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LACRT (lacritin)

Identity

Alias_symbol (synonym)LACRITIN
Other alias-
HGNC (Hugo) LACRT
LocusID (NCBI) 90070
Atlas_Id 43987
Location 12q13.2  [Link to chromosome band 12q13]
Location_base_pair Starts at 55024623 and ends at 55028663 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LACRT (12q13.2) / PINK1 (1p36.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LACRT   16430
Cards
Entrez_Gene (NCBI)LACRT  90070  lacritin
Aliases
GeneCards (Weizmann)LACRT
Ensembl hg19 (Hinxton)ENSG00000135413 [Gene_View]  chr12:55024623-55028663 [Contig_View]  LACRT [Vega]
Ensembl hg38 (Hinxton)ENSG00000135413 [Gene_View]  chr12:55024623-55028663 [Contig_View]  LACRT [Vega]
ICGC DataPortalENSG00000135413
TCGA cBioPortalLACRT
AceView (NCBI)LACRT
Genatlas (Paris)LACRT
WikiGenes90070
SOURCE (Princeton)LACRT
Genetics Home Reference (NIH)LACRT
Genomic and cartography
GoldenPath hg19 (UCSC)LACRT  -     chr12:55024623-55028663 -  12q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LACRT  -     12q13.2   [Description]    (hg38-Dec_2013)
EnsemblLACRT - 12q13.2 [CytoView hg19]  LACRT - 12q13.2 [CytoView hg38]
Mapping of homologs : NCBILACRT [Mapview hg19]  LACRT [Mapview hg38]
OMIM607360   
Gene and transcription
Genbank (Entrez)AF238867 BC062217 BC069317 HQ448432
RefSeq transcript (Entrez)NM_033277
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)LACRT
Cluster EST : UnigeneHs.307096 [ NCBI ]
CGAP (NCI)Hs.307096
Alternative Splicing GalleryENSG00000135413
Gene ExpressionLACRT [ NCBI-GEO ]   LACRT [ EBI - ARRAY_EXPRESS ]   LACRT [ SEEK ]   LACRT [ MEM ]
Gene Expression Viewer (FireBrowse)LACRT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90070
GTEX Portal (Tissue expression)LACRT
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZZ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZZ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZZ8
Splice isoforms : SwissVarQ9GZZ8
PhosPhoSitePlusQ9GZZ8
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)LACRT
DMDM Disease mutations90070
Blocks (Seattle)LACRT
SuperfamilyQ9GZZ8
Human Protein AtlasENSG00000135413
Peptide AtlasQ9GZZ8
HPRD06302
IPIIPI00020487   IPI01020758   IPI01021551   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZZ8
IntAct (EBI)Q9GZZ8
FunCoupENSG00000135413
BioGRIDLACRT
STRING (EMBL)LACRT
ZODIACLACRT
Ontologies - Pathways
QuickGOQ9GZZ8
Ontology : AmiGOglycoprotein binding  fibronectin binding  collagen binding  extracellular region  extracellular space  growth factor activity  positive regulation of cell proliferation  calcium-mediated signaling  secretory granule  calcineurin-NFAT signaling cascade  protein localization to Golgi apparatus  laminin-1 binding  protein N-terminus binding  positive regulation of epithelial cell proliferation  positive regulation of peptidyl-tyrosine phosphorylation  positive regulation of secretion  positive regulation of release of sequestered calcium ion into cytosol  positive regulation of NFAT protein import into nucleus  tear secretion  
Ontology : EGO-EBIglycoprotein binding  fibronectin binding  collagen binding  extracellular region  extracellular space  growth factor activity  positive regulation of cell proliferation  calcium-mediated signaling  secretory granule  calcineurin-NFAT signaling cascade  protein localization to Golgi apparatus  laminin-1 binding  protein N-terminus binding  positive regulation of epithelial cell proliferation  positive regulation of peptidyl-tyrosine phosphorylation  positive regulation of secretion  positive regulation of release of sequestered calcium ion into cytosol  positive regulation of NFAT protein import into nucleus  tear secretion  
NDEx NetworkLACRT
Atlas of Cancer Signalling NetworkLACRT
Wikipedia pathwaysLACRT
Orthology - Evolution
OrthoDB90070
GeneTree (enSembl)ENSG00000135413
Phylogenetic Trees/Animal Genes : TreeFamLACRT
HOVERGENQ9GZZ8
HOGENOMQ9GZZ8
Homologs : HomoloGeneLACRT
Homology/Alignments : Family Browser (UCSC)LACRT
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLACRT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LACRT
dbVarLACRT
ClinVarLACRT
1000_GenomesLACRT 
Exome Variant ServerLACRT
ExAC (Exome Aggregation Consortium)LACRT (select the gene name)
Genetic variants : HAPMAP90070
Genomic Variants (DGV)LACRT [DGVbeta]
DECIPHER (Syndromes)12:55024623-55028663  ENSG00000135413
CONAN: Copy Number AnalysisLACRT 
Mutations
ICGC Data PortalLACRT 
TCGA Data PortalLACRT 
Broad Tumor PortalLACRT
OASIS PortalLACRT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLACRT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLACRT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LACRT
DgiDB (Drug Gene Interaction Database)LACRT
DoCM (Curated mutations)LACRT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LACRT (select a term)
intoGenLACRT
Cancer3DLACRT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607360   
Orphanet
MedgenLACRT
Genetic Testing Registry LACRT
NextProtQ9GZZ8 [Medical]
TSGene90070
GENETestsLACRT
Huge Navigator LACRT [HugePedia]
snp3D : Map Gene to Disease90070
BioCentury BCIQLACRT
ClinGenLACRT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90070
Chemical/Pharm GKB GenePA30261
Clinical trialLACRT
Miscellaneous
canSAR (ICR)LACRT (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLACRT
EVEXLACRT
GoPubMedLACRT
iHOPLACRT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 13:12:23 CET 2017

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