Atlas of Genetics and Cytogenetics in Oncology and Haematology

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LGR4 (leucine-rich repeat containing G protein-coupled receptor 4)

Identity

Other namesGPR48
HGNC (Hugo) LGR4
LocusID (NCBI) 55366
Location 11p14.1
Location_base_pair Starts at 27387508 and ends at 27494334 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LGR4   13299
Entrez_Gene (NCBI)LGR4  55366  leucine-rich repeat containing G protein-coupled receptor 4
Cards
GeneCards (Weizmann)LGR4
Ensembl (Hinxton)ENSG00000205213 [Gene_View]  chr11:27387508-27494334 [Contig_View]  LGR4 [Vega]
AceView (NCBI)LGR4
Genatlas (Paris)LGR4
SOURCE (Stanford)NM_018490
Genomic and cartography
GoldenPath (UCSC)LGR4  -  11p14.1   chr11:27387508-27494334 -  11p14.1   [Description]    (hg19-Feb_2009)
EnsemblLGR4 - 11p14.1 [CytoView]
Mapping of homologs : NCBILGR4 [Mapview]
OMIM181500   606666   
Gene and transcription
Genbank (Entrez)AB209743 AF257182 AI699025 BC033039 CB047435
RefSeq transcript (SRS)NM_018490
RefSeq transcript (Entrez)NM_018490
RefSeq genomic (SRS)AC_000143 NC_000011 NC_018922 NT_009237 NW_001838022 NW_004078070
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NT_009237 NW_001838022 NW_004078070
Consensus coding sequences : CCDS (NCBI)LGR4
Cluster EST : UnigeneHs.502176 [ SRS ] Hs.502176 [ NCBI ]
CGAP (NCI)Hs.502176
Alternative Splicing : Fast-db (Paris)GSHG0005658
Alternative Splicing GalleryENSG00000205213
Gene ExpressionLGR4 [ NCBI-GEO ]   LGR4 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXB1 (SRS) Q9BXB1 (Uniprot)
NextProtQ9BXB1
With graphics : InterProQ9BXB1
Splice isoforms : SwissVarQ9BXB1(Swissvar)
Domaine pattern : Prosite (SRS)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)    LRR (PS51450)   
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)    LRR (PS51450)   
Domains : Interpro (SRS)7TM_GPCR_Rhodpsn    GPCR_Rhodpsn_supfam    Gphrmn_rcpt    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR-contain_N   
Domains : Interpro (EBI)7TM_GPCR_Rhodpsn    GPCR_Rhodpsn_supfam    Gphrmn_rcpt    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR-contain_N   
Related proteins : CluSTrQ9BXB1
Domain families : Pfam (SRS)7tm_1 (PF00001)    LRR_1 (PF00560)    LRRNT (PF01462)   
Domain families : Pfam (Sanger)7tm_1 (PF00001)    LRR_1 (PF00560)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam00001    pfam00560    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
DMDM55366
Blocks (Seattle)Q9BXB1
Human Protein AtlasENSG00000205213
HPRD05978
IPIIPI00217954   IPI00798136   IPI00982640   
Protein Interaction databases
DIP (DOE-UCLA)Q9BXB1
IntAct (EBI)Q9BXB1
FunCoupENSG00000205213
REACTOMELGR4
Protein Interaction Database55366
BioGRIDLGR4
InParanoidQ9BXB1
Interologous Interaction database Q9BXB1
IntegromeDBLGR4
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LGR4
SNP (GeneSNP Utah)LGR4
SNP : HGBaseLGR4
Genetic variants : HAPMAPLGR4
Somatic Mutations in Cancer : COSMICLGR4 
CONAN: Copy Number AnalysisLGR4 
Mutations and Diseases : HGMDLGR4
OMIM181500    606666   
GENETests181500    606666   
Disease Genetic AssociationLGR4
Huge Navigator LGR4 [HugePedia]  LGR4 [HugeCancerGEM]
Genomic VariantsLGR4  LGR4 [DGVbeta]
snp3D : Map Gene to Disease55366
General knowledge
Homologs : HomoloGeneLGR4
Homology/Alignments : Family Browser (UCSC)LGR4
Phylogenetic Trees/Animal Genes : TreeFamLGR4
Chemical/Protein Interactions : CTD55366
Chemical/Pharm GKB GenePA28893
Clinical trialLGR4
Cancer Resource (Charite)ENSG00000205213
Ontology : AmiGOG-protein coupled receptor activity  plasma membrane  integral to membrane  protein-hormone receptor activity  male genitalia development  negative regulation of transcription, DNA-dependent  positive regulation of transcription, DNA-dependent  epithelial cell proliferation  canonical Wnt receptor signaling pathway involved in metanephric kidney development  cell differentiation involved in metanephros development  metanephric glomerulus development  metanephric nephron tubule morphogenesis  positive regulation of branching involved in ureteric bud morphogenesis  
Ontology : EGO-EBIG-protein coupled receptor activity  plasma membrane  integral to membrane  protein-hormone receptor activity  male genitalia development  negative regulation of transcription, DNA-dependent  positive regulation of transcription, DNA-dependent  epithelial cell proliferation  canonical Wnt receptor signaling pathway involved in metanephric kidney development  cell differentiation involved in metanephros development  metanephric glomerulus development  metanephric nephron tubule morphogenesis  positive regulation of branching involved in ureteric bud morphogenesis  
Other databases
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
PubGeneLGR4
iHOPLGR4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:36:12 CEST 2013
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