MBD1 (methyl-CpG binding domain protein 1)

Identity

Other names	CXXC3
	PCM1
	RFT
Hugo	MBD1
Location	18q21
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

Breakpoints

External links

	Nomenclature
Hugo	MBD1
GDB	MBD1
Entrez_Gene	MBD1  4152  methyl-CpG binding domain protein 1
	Cards
GeneCards	MBD1
Ensembl	MBD1 [Search_View]   ENSG00000141644 [Gene_View]
Genatlas	MBD1
GeneLynx	MBD1
eGenome	MBD1
euGene	4152
	Genomic and cartography
GoldenPath	MBD1  -  18q21   chr18:46049214-46062142 -  18q21.1   [Description]    (hg18-March_2006)
Ensembl	MBD1 - 18q21.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	MBD1
	Gene and transcription
Genbank	AB209765 [ ENTREZ ]
Genbank	AF072241 [ ENTREZ ]
Genbank	AF078830 [ ENTREZ ]
Genbank	AF078831 [ ENTREZ ]
Genbank	AF078832 [ ENTREZ ]
RefSeq	NM_002384 [ SRS ]    NM_002384 [ ENTREZ ]
RefSeq	NM_015844 [ SRS ]    NM_015844 [ ENTREZ ]
RefSeq	NM_015845 [ SRS ]    NM_015845 [ ENTREZ ]
RefSeq	NM_015846 [ SRS ]    NM_015846 [ ENTREZ ]
RefSeq	NM_015847 [ SRS ]    NM_015847 [ ENTREZ ]
RefSeq	AC_000061 [ SRS ]    AC_000061 [ ENTREZ ]
RefSeq	NC_000018 [ SRS ]    NC_000018 [ ENTREZ ]
RefSeq	NT_010966 [ SRS ]    NT_010966 [ ENTREZ ]
RefSeq	NW_927106 [ SRS ]    NW_927106 [ ENTREZ ]
AceView	MBD1 AceView - NCBI
Unigene	Hs.405610 [ SRS ]    Hs.405610 [ NCBI ]     HS405610 [ spliceNest ]
Fast-db	4431 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9UIS9 [ SRS]    Q9UIS9 [ EXPASY ]     Q9UIS9 [ INTERPRO ]
Prosite	PS50982 MBD [ SRS ]    PS50982 MBD [ Expasy ]
Prosite	PS51058 ZF_CXXC [ SRS ]    PS51058 ZF_CXXC [ Expasy ]
Interpro	IPR001739 Methyl_CpG_DNA-bd [ SRS ]    IPR001739 Methyl_CpG_DNA-bd [ EBI ]
Interpro	IPR002857 Znf_CXXC [ SRS ]    IPR002857 Znf_CXXC [ EBI ]
CluSTr	Q9UIS9
Pfam	PF01429 MBD [ SRS ]    PF01429 MBD [ Sanger ]    pfam01429 [ NCBI-CDD ]
Pfam	PF02008 zf-CXXC [ SRS ]    PF02008 zf-CXXC [ Sanger ]    pfam02008 [ NCBI-CDD ]
Smart	SM00391 MBD [EMBL]
Blocks	Q9UIS9
PDB	1D9N [ SRS ]    1D9N [ PdbSum ],   1D9N [ IMB ]   1D9N [ RSDB ]
PDB	1IG4 [ SRS ]    1IG4 [ PdbSum ],   1IG4 [ IMB ]   1IG4 [ RSDB ]
HPRD	01133
	Protein Interaction databases
DIP	Q9UIS9
IntAct	Q9UIS9
	Polymorphism : SNP, mutations, diseases
OMIM	156535    [ map ]
GENECLINICS	156535
SNP	MBD1 [dbSNP-NCBI]
SNP	NM_002384 [SNP-NCI]
SNP	NM_015844 [SNP-NCI]
SNP	NM_015845 [SNP-NCI]
SNP	NM_015846 [SNP-NCI]
SNP	NM_015847 [SNP-NCI]
SNP	MBD1 [GeneSNPs - Utah]  MBD1] [HGBASE - SRS]
HAPMAP	MBD1 [HAPMAP]
COSMIC	MBD1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	MBD1
	General knowledge
Family Browser	MBD1 [UCSC Family Browser]
SOURCE	NM_002384
SOURCE	NM_015844
SOURCE	NM_015845
SOURCE	NM_015846
SOURCE	NM_015847
SMD	Hs.405610
SAGE	Hs.405610
GO	transcription factor activity [Amigo]  transcription factor activity
GO	transcription corepressor activity [Amigo]  transcription corepressor activity
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	transcription [Amigo]  transcription
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	transcription from RNA polymerase II promoter [Amigo]  transcription from RNA polymerase II promoter
GO	zinc ion binding [Amigo]  zinc ion binding
GO	methyl-CpG binding [Amigo]  methyl-CpG binding
GO	negative regulation of transcription [Amigo]  negative regulation of transcription
GO	nuclear speck [Amigo]  nuclear speck
GO	metal ion binding [Amigo]  metal ion binding
PubGene	MBD1
TreeFam	MBD1
CTD	4152 [Comparative Genomics Database]
	Other databases
	Probes
Probe	MBD1 Related clones (RZPD - Berlin)
	PubMed
PubMed	36 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:16:14 2008