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NFIB (nuclear factor I/B)

Identity

Other namesCTF
HMGIC/NFIB
NF-I/B
NF1-B
NFI-B
NFI-RED
NFIB2
NFIB3
HGNC (Hugo) NFIB
LocusID (NCBI) 4781
Location 9p23
Location_base_pair Starts at 14081842 and ends at 14314045 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas)

Solid Tumors AmeloblastomID5945 MedulloblastomaID5065 rhab5004 rhabID5004 blad5001

External links

Nomenclature
HGNC (Hugo)NFIB   7785
Cards
Entrez_Gene (NCBI)NFIB  4781  nuclear factor I/B
GeneCards (Weizmann)NFIB
Ensembl (Hinxton)ENSG00000147862 [Gene_View]  chr9:14081842-14314045 [Contig_View]  NFIB [Vega]
ICGC DataPortalENSG00000147862
AceView (NCBI)NFIB
Genatlas (Paris)NFIB
WikiGenes4781
SOURCE (Princeton)NM_001190737 NM_001190738 NM_001282787 NM_005596
Genomic and cartography
GoldenPath (UCSC)NFIB  -  9p23   chr9:14081842-14314045 -  9p23   [Description]    (hg19-Feb_2009)
EnsemblNFIB - 9p23 [CytoView]
Mapping of homologs : NCBINFIB [Mapview]
OMIM600728   
Gene and transcription
Genbank (Entrez)AF022215 AI140312 AK094066 AK129782 AK131233
RefSeq transcript (Entrez)NM_001190737 NM_001190738 NM_001282787 NM_005596
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NT_008413 NW_001839149 NW_004929342
Consensus coding sequences : CCDS (NCBI)NFIB
Cluster EST : UnigeneHs.644095 [ NCBI ]
CGAP (NCI)Hs.644095
Alternative Splicing : Fast-db (Paris)GSHG0030671
Alternative Splicing GalleryENSG00000147862
Gene ExpressionNFIB [ NCBI-GEO ]     NFIB [ SEEK ]   NFIB [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00712 (Uniprot)
NextProtO00712  [Medical]
With graphics : InterProO00712
Splice isoforms : SwissVarO00712 (Swissvar)
Domaine pattern : Prosite (Expaxy)CTF_NFI_1 (PS00349)    CTF_NFI_2 (PS51080)   
Domains : Interpro (EBI)CTF/NFI    CTF/NFI_DNA-bd-dom    CTF/NFI_DNA-bd_CS    CTF/NFI_DNA-bd_N    MAD_homology1_Dwarfin-type   
Related proteins : CluSTrO00712
Domain families : Pfam (Sanger)CTF_NFI (PF00859)    MH1 (PF03165)    NfI_DNAbd_pre-N (PF10524)   
Domain families : Pfam (NCBI)pfam00859    pfam03165    pfam10524   
Domain families : Smart (EMBL)DWA (SM00523)  
DMDM Disease mutations4781
Blocks (Seattle)O00712
Human Protein AtlasENSG00000147862
Peptide AtlasO00712
HPRD09008
IPIIPI00953386   IPI00983554   IPI00984295   IPI00472959   IPI00470473   IPI00646731   IPI00646279   IPI00473116   IPI00642237   
Protein Interaction databases
DIP (DOE-UCLA)O00712
IntAct (EBI)O00712
FunCoupENSG00000147862
BioGRIDNFIB
IntegromeDBNFIB
STRING (EMBL)NFIB
Ontologies - Pathways
QuickGOO00712
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  sequence-specific DNA binding RNA polymerase II transcription factor activity  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription  RNA polymerase II transcription corepressor activity  chondrocyte differentiation  DNA binding  DNA binding  double-stranded DNA binding  nucleus  nucleolus  DNA replication  transcription from RNA polymerase II promoter  glial cell differentiation  principal sensory nucleus of trigeminal nerve development  anterior commissure morphogenesis  hindbrain development  negative regulation of DNA binding  cerebellar mossy fiber  positive regulation of transcription from RNA polymerase II promoter  Clara cell differentiation  Type I pneumocyte differentiation  Type II pneumocyte differentiation  lung ciliated cell differentiation  commissural neuron axon guidance  negative regulation of mesenchymal cell proliferation involved in lung development  negative regulation of epithelial cell proliferation involved in lung morphogenesis  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  sequence-specific DNA binding RNA polymerase II transcription factor activity  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription  RNA polymerase II transcription corepressor activity  chondrocyte differentiation  DNA binding  DNA binding  double-stranded DNA binding  nucleus  nucleolus  DNA replication  transcription from RNA polymerase II promoter  glial cell differentiation  principal sensory nucleus of trigeminal nerve development  anterior commissure morphogenesis  hindbrain development  negative regulation of DNA binding  cerebellar mossy fiber  positive regulation of transcription from RNA polymerase II promoter  Clara cell differentiation  Type I pneumocyte differentiation  Type II pneumocyte differentiation  lung ciliated cell differentiation  commissural neuron axon guidance  negative regulation of mesenchymal cell proliferation involved in lung development  negative regulation of epithelial cell proliferation involved in lung morphogenesis  
Protein Interaction DatabaseNFIB
Wikipedia pathwaysNFIB
Gene fusion - rearrangments
Rearrangement : COSMICNFIB [9p23]  -  MYB [6q23.3]
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)NFIB
SNP (GeneSNP Utah)NFIB
SNP : HGBaseNFIB
Genetic variants : HAPMAPNFIB
1000_GenomesNFIB 
ICGC programENSG00000147862 
Cancer Gene: CensusNFIB 
CONAN: Copy Number AnalysisNFIB 
Somatic Mutations in Cancer : COSMICNFIB 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)9:14081842-14314045
Mutations and Diseases : HGMDNFIB
OMIM600728   
MedgenNFIB
GENETestsNFIB
Disease Genetic AssociationNFIB
Huge Navigator NFIB [HugePedia]  NFIB [HugeCancerGEM]
Genomic VariantsNFIB  NFIB [DGVbeta]
Exome VariantNFIB
dbVarNFIB
ClinVarNFIB
snp3D : Map Gene to Disease4781
General knowledge
Homologs : HomoloGeneNFIB
Homology/Alignments : Family Browser (UCSC)NFIB
Phylogenetic Trees/Animal Genes : TreeFamNFIB
Chemical/Protein Interactions : CTD4781
Chemical/Pharm GKB GenePA31591
Clinical trialNFIB
Cancer Resource (Charite)ENSG00000147862
Other databases
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
CoreMineNFIB
GoPubMedNFIB
iHOPNFIB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:44:57 CET 2014

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