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NCAM2 (neural cell adhesion molecule 2)

Identity

Alias_symbol (synonym)NCAM21
MGC51008
Other alias
HGNC (Hugo) NCAM2
LocusID (NCBI) 4685
Atlas_Id 41504
Location 21q21.1  [Link to chromosome band 21q21]
Location_base_pair Starts at 22370633 and ends at 22912517 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CLDN11 (3q26.2) / NCAM2 (21q21.1)GNS (12q14.3) / NCAM2 (21q21.1)HNRNPF (10q11.21) / NCAM2 (21q21.1)
NCAM2 (21q21.1) / CRYL1 (13q12.11)NCAM2 (21q21.1) / GRIK1 (21q21.3)NCAM2 (21q21.1) / ILF2 (1q21.3)
NCAM2 (21q21.1) / PID1 (2q36.3)PDE7A (8q13.1) / NCAM2 (21q21.1)TEC (4p12) / NCAM2 (21q21.1)
TSPYL2 (Xp11.22) / NCAM2 (21q21.1)ZNF146 (19q13.12) / NCAM2 (21q21.1)NCAM2 21q21.1 / CRYL1 13q12.11
PDE7A 8q13.1 / NCAM2 21q21.1TEC - / NCAM2 21q21.1ZNF146 19q13.12 / NCAM2 21q21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NCAM2   7657
Cards
Entrez_Gene (NCBI)NCAM2  4685  neural cell adhesion molecule 2
AliasesNCAM21
GeneCards (Weizmann)NCAM2
Ensembl hg19 (Hinxton)ENSG00000154654 [Gene_View]  chr21:22370633-22912517 [Contig_View]  NCAM2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000154654 [Gene_View]  chr21:22370633-22912517 [Contig_View]  NCAM2 [Vega]
ICGC DataPortalENSG00000154654
TCGA cBioPortalNCAM2
AceView (NCBI)NCAM2
Genatlas (Paris)NCAM2
WikiGenes4685
SOURCE (Princeton)NCAM2
Genetics Home Reference (NIH)NCAM2
Genomic and cartography
GoldenPath hg19 (UCSC)NCAM2  -     chr21:22370633-22912517 +  21q21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NCAM2  -     21q21.1   [Description]    (hg38-Dec_2013)
EnsemblNCAM2 - 21q21.1 [CytoView hg19]  NCAM2 - 21q21.1 [CytoView hg38]
Mapping of homologs : NCBINCAM2 [Mapview hg19]  NCAM2 [Mapview hg38]
OMIM602040   
Gene and transcription
Genbank (Entrez)AA234378 AI207079 AK299054 AK302870 AL137344
RefSeq transcript (Entrez)NM_004540
RefSeq genomic (Entrez)NC_000021 NC_018932 NT_011512 NW_004929426
Consensus coding sequences : CCDS (NCBI)NCAM2
Cluster EST : UnigeneHs.473450 [ NCBI ]
CGAP (NCI)Hs.473450
Alternative Splicing GalleryENSG00000154654
Gene ExpressionNCAM2 [ NCBI-GEO ]   NCAM2 [ EBI - ARRAY_EXPRESS ]   NCAM2 [ SEEK ]   NCAM2 [ MEM ]
Gene Expression Viewer (FireBrowse)NCAM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4685
GTEX Portal (Tissue expression)NCAM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15394   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15394  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15394
Splice isoforms : SwissVarO15394
PhosPhoSitePlusO15394
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    IG_LIKE (PS50835)   
Domains : Interpro (EBI)FN3_dom    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub2    Neural_cell_adh   
Domain families : Pfam (Sanger)fn3 (PF00041)    I-set (PF07679)   
Domain families : Pfam (NCBI)pfam00041    pfam07679   
Domain families : Smart (EMBL)FN3 (SM00060)  IGc2 (SM00408)  
Conserved Domain (NCBI)NCAM2
DMDM Disease mutations4685
Blocks (Seattle)NCAM2
PDB (SRS)2DOC    2JLL    2KBG    2V5T    2VAJ    2WIM    2XY1    2XY2    2XYC   
PDB (PDBSum)2DOC    2JLL    2KBG    2V5T    2VAJ    2WIM    2XY1    2XY2    2XYC   
PDB (IMB)2DOC    2JLL    2KBG    2V5T    2VAJ    2WIM    2XY1    2XY2    2XYC   
PDB (RSDB)2DOC    2JLL    2KBG    2V5T    2VAJ    2WIM    2XY1    2XY2    2XYC   
Structural Biology KnowledgeBase2DOC    2JLL    2KBG    2V5T    2VAJ    2WIM    2XY1    2XY2    2XYC   
SCOP (Structural Classification of Proteins)2DOC    2JLL    2KBG    2V5T    2VAJ    2WIM    2XY1    2XY2    2XYC   
CATH (Classification of proteins structures)2DOC    2JLL    2KBG    2V5T    2VAJ    2WIM    2XY1    2XY2    2XYC   
SuperfamilyO15394
Human Protein AtlasENSG00000154654
Peptide AtlasO15394
HPRD03619
IPIIPI00376427   IPI00935147   IPI00922843   
Protein Interaction databases
DIP (DOE-UCLA)O15394
IntAct (EBI)O15394
FunCoupENSG00000154654
BioGRIDNCAM2
STRING (EMBL)NCAM2
ZODIACNCAM2
Ontologies - Pathways
QuickGOO15394
Ontology : AmiGOplasma membrane  neuron cell-cell adhesion  integral component of membrane  axon  
Ontology : EGO-EBIplasma membrane  neuron cell-cell adhesion  integral component of membrane  axon  
Pathways : KEGGCell adhesion molecules (CAMs)    Prion diseases   
NDEx NetworkNCAM2
Atlas of Cancer Signalling NetworkNCAM2
Wikipedia pathwaysNCAM2
Orthology - Evolution
OrthoDB4685
GeneTree (enSembl)ENSG00000154654
Phylogenetic Trees/Animal Genes : TreeFamNCAM2
HOVERGENO15394
HOGENOMO15394
Homologs : HomoloGeneNCAM2
Homology/Alignments : Family Browser (UCSC)NCAM2
Gene fusions - Rearrangements
Fusion : MitelmanNCAM2/CRYL1 [21q21.1/13q12.11]  
Fusion : MitelmanPDE7A/NCAM2 [8q13.1/21q21.1]  [t(8;21)(q13;q21)]  
Fusion : MitelmanTEC/NCAM2 [-/21q21.1]  [t(4;21)(p11;q21)]  
Fusion : MitelmanZNF146/NCAM2 [19q13.12/21q21.1]  [t(19;21)(q13;q21)]  
Fusion: TCGANCAM2 21q21.1 CRYL1 13q12.11 PRAD
Fusion: TCGAPDE7A 8q13.1 NCAM2 21q21.1 LUAD
Fusion: TCGATEC - NCAM2 21q21.1 LUAD
Fusion: TCGAZNF146 19q13.12 NCAM2 21q21.1 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNCAM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NCAM2
dbVarNCAM2
ClinVarNCAM2
1000_GenomesNCAM2 
Exome Variant ServerNCAM2
ExAC (Exome Aggregation Consortium)NCAM2 (select the gene name)
Genetic variants : HAPMAP4685
Genomic Variants (DGV)NCAM2 [DGVbeta]
DECIPHER (Syndromes)21:22370633-22912517  ENSG00000154654
CONAN: Copy Number AnalysisNCAM2 
Mutations
ICGC Data PortalNCAM2 
TCGA Data PortalNCAM2 
Broad Tumor PortalNCAM2
OASIS PortalNCAM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNCAM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNCAM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NCAM2
DgiDB (Drug Gene Interaction Database)NCAM2
DoCM (Curated mutations)NCAM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NCAM2 (select a term)
intoGenNCAM2
Cancer3DNCAM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602040   
Orphanet
MedgenNCAM2
Genetic Testing Registry NCAM2
NextProtO15394 [Medical]
TSGene4685
GENETestsNCAM2
Huge Navigator NCAM2 [HugePedia]
snp3D : Map Gene to Disease4685
BioCentury BCIQNCAM2
ClinGenNCAM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4685
Chemical/Pharm GKB GenePA31460
Clinical trialNCAM2
Miscellaneous
canSAR (ICR)NCAM2 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNCAM2
EVEXNCAM2
GoPubMedNCAM2
iHOPNCAM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:18:18 CET 2017

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