Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

M6PR (mannose-6-phosphate receptor, cation dependent)

Identity

Alias_namesmannose-6-phosphate receptor (cation dependent)
Alias_symbol (synonym)CD-MPR
CD-M6PR
Other aliasMPR 46
MPR-46
MPR46
SMPR
HGNC (Hugo) M6PR
LocusID (NCBI) 4074
Atlas_Id 46022
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 8940361 and ends at 8949761 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)M6PR   6752
Cards
Entrez_Gene (NCBI)M6PR  4074  mannose-6-phosphate receptor, cation dependent
AliasesCD-M6PR; CD-MPR; MPR; MPR-46; 
MPR46; SMPR
GeneCards (Weizmann)M6PR
Ensembl hg19 (Hinxton)ENSG00000003056 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000003056 [Gene_View]  chr12:8940361-8949761 [Contig_View]  M6PR [Vega]
ICGC DataPortalENSG00000003056
TCGA cBioPortalM6PR
AceView (NCBI)M6PR
Genatlas (Paris)M6PR
WikiGenes4074
SOURCE (Princeton)M6PR
Genetics Home Reference (NIH)M6PR
Genomic and cartography
GoldenPath hg38 (UCSC)M6PR  -     chr12:8940361-8949761 -  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)M6PR  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblM6PR - 12p13.31 [CytoView hg19]  M6PR - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBIM6PR [Mapview hg19]  M6PR [Mapview hg38]
OMIM154540   
Gene and transcription
Genbank (Entrez)AA648974 AK057556 AK222792 AK291143 AK312689
RefSeq transcript (Entrez)NM_001207024 NM_002355
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)M6PR
Cluster EST : UnigeneHs.744902 [ NCBI ]
CGAP (NCI)Hs.744902
Alternative Splicing GalleryENSG00000003056
Gene ExpressionM6PR [ NCBI-GEO ]   M6PR [ EBI - ARRAY_EXPRESS ]   M6PR [ SEEK ]   M6PR [ MEM ]
Gene Expression Viewer (FireBrowse)M6PR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4074
GTEX Portal (Tissue expression)M6PR
Human Protein AtlasENSG00000003056-M6PR [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20645   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20645  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20645
Splice isoforms : SwissVarP20645
PhosPhoSitePlusP20645
Domains : Interpro (EBI)Man-6-P_rcpt    Man-6-P_rcpt_cation_dep    Man6P_isomerase_rcpt-bd_dom   
Domain families : Pfam (Sanger)Man-6-P_recep (PF02157)   
Domain families : Pfam (NCBI)pfam02157   
Conserved Domain (NCBI)M6PR
DMDM Disease mutations4074
Blocks (Seattle)M6PR
PDB (SRS)1JUQ   
PDB (PDBSum)1JUQ   
PDB (IMB)1JUQ   
PDB (RSDB)1JUQ   
Structural Biology KnowledgeBase1JUQ   
SCOP (Structural Classification of Proteins)1JUQ   
CATH (Classification of proteins structures)1JUQ   
SuperfamilyP20645
Human Protein Atlas [tissue]ENSG00000003056-M6PR [tissue]
Peptide AtlasP20645
HPRD01106
IPIIPI00025049   IPI01012692   IPI01013109   IPI01013918   IPI01012535   IPI01011267   IPI01009828   IPI01012077   IPI01009358   IPI01009837   
Protein Interaction databases
DIP (DOE-UCLA)P20645
IntAct (EBI)P20645
FunCoupENSG00000003056
BioGRIDM6PR
STRING (EMBL)M6PR
ZODIACM6PR
Ontologies - Pathways
QuickGOP20645
Ontology : AmiGOtransmembrane signaling receptor activity  protein binding  mannose binding  lysosome  lysosomal membrane  endosome  late endosome  plasma membrane  integral component of plasma membrane  receptor-mediated endocytosis  signal transduction  endosome to lysosome transport  mannose transmembrane transporter activity  mannose transport  membrane  transport vesicle  clathrin-coated vesicle membrane  retromer complex  retromer complex  trans-Golgi network membrane  secretion of lysosomal enzymes  perinuclear region of cytoplasm  membrane organization  retromer complex binding  
Ontology : EGO-EBItransmembrane signaling receptor activity  protein binding  mannose binding  lysosome  lysosomal membrane  endosome  late endosome  plasma membrane  integral component of plasma membrane  receptor-mediated endocytosis  signal transduction  endosome to lysosome transport  mannose transmembrane transporter activity  mannose transport  membrane  transport vesicle  clathrin-coated vesicle membrane  retromer complex  retromer complex  trans-Golgi network membrane  secretion of lysosomal enzymes  perinuclear region of cytoplasm  membrane organization  retromer complex binding  
Pathways : KEGGLysosome    Phagosome   
NDEx NetworkM6PR
Atlas of Cancer Signalling NetworkM6PR
Wikipedia pathwaysM6PR
Orthology - Evolution
OrthoDB4074
GeneTree (enSembl)ENSG00000003056
Phylogenetic Trees/Animal Genes : TreeFamM6PR
HOVERGENP20645
HOGENOMP20645
Homologs : HomoloGeneM6PR
Homology/Alignments : Family Browser (UCSC)M6PR
Gene fusions - Rearrangements
Tumor Fusion PortalM6PR
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerM6PR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)M6PR
dbVarM6PR
ClinVarM6PR
1000_GenomesM6PR 
Exome Variant ServerM6PR
ExAC (Exome Aggregation Consortium)ENSG00000003056
GNOMAD BrowserENSG00000003056
Genetic variants : HAPMAP4074
Genomic Variants (DGV)M6PR [DGVbeta]
DECIPHERM6PR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisM6PR 
Mutations
ICGC Data PortalM6PR 
TCGA Data PortalM6PR 
Broad Tumor PortalM6PR
OASIS PortalM6PR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICM6PR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDM6PR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch M6PR
DgiDB (Drug Gene Interaction Database)M6PR
DoCM (Curated mutations)M6PR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)M6PR (select a term)
intoGenM6PR
Cancer3DM6PR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM154540   
Orphanet
DisGeNETM6PR
MedgenM6PR
Genetic Testing Registry M6PR
NextProtP20645 [Medical]
TSGene4074
GENETestsM6PR
Target ValidationM6PR
Huge Navigator M6PR [HugePedia]
snp3D : Map Gene to Disease4074
BioCentury BCIQM6PR
ClinGenM6PR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4074
Chemical/Pharm GKB GenePA30513
Clinical trialM6PR
Miscellaneous
canSAR (ICR)M6PR (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineM6PR
EVEXM6PR
GoPubMedM6PR
iHOPM6PR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:21:13 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.