMB)1W7L    1W7M    1W7N    3FVS    3FVU    3FVX    4WLH    4WLJ    4WP0   
PDB (RSDB)1W7L    1W7M    1W7N    3FVS    3FVU    3FVX    4WLH    4WLJ    4WP0   
Structural Biology KnowledgeBase1W7L    1W7M    1W7N    3FVS    3FVU    3FVX    4WLH    4WLJ    4WP0   
SCOP (Structural Classification of Proteins)1W7L    1W7M    1W7N    3FVS    3FVU    3FVX    4WLH    4WLJ    4WP0   
CATH (Classification of proteins structures)1W7L    1W7M    1W7N    3FVS    3FVU    3FVX    4WLH    4WLJ    4WP0   
SuperfamilyQ16773
Peptide AtlasQ16773
HPRD02769
IPIIPI01014100   IPI00181795   IPI00410254   IPI00002523   IPI00640577   IPI00513967   
Protein Interaction databases
DIP (DOE-UCLA)Q16773
IntAct (EBI)Q16773
BioGRIDKYAT1
STRING (EMBL)KYAT1
ZODIACKYAT1
Ontologies - Pathways
QuickGOQ16773
Ontology : AmiGOprotein binding  nucleoplasm  cytoplasm  cytosol  L-phenylalanine catabolic process  tryptophan catabolic process  cellular modified amino acid metabolic process  transaminase activity  cellular amino acid biosynthetic process  kynurenine-oxoglutarate transaminase activity  kynurenine-oxoglutarate transaminase activity  pyridoxal phosphate binding  protein homodimerization activity  L-phenylalanine:pyruvate aminotransferase activity  glutamine-phenylpyruvate transaminase activity  cysteine-S-conjugate beta-lyase activity  L-glutamine:pyruvate aminotransferase activity  kynurenine metabolic process  L-kynurenine catabolic process  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytoplasm  cytosol  L-phenylalanine catabolic process  tryptophan catabolic process  cellular modified amino acid metabolic process  transaminase activity  cellular amino acid biosynthetic process  kynurenine-oxoglutarate transaminase activity  kynurenine-oxoglutarate transaminase activity  pyridoxal phosphate binding  protein homodimerization activity  L-phenylalanine:pyruvate aminotransferase activity  glutamine-phenylpyruvate transaminase activity  cysteine-S-conjugate beta-lyase activity  L-glutamine:pyruvate aminotransferase activity  kynurenine metabolic process  L-kynurenine catabolic process  
NDEx NetworkKYAT1
Atlas of Cancer Signalling NetworkKYAT1
Wikipedia pathwaysKYAT1
Orthology - Evolution
OrthoDB883
Phylogenetic Trees/Animal Genes : TreeFamKYAT1
HOVERGENQ16773
HOGENOMQ16773
Homologs : HomoloGeneKYAT1
Homology/Alignments : Family Browser (UCSC)KYAT1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKYAT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KYAT1
dbVarKYAT1
ClinVarKYAT1
1000_GenomesKYAT1 
Exome Variant ServerKYAT1
ExAC (Exome Aggregation Consortium)KYAT1 (select the gene name)
Genetic variants : HAPMAP883
Genomic Variants (DGV)KYAT1 [DGVbeta]
DECIPHER (Syndromes)9:131595392-131644354  
CONAN: Copy Number AnalysisKYAT1 
Mutations
ICGC Data PortalKYAT1 
TCGA Data PortalKYAT1 
Broad Tumor PortalKYAT1
OASIS PortalKYAT1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDKYAT1
BioMutasearch KYAT1
DgiDB (Drug Gene Interaction Database)KYAT1
DoCM (Curated mutations)KYAT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KYAT1 (select a term)
intoGenKYAT1
Cancer3DKYAT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600547   
Orphanet
MedgenKYAT1
Genetic Testing Registry KYAT1
NextProtQ16773 [Medical]
TSGene883
GENETestsKYAT1
Huge Navigator KYAT1 [HugePedia]
snp3D : Map Gene to Disease883
BioCentury BCIQKYAT1
ClinGenKYAT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD883
Chemical/Pharm GKB GenePA26138
Clinical trialKYAT1
Miscellaneous
canSAR (ICR)KYAT1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKYAT1
EVEXKYAT1
GoPubMedKYAT1
iHOPKYAT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:10:41 CET 2017

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