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MGST3 (microsomal glutathione S-transferase 3)

Identity

Alias_symbol (synonym)GST-III
Other alias
HGNC (Hugo) MGST3
LocusID (NCBI) 4259
Atlas_Id 68971
Location 1q24.1  [Link to chromosome band 1q24]
Location_base_pair Starts at 165630873 and ends at 165656135 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MGST3 (1q24.1) / SPOP (17q21.33)MGST3 (1q24.1) / TRAPPC6A (19q13.32)MGST3 (1q24.1) / ZMAT5 (22q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MGST3   7064
Cards
Entrez_Gene (NCBI)MGST3  4259  microsomal glutathione S-transferase 3
AliasesGST-III
GeneCards (Weizmann)MGST3
Ensembl hg19 (Hinxton)ENSG00000143198 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143198 [Gene_View]  chr1:165630873-165656135 [Contig_View]  MGST3 [Vega]
ICGC DataPortalENSG00000143198
TCGA cBioPortalMGST3
AceView (NCBI)MGST3
Genatlas (Paris)MGST3
WikiGenes4259
SOURCE (Princeton)MGST3
Genetics Home Reference (NIH)MGST3
Genomic and cartography
GoldenPath hg38 (UCSC)MGST3  -     chr1:165630873-165656135 +  1q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MGST3  -     1q24.1   [Description]    (hg19-Feb_2009)
EnsemblMGST3 - 1q24.1 [CytoView hg19]  MGST3 - 1q24.1 [CytoView hg38]
Mapping of homologs : NCBIMGST3 [Mapview hg19]  MGST3 [Mapview hg38]
OMIM604564   
Gene and transcription
Genbank (Entrez)AF026977 AI591182 AK223012 AK312103 BC000505
RefSeq transcript (Entrez)NM_004528
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MGST3
Cluster EST : UnigeneHs.732686 [ NCBI ]
CGAP (NCI)Hs.732686
Alternative Splicing GalleryENSG00000143198
Gene ExpressionMGST3 [ NCBI-GEO ]   MGST3 [ EBI - ARRAY_EXPRESS ]   MGST3 [ SEEK ]   MGST3 [ MEM ]
Gene Expression Viewer (FireBrowse)MGST3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4259
GTEX Portal (Tissue expression)MGST3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14880   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14880  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14880
Splice isoforms : SwissVarO14880
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
PhosPhoSitePlusO14880
Domains : Interpro (EBI)MAPEG-like_dom    Membr-assoc_MAPEG   
Domain families : Pfam (Sanger)MAPEG (PF01124)   
Domain families : Pfam (NCBI)pfam01124   
Conserved Domain (NCBI)MGST3
DMDM Disease mutations4259
Blocks (Seattle)MGST3
SuperfamilyO14880
Human Protein AtlasENSG00000143198
Peptide AtlasO14880
HPRD05192
IPIIPI00024266   IPI00639812   IPI00647044   
Protein Interaction databases
DIP (DOE-UCLA)O14880
IntAct (EBI)O14880
FunCoupENSG00000143198
BioGRIDMGST3
STRING (EMBL)MGST3
ZODIACMGST3
Ontologies - Pathways
QuickGOO14880
Ontology : AmiGOglutathione transferase activity  glutathione transferase activity  peroxidase activity  glutathione peroxidase activity  protein binding  nuclear envelope  endoplasmic reticulum  endoplasmic reticulum membrane  lipid metabolic process  xenobiotic metabolic process  signal transduction  response to organonitrogen compound  membrane  integral component of membrane  organelle membrane  intracellular membrane-bounded organelle  extracellular exosome  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  glutathione transferase activity  peroxidase activity  glutathione peroxidase activity  protein binding  nuclear envelope  endoplasmic reticulum  endoplasmic reticulum membrane  lipid metabolic process  xenobiotic metabolic process  signal transduction  response to organonitrogen compound  membrane  integral component of membrane  organelle membrane  intracellular membrane-bounded organelle  extracellular exosome  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkMGST3
Atlas of Cancer Signalling NetworkMGST3
Wikipedia pathwaysMGST3
Orthology - Evolution
OrthoDB4259
GeneTree (enSembl)ENSG00000143198
Phylogenetic Trees/Animal Genes : TreeFamMGST3
HOVERGENO14880
HOGENOMO14880
Homologs : HomoloGeneMGST3
Homology/Alignments : Family Browser (UCSC)MGST3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMGST3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MGST3
dbVarMGST3
ClinVarMGST3
1000_GenomesMGST3 
Exome Variant ServerMGST3
ExAC (Exome Aggregation Consortium)MGST3 (select the gene name)
Genetic variants : HAPMAP4259
Genomic Variants (DGV)MGST3 [DGVbeta]
DECIPHERMGST3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMGST3 
Mutations
ICGC Data PortalMGST3 
TCGA Data PortalMGST3 
Broad Tumor PortalMGST3
OASIS PortalMGST3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMGST3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMGST3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MGST3
DgiDB (Drug Gene Interaction Database)MGST3
DoCM (Curated mutations)MGST3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MGST3 (select a term)
intoGenMGST3
Cancer3DMGST3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604564   
Orphanet
MedgenMGST3
Genetic Testing Registry MGST3
NextProtO14880 [Medical]
TSGene4259
GENETestsMGST3
Target ValidationMGST3
Huge Navigator MGST3 [HugePedia]
snp3D : Map Gene to Disease4259
BioCentury BCIQMGST3
ClinGenMGST3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4259
Chemical/Pharm GKB GenePA30793
Clinical trialMGST3
Miscellaneous
canSAR (ICR)MGST3 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMGST3
EVEXMGST3
GoPubMedMGST3
iHOPMGST3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:26:08 CEST 2017

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