MASP2 (mannan-binding lectin serine peptidase 2)

Identity

Other names	MAP19
	MASP-2
	sMAP
HGNC	MASP2
Location	1p36.3-p36.2
Location_base_pair	Starts at 11009167 and ends at 11029872 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	MASP2   6902
Entrez_Gene	MASP2  10747  mannan-binding lectin serine peptidase 2
	Cards
GeneCards	MASP2
Ensembl	MASP2 [Search_View]   ENSG00000009724 [Gene_View]
Genatlas	MASP2
GeneLynx	MASP2
eGenome	MASP2
euGene	10747
	Genomic and cartography
GoldenPath	MASP2  -     chr1:11009167-11029872 -  1p36.22   [Description]    (hg18-March_2006)
Ensembl	MASP2 - 1p36.22 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	MASP2
	Gene and transcription
Genbank	AB008047 [ ENTREZ ]
Genbank	AK290823 [ ENTREZ ]
Genbank	BC052299 [ ENTREZ ]
Genbank	BC067359 [ ENTREZ ]
Genbank	BC080556 [ ENTREZ ]
RefSeq	NM_006610 [ SRS ]    NM_006610 [ ENTREZ ]
RefSeq	NM_139208 [ SRS ]    NM_139208 [ ENTREZ ]
RefSeq	AC_000044 [ SRS ]    AC_000044 [ ENTREZ ]
RefSeq	AC_000133 [ SRS ]    AC_000133 [ ENTREZ ]
RefSeq	NC_000001 [ SRS ]    NC_000001 [ ENTREZ ]
RefSeq	NG_007289 [ SRS ]    NG_007289 [ ENTREZ ]
RefSeq	NT_021937 [ SRS ]    NT_021937 [ ENTREZ ]
RefSeq	NW_001838534 [ SRS ]    NW_001838534 [ ENTREZ ]
RefSeq	NW_923572 [ SRS ]    NW_923572 [ ENTREZ ]
AceView	MASP2 AceView - NCBI
Unigene	Hs.655645 [ SRS ]    Hs.655645 [ NCBI ]     HS655645 [ spliceNest ]
Fast-db	4883 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O00187 [ SRS]    O00187 [ EXPASY ]     O00187 [ INTERPRO ]     O00187 [ UNIPROT ]
Prosite	PS00010 ASX_HYDROXYL [ SRS ]    PS00010 ASX_HYDROXYL [ Expasy ]
Prosite	PS01180 CUB [ SRS ]    PS01180 CUB [ Expasy ]
Prosite	PS00022 EGF_1 [ SRS ]    PS00022 EGF_1 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS50026 EGF_3 [ SRS ]    PS50026 EGF_3 [ Expasy ]
Prosite	PS01187 EGF_CA [ SRS ]    PS01187 EGF_CA [ Expasy ]
Prosite	PS50923 SUSHI [ SRS ]    PS50923 SUSHI [ Expasy ]
Prosite	PS50240 TRYPSIN_DOM [ SRS ]    PS50240 TRYPSIN_DOM [ Expasy ]
Prosite	PS00134 TRYPSIN_HIS [ SRS ]    PS00134 TRYPSIN_HIS [ Expasy ]
Prosite	PS00135 TRYPSIN_SER [ SRS ]    PS00135 TRYPSIN_SER [ Expasy ]
Interpro	IPR016060 Complement_control_module [ SRS ]    IPR016060 Complement_control_module [ EBI ]
Interpro	IPR000859 CUB [ SRS ]    IPR000859 CUB [ EBI ]
Interpro	IPR000152 EGF-type_Asp/Asn_hydroxyl_CS [ SRS ]    IPR000152 EGF-type_Asp/Asn_hydroxyl_CS [ EBI ]
Interpro	IPR000742 EGF_3 [ SRS ]    IPR000742 EGF_3 [ EBI ]
Interpro	IPR001881 EGF_Ca_bd [ SRS ]    IPR001881 EGF_Ca_bd [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR001254 Peptidase_S1_S6 [ SRS ]    IPR001254 Peptidase_S1_S6 [ EBI ]
Interpro	IPR001314 Peptidase_S1A [ SRS ]    IPR001314 Peptidase_S1A [ EBI ]
Interpro	IPR000436 Sushi_SCR_CCP [ SRS ]    IPR000436 Sushi_SCR_CCP [ EBI ]
CluSTr	O00187
Pfam	PF00431 CUB [ SRS ]    PF00431 CUB [ Sanger ]    pfam00431 [ NCBI-CDD ]
Pfam	PF00084 Sushi [ SRS ]    PF00084 Sushi [ Sanger ]    pfam00084 [ NCBI-CDD ]
Pfam	PF00089 Trypsin [ SRS ]    PF00089 Trypsin [ Sanger ]    pfam00089 [ NCBI-CDD ]
Smart	SM00032 CCP [EMBL]
Smart	SM00042 CUB [EMBL]
Smart	SM00179 EGF_CA [EMBL]
Smart	SM00020 Tryp_SPc [EMBL]
Blocks	O00187
PDB	1Q3X [ SRS ]    1Q3X [ PdbSum ],   1Q3X [ IMB ]   1Q3X [ RSDB ]
PDB	1SZB [ SRS ]    1SZB [ PdbSum ],   1SZB [ IMB ]   1SZB [ RSDB ]
PDB	1ZJK [ SRS ]    1ZJK [ PdbSum ],   1ZJK [ IMB ]   1ZJK [ RSDB ]
HPRD	05484
	Protein Interaction databases
DIP	O00187
IntAct	O00187
	Polymorphism : SNP, mutations, diseases
OMIM	605102    [ map ]
GENECLINICS	605102
SNP	MASP2 [dbSNP-NCBI]
SNP	NM_006610 [SNP-NCI]
SNP	NM_139208 [SNP-NCI]
SNP	MASP2 [GeneSNPs - Utah]  MASP2] [HGBASE - SRS]
HAPMAP	MASP2 [HAPMAP]
HGMD	MASP2
	General knowledge
Family Browser	MASP2 [UCSC Family Browser]
SOURCE	NM_006610
SOURCE	NM_139208
SMD	Hs.655645
SAGE	Hs.655645
Enzyme	3.4.21.104 [ Enzyme-Expasy ]   3.4.21.104 [ Enzyme-SRS ]   3.4.21.104 [ IntEnz-EBI ]   3.4.21.104 [ BRENDA ]   3.4.21.104 [ KEGG ]   3.4.21.104 [ WIT ]
GO	complement activation, lectin pathway [Amigo]  complement activation, lectin pathway
GO	serine-type endopeptidase activity [Amigo]  serine-type endopeptidase activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	extracellular region [Amigo]  extracellular region
GO	extracellular region [Amigo]  extracellular region
GO	proteolysis [Amigo]  proteolysis
GO	complement activation, classical pathway [Amigo]  complement activation, classical pathway
BIOCARTA	Complement Pathway    [Genes]
BIOCARTA	Lectin Induced Complement Pathway    [Genes]
KEGG	Complement and coagulation cascades
PubGene	MASP2
TreeFam	MASP2
CTD	10747 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	MASP2 Related clones (RZPD - Berlin)
	PubMed
PubMed	38 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:20:59 2008