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NFIB (nuclear factor I B)

Identity

Alias (NCBI)CTF
HMGIC/NFIB
MACID
NF-I/B
NF1-B
NFI-B
NFI-RED
NFIB2
NFIB3
HGNC (Hugo) NFIB
HGNC Alias symbNFI-RED
NFIB2
NFIB3
HGNC Previous namenuclear factor I/B
LocusID (NCBI) 4781
Atlas_Id 253
Location 9p23  [Link to chromosome band 9p23]
Location_base_pair Starts at 14081843 and ends at 14314046 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HMGA2 (12q14.3) / NFIB (9p23)MPDZ (9p23) / NFIB (9p23)MYB (6q23.3) / NFIB (9p23)
NFIB (9p23) / AIG1 (6q24.2)NFIB (9p23) / ERBB4 (2q34)NFIB (9p23) / FREM1 (9p22.3)
NFIB (9p23) / HEATR5B (2p22.2)NFIB (9p23) / HMGA2 (12q14.3)NFIB (9p23) / KIF13B (8p12)
NFIB (9p23) / MAN1A1 (6q22.31)NFIB (9p23) / MYB (6q23.3)NFIB (9p23) / NFIB (9p23)
NFIB (9p23) / SREK1 (5q12.3)NFIB (9p23) / STRN (2p22.2)NFIB (9p23) / ZDHHC21 (9p22.3)
NFIB 9p23 / MYB 6q23.3MPDZ 9p23 / NFIB 9p23MYB 6q23.3 / NFIB 9p23
NFIB 9p23 / FREM1 9p22.3NFIB 9p23 / HEATR5B 2p22.2NFIB 9p23 / STRN 2p22.2
NFIB 9p23 / ZDHHC21 9p22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NFIB   7785
Cards
Entrez_Gene (NCBI)NFIB    nuclear factor I B
AliasesCTF; HMGIC/NFIB; MACID; NF-I/B; 
NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3
GeneCards (Weizmann)NFIB
Ensembl hg19 (Hinxton)ENSG00000147862 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147862 [Gene_View]  ENSG00000147862 [Sequence]  chr9:14081843-14314046 [Contig_View]  NFIB [Vega]
ICGC DataPortalENSG00000147862
TCGA cBioPortalNFIB
AceView (NCBI)NFIB
Genatlas (Paris)NFIB
SOURCE (Princeton)NFIB
Genetics Home Reference (NIH)NFIB
Genomic and cartography
GoldenPath hg38 (UCSC)NFIB  -     chr9:14081843-14314046 -  9p23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NFIB  -     9p23   [Description]    (hg19-Feb_2009)
GoldenPathNFIB - 9p23 [CytoView hg19]  NFIB - 9p23 [CytoView hg38]
ImmunoBaseENSG00000147862
Genome Data Viewer NCBINFIB [Mapview hg19]  
OMIM600728   618286   
Gene and transcription
Genbank (Entrez)AF022215 AI140312 AK094066 AK129782 AK131233
RefSeq transcript (Entrez)NM_001190737 NM_001190738 NM_001282787 NM_001369458 NM_001369459 NM_001369460 NM_001369461 NM_001369462 NM_001369463 NM_001369464 NM_001369465 NM_001369466 NM_001369467 NM_001369468 NM_001369469 NM_001369470 NM_001369471 NM_001369472 NM_001369473 NM_001369474 NM_001369475 NM_001369476 NM_001369477 NM_001369478 NM_001369479 NM_001369480 NM_001369481 NM_005596
Consensus coding sequences : CCDS (NCBI)NFIB
Gene ExpressionNFIB [ NCBI-GEO ]   NFIB [ EBI - ARRAY_EXPRESS ]   NFIB [ SEEK ]   NFIB [ MEM ]
Gene Expression Viewer (FireBrowse)NFIB [ Firebrowse - Broad ]
GenevisibleExpression of NFIB in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4781
GTEX Portal (Tissue expression)NFIB
Human Protein AtlasENSG00000147862-NFIB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00712   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00712  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00712
PhosPhoSitePlusO00712
Domaine pattern : Prosite (Expaxy)CTF_NFI_1 (PS00349)    CTF_NFI_2 (PS51080)   
Domains : Interpro (EBI)CTF/NFI    CTF/NFI_DNA-bd-dom    CTF/NFI_DNA-bd_CS    CTF/NFI_DNA-bd_N    MAD_homology1_Dwarfin-type   
Domain families : Pfam (Sanger)CTF_NFI (PF00859)    MH1 (PF03165)    NfI_DNAbd_pre-N (PF10524)   
Domain families : Pfam (NCBI)pfam00859    pfam03165    pfam10524   
Domain families : Smart (EMBL)DWA (SM00523)  
Conserved Domain (NCBI)NFIB
SuperfamilyO00712
AlphaFold pdb e-kbO00712   
Human Protein Atlas [tissue]ENSG00000147862-NFIB [tissue]
HPRD09008
Protein Interaction databases
DIP (DOE-UCLA)O00712
IntAct (EBI)O00712
BioGRIDNFIB
STRING (EMBL)NFIB
ZODIACNFIB
Ontologies - Pathways
QuickGOO00712
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  fibrillar center  chondrocyte differentiation  DNA binding  nucleus  nucleus  nucleoplasm  DNA replication  regulation of transcription by RNA polymerase II  brain development  response to bacterium  glial cell differentiation  principal sensory nucleus of trigeminal nerve development  anterior commissure morphogenesis  hindbrain development  cerebellar mossy fiber  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  club cell differentiation  type I pneumocyte differentiation  type II pneumocyte differentiation  salivary gland cavitation  cell differentiation involved in salivary gland development  lung ciliated cell differentiation  commissural neuron axon guidance  negative regulation of pri-miRNA transcription by RNA polymerase II  sequence-specific double-stranded DNA binding  negative regulation of mesenchymal cell proliferation involved in lung development  negative regulation of epithelial cell proliferation involved in lung morphogenesis  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  fibrillar center  chondrocyte differentiation  DNA binding  nucleus  nucleus  nucleoplasm  DNA replication  regulation of transcription by RNA polymerase II  brain development  response to bacterium  glial cell differentiation  principal sensory nucleus of trigeminal nerve development  anterior commissure morphogenesis  hindbrain development  cerebellar mossy fiber  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  club cell differentiation  type I pneumocyte differentiation  type II pneumocyte differentiation  salivary gland cavitation  cell differentiation involved in salivary gland development  lung ciliated cell differentiation  commissural neuron axon guidance  negative regulation of pri-miRNA transcription by RNA polymerase II  sequence-specific double-stranded DNA binding  negative regulation of mesenchymal cell proliferation involved in lung development  negative regulation of epithelial cell proliferation involved in lung morphogenesis  
NDEx NetworkNFIB
Atlas of Cancer Signalling NetworkNFIB
Wikipedia pathwaysNFIB
Orthology - Evolution
OrthoDB4781
GeneTree (enSembl)ENSG00000147862
Phylogenetic Trees/Animal Genes : TreeFamNFIB
Homologs : HomoloGeneNFIB
Homology/Alignments : Family Browser (UCSC)NFIB
Gene fusions - Rearrangements
Fusion : MitelmanHMGA2/NFIB [12q14.3/9p23]  
Fusion : MitelmanMYB/NFIB [6q23.3/9p23]  
Fusion : MitelmanNFIB/AIG1 [9p23/6q24.2]  
Fusion : MitelmanNFIB/FREM1 [9p23/9p22.3]  
Fusion : MitelmanNFIB/HEATR5B [9p23/2p22.2]  
Fusion : MitelmanNFIB/MAN1A1 [9p23/6q22.31]  
Fusion : MitelmanNFIB/STRN [9p23/2p22.2]  
Fusion : MitelmanNFIB/ZDHHC21 [9p23/9p22.3]  
Fusion : QuiverNFIB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFIB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFIB
dbVarNFIB
ClinVarNFIB
MonarchNFIB
1000_GenomesNFIB 
Exome Variant ServerNFIB
GNOMAD BrowserENSG00000147862
Varsome BrowserNFIB
ACMGNFIB variants
VarityO00712
Genomic Variants (DGV)NFIB [DGVbeta]
DECIPHERNFIB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNFIB 
Mutations
ICGC Data PortalNFIB 
TCGA Data PortalNFIB 
Broad Tumor PortalNFIB
OASIS PortalNFIB [ Somatic mutations - Copy number]
Cancer Gene: CensusNFIB 
Somatic Mutations in Cancer : COSMICNFIB  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNFIB
Mutations and Diseases : HGMDNFIB
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNFIB
DgiDB (Drug Gene Interaction Database)NFIB
DoCM (Curated mutations)NFIB
CIViC (Clinical Interpretations of Variants in Cancer)NFIB
Cancer3DNFIB
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600728    618286   
Orphanet
DisGeNETNFIB
MedgenNFIB
Genetic Testing Registry NFIB
NextProtO00712 [Medical]
GENETestsNFIB
Target ValidationNFIB
Huge Navigator NFIB [HugePedia]
ClinGenNFIB
Clinical trials, drugs, therapy
MyCancerGenomeNFIB
Protein Interactions : CTDNFIB
Pharm GKB GenePA31591
PharosO00712
Clinical trialNFIB
Miscellaneous
canSAR (ICR)NFIB
HarmonizomeNFIB
DataMed IndexNFIB
Probes
Litterature
PubMed87 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNFIB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:22:39 CEST 2021

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