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MAEL (maelstrom spermatogenic transposon silencer)

Identity

Alias_namesmaelstrom homolog (Drosophila)
Alias_symbol (synonym)FLJ14904
CT128
SPATA35
Other alias
HGNC (Hugo) MAEL
LocusID (NCBI) 84944
Atlas_Id 51735
Location 1q24.1  [Link to chromosome band 1q24]
Location_base_pair Starts at 166989089 and ends at 167022212 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
UBE2Q1 (1q21.3) / MAEL (1q24.1)UBE2Q1 1q21.3 / MAEL 1q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MAEL   25929
Cards
Entrez_Gene (NCBI)MAEL  84944  maelstrom spermatogenic transposon silencer
AliasesCT128; SPATA35
GeneCards (Weizmann)MAEL
Ensembl hg19 (Hinxton)ENSG00000143194 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143194 [Gene_View]  chr1:166989089-167022212 [Contig_View]  MAEL [Vega]
ICGC DataPortalENSG00000143194
TCGA cBioPortalMAEL
AceView (NCBI)MAEL
Genatlas (Paris)MAEL
WikiGenes84944
SOURCE (Princeton)MAEL
Genetics Home Reference (NIH)MAEL
Genomic and cartography
GoldenPath hg38 (UCSC)MAEL  -     chr1:166989089-167022212 +  1q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAEL  -     1q24.1   [Description]    (hg19-Feb_2009)
EnsemblMAEL - 1q24.1 [CytoView hg19]  MAEL - 1q24.1 [CytoView hg38]
Mapping of homologs : NCBIMAEL [Mapview hg19]  MAEL [Mapview hg38]
OMIM611368   
Gene and transcription
Genbank (Entrez)AK027810 AK131066 AK302253 AL133073 BC028595
RefSeq transcript (Entrez)NM_001286377 NM_001286378 NM_032858
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAEL
Cluster EST : UnigeneHs.651245 [ NCBI ]
CGAP (NCI)Hs.651245
Alternative Splicing GalleryENSG00000143194
Gene ExpressionMAEL [ NCBI-GEO ]   MAEL [ EBI - ARRAY_EXPRESS ]   MAEL [ SEEK ]   MAEL [ MEM ]
Gene Expression Viewer (FireBrowse)MAEL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84944
GTEX Portal (Tissue expression)MAEL
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96JY0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96JY0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96JY0
Splice isoforms : SwissVarQ96JY0
PhosPhoSitePlusQ96JY0
Domains : Interpro (EBI)HMG_box_dom    Maelstrom   
Domain families : Pfam (Sanger)HMG_box_2 (PF09011)    Maelstrom (PF13017)   
Domain families : Pfam (NCBI)pfam09011    pfam13017   
Conserved Domain (NCBI)MAEL
DMDM Disease mutations84944
Blocks (Seattle)MAEL
PDB (SRS)2CTO   
PDB (PDBSum)2CTO   
PDB (IMB)2CTO   
PDB (RSDB)2CTO   
Structural Biology KnowledgeBase2CTO   
SCOP (Structural Classification of Proteins)2CTO   
CATH (Classification of proteins structures)2CTO   
SuperfamilyQ96JY0
Human Protein AtlasENSG00000143194
Peptide AtlasQ96JY0
HPRD08609
IPIIPI00064475   IPI00477136   IPI00923411   
Protein Interaction databases
DIP (DOE-UCLA)Q96JY0
IntAct (EBI)Q96JY0
FunCoupENSG00000143194
BioGRIDMAEL
STRING (EMBL)MAEL
ZODIACMAEL
Ontologies - Pathways
QuickGOQ96JY0
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  chromatin  cell morphogenesis  XY body  nucleus  nucleus  cytoplasm  synapsis  male meiotic nuclear division  multicellular organism development  spermatogenesis  spermatogenesis  intrinsic apoptotic signaling pathway in response to DNA damage  fertilization  cell differentiation  autosome  gene silencing by RNA  chromatoid body  piRNA metabolic process  piRNA metabolic process  DNA methylation involved in gamete generation  negative regulation of apoptotic process  P granule  P granule  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  regulation of organ growth  perinuclear region of cytoplasm  piP-body  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  chromatin  cell morphogenesis  XY body  nucleus  nucleus  cytoplasm  synapsis  male meiotic nuclear division  multicellular organism development  spermatogenesis  spermatogenesis  intrinsic apoptotic signaling pathway in response to DNA damage  fertilization  cell differentiation  autosome  gene silencing by RNA  chromatoid body  piRNA metabolic process  piRNA metabolic process  DNA methylation involved in gamete generation  negative regulation of apoptotic process  P granule  P granule  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  regulation of organ growth  perinuclear region of cytoplasm  piP-body  
NDEx NetworkMAEL
Atlas of Cancer Signalling NetworkMAEL
Wikipedia pathwaysMAEL
Orthology - Evolution
OrthoDB84944
GeneTree (enSembl)ENSG00000143194
Phylogenetic Trees/Animal Genes : TreeFamMAEL
HOVERGENQ96JY0
HOGENOMQ96JY0
Homologs : HomoloGeneMAEL
Homology/Alignments : Family Browser (UCSC)MAEL
Gene fusions - Rearrangements
Fusion : MitelmanUBE2Q1/MAEL [1q21.3/1q24.1]  [t(1;1)(q21;q24)]  
Fusion: TCGAUBE2Q1 1q21.3 MAEL 1q24.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAEL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAEL
dbVarMAEL
ClinVarMAEL
1000_GenomesMAEL 
Exome Variant ServerMAEL
ExAC (Exome Aggregation Consortium)MAEL (select the gene name)
Genetic variants : HAPMAP84944
Genomic Variants (DGV)MAEL [DGVbeta]
DECIPHERMAEL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAEL 
Mutations
ICGC Data PortalMAEL 
TCGA Data PortalMAEL 
Broad Tumor PortalMAEL
OASIS PortalMAEL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAEL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMAEL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MAEL
DgiDB (Drug Gene Interaction Database)MAEL
DoCM (Curated mutations)MAEL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAEL (select a term)
intoGenMAEL
Cancer3DMAEL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611368   
Orphanet
MedgenMAEL
Genetic Testing Registry MAEL
NextProtQ96JY0 [Medical]
TSGene84944
GENETestsMAEL
Target ValidationMAEL
Huge Navigator MAEL [HugePedia]
snp3D : Map Gene to Disease84944
BioCentury BCIQMAEL
ClinGenMAEL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84944
Chemical/Pharm GKB GenePA142671488
Clinical trialMAEL
Miscellaneous
canSAR (ICR)MAEL (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAEL
EVEXMAEL
GoPubMedMAEL
iHOPMAEL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:41:53 CEST 2017

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