MGST3 (microsomal glutathione S-transferase 3)

2014-11-01 Affiliation

Identity

HGNC

MGST3

LOCATION

1q24.1

LOCUSID

4259

ALIAS

GST-III

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 4259
MIM: 604564
HGNC: 7064
Ensembl: ENSG00000143198

Variants:

dbSNP: 4259
ClinVar: 4259
TCGA: ENSG00000143198
COSMIC: MGST3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000143198	ENST00000367883	Q5VV89
ENSG00000143198	ENST00000367884	O14880
ENSG00000143198	ENST00000367884	A0A024R8Z1
ENSG00000143198	ENST00000367885	Q5VV89
ENSG00000143198	ENST00000367888	Q5VV87
ENSG00000143198	ENST00000367889	O14880
ENSG00000143198	ENST00000367889	A0A024R8Z1
ENSG00000143198	ENST00000627653	Q5VV89

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Glutathione metabolism	KEGG	ko00480
Metabolism of xenobiotics by cytochrome P450	KEGG	ko00980
Drug metabolism - cytochrome P450	KEGG	ko00982
Glutathione metabolism	KEGG	hsa00480
Metabolism of xenobiotics by cytochrome P450	KEGG	hsa00980
Drug metabolism - cytochrome P450	KEGG	hsa00982
Chemical carcinogenesis	KEGG	hsa05204
Chemical carcinogenesis	KEGG	ko05204
Metabolism	REACTOME	R-HSA-1430728
Biological oxidations	REACTOME	R-HSA-211859
Phase II conjugation	REACTOME	R-HSA-156580
Glutathione conjugation	REACTOME	R-HSA-156590
Aflatoxin activation and detoxification	REACTOME	R-HSA-5423646
Platinum drug resistance	KEGG	ko01524
Platinum drug resistance	KEGG	hsa01524
Fluid shear stress and atherosclerosis	KEGG	ko05418
Fluid shear stress and atherosclerosis	KEGG	hsa05418

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
19536175	2009	Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.	30
19064610	2009	Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.	16
25280473	2014	Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease.	16
19343046	2009	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	3

Citation

Dessen P

MGST3 (microsomal glutathione S-transferase 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68971/mgst3