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LILRB3 (leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3)

Identity

Alias_namesleukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
Alias_symbol (synonym)LIR-3
HL9
ILT5
LIR3
CD85a
PIRB
PIR-B
Other aliasCD85A
ILT-5
LILRA6
HGNC (Hugo) LILRB3
LocusID (NCBI) 11025
Atlas_Id 65265
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 54720147 and ends at 54746711 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
WDR74 (11q12.3) / LILRB3 (19q13.42)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LILRB3   6607
Cards
Entrez_Gene (NCBI)LILRB3  11025  leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
AliasesCD85A; HL9; ILT-5; ILT5; 
LILRA6; LIR-3; LIR3; PIRB
GeneCards (Weizmann)LILRB3
Ensembl hg19 (Hinxton)ENSG00000204577 [Gene_View]  chr19:54720147-54746711 [Contig_View]  LILRB3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000204577 [Gene_View]  chr19:54720147-54746711 [Contig_View]  LILRB3 [Vega]
ICGC DataPortalENSG00000204577
TCGA cBioPortalLILRB3
AceView (NCBI)LILRB3
Genatlas (Paris)LILRB3
WikiGenes11025
SOURCE (Princeton)LILRB3
Genetics Home Reference (NIH)LILRB3
Genomic and cartography
GoldenPath hg19 (UCSC)LILRB3  -     chr19:54720147-54746711 -  19q13.42   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LILRB3  -     19q13.42   [Description]    (hg38-Dec_2013)
EnsemblLILRB3 - 19q13.42 [CytoView hg19]  LILRB3 - 19q13.42 [CytoView hg38]
Mapping of homologs : NCBILILRB3 [Mapview hg19]  LILRB3 [Mapview hg38]
OMIM604820   
Gene and transcription
Genbank (Entrez)AF000575 AF009632 AF009633 AF009634 AF009635
RefSeq transcript (Entrez)NM_001081450 NM_006864
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NT_187693 NW_004929415
Consensus coding sequences : CCDS (NCBI)LILRB3
Cluster EST : UnigeneHs.688335 [ NCBI ]
CGAP (NCI)Hs.688335
Alternative Splicing GalleryENSG00000204577
Gene ExpressionLILRB3 [ NCBI-GEO ]   LILRB3 [ EBI - ARRAY_EXPRESS ]   LILRB3 [ SEEK ]   LILRB3 [ MEM ]
Gene Expression Viewer (FireBrowse)LILRB3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11025
GTEX Portal (Tissue expression)LILRB3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75022   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75022  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75022
Splice isoforms : SwissVarO75022
PhosPhoSitePlusO75022
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)LILRB3
DMDM Disease mutations11025
Blocks (Seattle)LILRB3
SuperfamilyO75022
Human Protein AtlasENSG00000204577
Peptide AtlasO75022
HPRD11995
IPIIPI00376782   IPI00938185   IPI00972992   IPI00853187   IPI00879776   IPI00879613   IPI00893278   IPI00893140   IPI00893009   IPI00894058   
Protein Interaction databases
DIP (DOE-UCLA)O75022
IntAct (EBI)O75022
FunCoupENSG00000204577
BioGRIDLILRB3
STRING (EMBL)LILRB3
ZODIACLILRB3
Ontologies - Pathways
QuickGOO75022
Ontology : AmiGOimmune system process  receptor activity  transmembrane signaling receptor activity  protein binding  integral component of plasma membrane  defense response  cell surface receptor signaling pathway  negative regulation of osteoclast differentiation  
Ontology : EGO-EBIimmune system process  receptor activity  transmembrane signaling receptor activity  protein binding  integral component of plasma membrane  defense response  cell surface receptor signaling pathway  negative regulation of osteoclast differentiation  
Pathways : KEGGOsteoclast differentiation    B cell receptor signaling pathway   
NDEx NetworkLILRB3
Atlas of Cancer Signalling NetworkLILRB3
Wikipedia pathwaysLILRB3
Orthology - Evolution
OrthoDB11025
GeneTree (enSembl)ENSG00000204577
Phylogenetic Trees/Animal Genes : TreeFamLILRB3
HOVERGENO75022
HOGENOMO75022
Homologs : HomoloGeneLILRB3
Homology/Alignments : Family Browser (UCSC)LILRB3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLILRB3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LILRB3
dbVarLILRB3
ClinVarLILRB3
1000_GenomesLILRB3 
Exome Variant ServerLILRB3
ExAC (Exome Aggregation Consortium)LILRB3 (select the gene name)
Genetic variants : HAPMAP11025
Genomic Variants (DGV)LILRB3 [DGVbeta]
DECIPHER (Syndromes)19:54720147-54746711  ENSG00000204577
CONAN: Copy Number AnalysisLILRB3 
Mutations
ICGC Data PortalLILRB3 
TCGA Data PortalLILRB3 
Broad Tumor PortalLILRB3
OASIS PortalLILRB3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLILRB3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLILRB3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LILRB3
DgiDB (Drug Gene Interaction Database)LILRB3
DoCM (Curated mutations)LILRB3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LILRB3 (select a term)
intoGenLILRB3
Cancer3DLILRB3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604820   
Orphanet
MedgenLILRB3
Genetic Testing Registry LILRB3
NextProtO75022 [Medical]
TSGene11025
GENETestsLILRB3
Huge Navigator LILRB3 [HugePedia]
snp3D : Map Gene to Disease11025
BioCentury BCIQLILRB3
ClinGenLILRB3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11025
Chemical/Pharm GKB GenePA30381
Clinical trialLILRB3
Miscellaneous
canSAR (ICR)LILRB3 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLILRB3
EVEXLILRB3
GoPubMedLILRB3
iHOPLILRB3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:11:03 CET 2017

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