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LZTS2 (leucine zipper tumor suppressor 2)

Identity

Alias_namesleucine zipper
Alias_symbol (synonym)KIAA1813
LAPSER1
Other alias
HGNC (Hugo) LZTS2
LocusID (NCBI) 84445
Atlas_Id 41223
Location 10q24.31  [Link to chromosome band 10q24]
Location_base_pair Starts at 100998349 and ends at 101007836 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LZTS2 (10q24.31) / LZTS2 (10q24.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LZTS2   29381
Cards
Entrez_Gene (NCBI)LZTS2  84445  leucine zipper tumor suppressor 2
AliasesLAPSER1
GeneCards (Weizmann)LZTS2
Ensembl hg19 (Hinxton)ENSG00000107816 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107816 [Gene_View]  chr10:100998349-101007836 [Contig_View]  LZTS2 [Vega]
ICGC DataPortalENSG00000107816
TCGA cBioPortalLZTS2
AceView (NCBI)LZTS2
Genatlas (Paris)LZTS2
WikiGenes84445
SOURCE (Princeton)LZTS2
Genetics Home Reference (NIH)LZTS2
Genomic and cartography
GoldenPath hg38 (UCSC)LZTS2  -     chr10:100998349-101007836 +  10q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LZTS2  -     10q24.31   [Description]    (hg19-Feb_2009)
EnsemblLZTS2 - 10q24.31 [CytoView hg19]  LZTS2 - 10q24.31 [CytoView hg38]
Mapping of homologs : NCBILZTS2 [Mapview hg19]  LZTS2 [Mapview hg38]
OMIM610454   
Gene and transcription
Genbank (Entrez)AB058716 AK097997 AK298208 AL834338 AY029201
RefSeq transcript (Entrez)NM_001318099 NM_001318100 NM_001318101 NM_032429
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LZTS2
Cluster EST : UnigeneHs.734981 [ NCBI ]
CGAP (NCI)Hs.734981
Alternative Splicing GalleryENSG00000107816
Gene ExpressionLZTS2 [ NCBI-GEO ]   LZTS2 [ EBI - ARRAY_EXPRESS ]   LZTS2 [ SEEK ]   LZTS2 [ MEM ]
Gene Expression Viewer (FireBrowse)LZTS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84445
GTEX Portal (Tissue expression)LZTS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BRK4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BRK4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BRK4
Splice isoforms : SwissVarQ9BRK4
PhosPhoSitePlusQ9BRK4
Domains : Interpro (EBI)LZTS2   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)LZTS2
DMDM Disease mutations84445
Blocks (Seattle)LZTS2
SuperfamilyQ9BRK4
Human Protein AtlasENSG00000107816
Peptide AtlasQ9BRK4
HPRD14341
IPIIPI00101927   IPI00643543   IPI00642922   IPI00646345   
Protein Interaction databases
DIP (DOE-UCLA)Q9BRK4
IntAct (EBI)Q9BRK4
FunCoupENSG00000107816
BioGRIDLZTS2
STRING (EMBL)LZTS2
ZODIACLZTS2
Ontologies - Pathways
QuickGOQ9BRK4
Ontology : AmiGOkidney development  protein binding  microtubule organizing center  cytosol  microtubule  plasma membrane  cell cycle  negative regulation of cell proliferation  Wnt signaling pathway  vesicle  cell division  negative regulation of canonical Wnt signaling pathway  negative regulation of protein localization to nucleus  
Ontology : EGO-EBIkidney development  protein binding  microtubule organizing center  cytosol  microtubule  plasma membrane  cell cycle  negative regulation of cell proliferation  Wnt signaling pathway  vesicle  cell division  negative regulation of canonical Wnt signaling pathway  negative regulation of protein localization to nucleus  
NDEx NetworkLZTS2
Atlas of Cancer Signalling NetworkLZTS2
Wikipedia pathwaysLZTS2
Orthology - Evolution
OrthoDB84445
GeneTree (enSembl)ENSG00000107816
Phylogenetic Trees/Animal Genes : TreeFamLZTS2
HOVERGENQ9BRK4
HOGENOMQ9BRK4
Homologs : HomoloGeneLZTS2
Homology/Alignments : Family Browser (UCSC)LZTS2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLZTS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LZTS2
dbVarLZTS2
ClinVarLZTS2
1000_GenomesLZTS2 
Exome Variant ServerLZTS2
ExAC (Exome Aggregation Consortium)LZTS2 (select the gene name)
Genetic variants : HAPMAP84445
Genomic Variants (DGV)LZTS2 [DGVbeta]
DECIPHERLZTS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLZTS2 
Mutations
ICGC Data PortalLZTS2 
TCGA Data PortalLZTS2 
Broad Tumor PortalLZTS2
OASIS PortalLZTS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLZTS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLZTS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LZTS2
DgiDB (Drug Gene Interaction Database)LZTS2
DoCM (Curated mutations)LZTS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LZTS2 (select a term)
intoGenLZTS2
Cancer3DLZTS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610454   
Orphanet
MedgenLZTS2
Genetic Testing Registry LZTS2
NextProtQ9BRK4 [Medical]
TSGene84445
GENETestsLZTS2
Huge Navigator LZTS2 [HugePedia]
snp3D : Map Gene to Disease84445
BioCentury BCIQLZTS2
ClinGenLZTS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84445
Chemical/Pharm GKB GenePA134944540
Clinical trialLZTS2
Miscellaneous
canSAR (ICR)LZTS2 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLZTS2
EVEXLZTS2
GoPubMedLZTS2
iHOPLZTS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:23:46 CEST 2017

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