Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MRAS (muscle RAS oncogene homolog)

Identity

Alias_symbol (synonym)M-RAs
R-RAS3
RRAS3
Other alias
HGNC (Hugo) MRAS
LocusID (NCBI) 22808
Atlas_Id 41425
Location 3q22.3  [Link to chromosome band 3q22]
Location_base_pair Starts at 138348666 and ends at 138405535 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LMNA (1q22) / MRAS (3q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRAS   7227
Cards
Entrez_Gene (NCBI)MRAS  22808  muscle RAS oncogene homolog
AliasesM-RAs; R-RAS3; RRAS3
GeneCards (Weizmann)MRAS
Ensembl hg19 (Hinxton)ENSG00000158186 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158186 [Gene_View]  chr3:138348666-138405535 [Contig_View]  MRAS [Vega]
ICGC DataPortalENSG00000158186
TCGA cBioPortalMRAS
AceView (NCBI)MRAS
Genatlas (Paris)MRAS
WikiGenes22808
SOURCE (Princeton)MRAS
Genetics Home Reference (NIH)MRAS
Genomic and cartography
GoldenPath hg38 (UCSC)MRAS  -     chr3:138348666-138405535 +  3q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRAS  -     3q22.3   [Description]    (hg19-Feb_2009)
EnsemblMRAS - 3q22.3 [CytoView hg19]  MRAS - 3q22.3 [CytoView hg38]
Mapping of homologs : NCBIMRAS [Mapview hg19]  MRAS [Mapview hg38]
OMIM608435   
Gene and transcription
Genbank (Entrez)AF022080 AF043938 AF493918 AI216578 AK056337
RefSeq transcript (Entrez)NM_001085049 NM_001252090 NM_001252091 NM_001252092 NM_001252093 NM_012219
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRAS
Cluster EST : UnigeneHs.735125 [ NCBI ]
CGAP (NCI)Hs.735125
Alternative Splicing GalleryENSG00000158186
Gene ExpressionMRAS [ NCBI-GEO ]   MRAS [ EBI - ARRAY_EXPRESS ]   MRAS [ SEEK ]   MRAS [ MEM ]
Gene Expression Viewer (FireBrowse)MRAS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22808
GTEX Portal (Tissue expression)MRAS
Human Protein AtlasENSG00000158186-MRAS [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14807   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14807  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14807
Splice isoforms : SwissVarO14807
PhosPhoSitePlusO14807
Domaine pattern : Prosite (Expaxy)RAS (PS51421)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Ras   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)MRAS
DMDM Disease mutations22808
Blocks (Seattle)MRAS
SuperfamilyO14807
Human Protein Atlas [tissue]ENSG00000158186-MRAS [tissue]
Peptide AtlasO14807
HPRD06662
IPIIPI00024166   IPI00816109   IPI00792754   IPI00791074   IPI00982726   
Protein Interaction databases
DIP (DOE-UCLA)O14807
IntAct (EBI)O14807
FunCoupENSG00000158186
BioGRIDMRAS
STRING (EMBL)MRAS
ZODIACMRAS
Ontologies - Pathways
QuickGOO14807
Ontology : AmiGOGTPase activity  protein binding  GTP binding  intracellular  plasma membrane  Ras protein signal transduction  multicellular organism development  muscle organ development  actin cytoskeleton organization  GTP-dependent protein binding  extracellular exosome  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  intracellular  plasma membrane  Ras protein signal transduction  multicellular organism development  muscle organ development  actin cytoskeleton organization  GTP-dependent protein binding  extracellular exosome  
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Rap1 signaling pathway    Tight junction    Regulation of actin cytoskeleton    HTLV-I infection    Proteoglycans in cancer   
NDEx NetworkMRAS
Atlas of Cancer Signalling NetworkMRAS
Wikipedia pathwaysMRAS
Orthology - Evolution
OrthoDB22808
GeneTree (enSembl)ENSG00000158186
Phylogenetic Trees/Animal Genes : TreeFamMRAS
HOVERGENO14807
HOGENOMO14807
Homologs : HomoloGeneMRAS
Homology/Alignments : Family Browser (UCSC)MRAS
Gene fusions - Rearrangements
Tumor Fusion PortalMRAS
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRAS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRAS
dbVarMRAS
ClinVarMRAS
1000_GenomesMRAS 
Exome Variant ServerMRAS
ExAC (Exome Aggregation Consortium)ENSG00000158186
GNOMAD BrowserENSG00000158186
Genetic variants : HAPMAP22808
Genomic Variants (DGV)MRAS [DGVbeta]
DECIPHERMRAS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRAS 
Mutations
ICGC Data PortalMRAS 
TCGA Data PortalMRAS 
Broad Tumor PortalMRAS
OASIS PortalMRAS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRAS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRAS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MRAS
DgiDB (Drug Gene Interaction Database)MRAS
DoCM (Curated mutations)MRAS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRAS (select a term)
intoGenMRAS
Cancer3DMRAS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608435   
Orphanet
DisGeNETMRAS
MedgenMRAS
Genetic Testing Registry MRAS
NextProtO14807 [Medical]
TSGene22808
GENETestsMRAS
Target ValidationMRAS
Huge Navigator MRAS [HugePedia]
snp3D : Map Gene to Disease22808
BioCentury BCIQMRAS
ClinGenMRAS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22808
Chemical/Pharm GKB GenePA30932
Clinical trialMRAS
Miscellaneous
canSAR (ICR)MRAS (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRAS
EVEXMRAS
GoPubMedMRAS
iHOPMRAS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:24:44 CET 2017

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