Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10747
MIM: 605102
HGNC: 6902
Ensembl: ENSG00000009724
Variants:
dbSNP: 10747
ClinVar: 10747
TCGA: ENSG00000009724
COSMIC: MASP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000009724 | ENST00000400897 | O00187 |
| ENSG00000009724 | ENST00000400898 | O00187 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35816998 | 2023 | Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19. | 4 |
| 36574978 | 2023 | Ficolin-3 and MASP-2 gene variants in Siberian arctic populations: Summarized evidence of selective pressure for the high frequency of lectin complement pathway deficiency. | 0 |
| 36805857 | 2023 | l-ficolin-MASP arm of the complement system in schizophrenia. | 1 |
| 37191586 | 2023 | MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence. | 2 |
| 37204457 | 2023 | Mannose-binding lectin gene 2 variant DD (rs 5030737) is associated with susceptibility to COVID-19 infection in the urban population of Patna City (India). | 1 |
| 35816998 | 2023 | Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19. | 4 |
| 36574978 | 2023 | Ficolin-3 and MASP-2 gene variants in Siberian arctic populations: Summarized evidence of selective pressure for the high frequency of lectin complement pathway deficiency. | 0 |
| 36805857 | 2023 | l-ficolin-MASP arm of the complement system in schizophrenia. | 1 |
| 37191586 | 2023 | MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence. | 2 |
| 37204457 | 2023 | Mannose-binding lectin gene 2 variant DD (rs 5030737) is associated with susceptibility to COVID-19 infection in the urban population of Patna City (India). | 1 |
| 35483450 | 2022 | Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. | 2 |
| 35861070 | 2022 | High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism. | 3 |
| 35924689 | 2022 | Mannose binding lectin-associated serine protease 2 (MASP2) gene polymorphism and susceptibility to human T-lymphotropic virus type 1 (HTLV-1) infection in blood donors from Mashhad, Iran. | 1 |
| 36149051 | 2022 | Significance of Mannan Binding Lectin-Associated Serine Protease 2 in Urinary Extracellular Vesicles in IgA Nephropathy. | 2 |
| 36153401 | 2022 | Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel. | 1 |
Citation
Dessen P
MASP2 (MBL associated serine protease 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46101/masp2
