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NKD2 (naked cuticle homolog 2)

Identity

Alias_namesnaked cuticle homolog 2 (Drosophila)
Alias_symbol (synonym)Naked2
Other alias
HGNC (Hugo) NKD2
LocusID (NCBI) 85409
Atlas_Id 45982
Location 5p15.33  [Link to chromosome band 5p15]
Location_base_pair Starts at 1008962 and ends at 1038812 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EHBP1 (2p15) / NKD2 (5p15.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NKD2   17046
Cards
Entrez_Gene (NCBI)NKD2  85409  naked cuticle homolog 2
AliasesNaked2
GeneCards (Weizmann)NKD2
Ensembl hg19 (Hinxton)ENSG00000145506 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145506 [Gene_View]  chr5:1008962-1038812 [Contig_View]  NKD2 [Vega]
ICGC DataPortalENSG00000145506
TCGA cBioPortalNKD2
AceView (NCBI)NKD2
Genatlas (Paris)NKD2
WikiGenes85409
SOURCE (Princeton)NKD2
Genetics Home Reference (NIH)NKD2
Genomic and cartography
GoldenPath hg38 (UCSC)NKD2  -     chr5:1008962-1038812 +  5p15.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NKD2  -     5p15.33   [Description]    (hg19-Feb_2009)
EnsemblNKD2 - 5p15.33 [CytoView hg19]  NKD2 - 5p15.33 [CytoView hg38]
Mapping of homologs : NCBINKD2 [Mapview hg19]  NKD2 [Mapview hg38]
OMIM607852   
Gene and transcription
Genbank (Entrez)AB062887 AF358137 BC004940 BC012176 BE061409
RefSeq transcript (Entrez)NM_001271082 NM_033120
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_187548
Consensus coding sequences : CCDS (NCBI)NKD2
Cluster EST : UnigeneHs.240951 [ NCBI ]
CGAP (NCI)Hs.240951
Alternative Splicing GalleryENSG00000145506
Gene ExpressionNKD2 [ NCBI-GEO ]   NKD2 [ EBI - ARRAY_EXPRESS ]   NKD2 [ SEEK ]   NKD2 [ MEM ]
Gene Expression Viewer (FireBrowse)NKD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85409
GTEX Portal (Tissue expression)NKD2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969F2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969F2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969F2
Splice isoforms : SwissVarQ969F2
PhosPhoSitePlusQ969F2
Domaine pattern : Prosite (Expaxy)EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_hand_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NKD2
DMDM Disease mutations85409
Blocks (Seattle)NKD2
SuperfamilyQ969F2
Human Protein AtlasENSG00000145506
Peptide AtlasQ969F2
HPRD08483
IPIIPI00056319   IPI00061527   IPI00442988   
Protein Interaction databases
DIP (DOE-UCLA)Q969F2
IntAct (EBI)Q969F2
FunCoupENSG00000145506
BioGRIDNKD2
STRING (EMBL)NKD2
ZODIACNKD2
Ontologies - Pathways
QuickGOQ969F2
Ontology : AmiGOcalcium ion binding  protein binding  plasma membrane  exocytosis  positive regulation of protein processing  Wnt signaling pathway  basolateral plasma membrane  lateral plasma membrane  growth factor binding  cytoplasmic vesicle  ubiquitin protein ligase binding  myosin heavy chain binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  Golgi vesicle fusion to target membrane  ATPase binding  exocytic vesicle  cell periphery  protein targeting to plasma membrane  positive regulation of establishment of protein localization to plasma membrane  negative regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIcalcium ion binding  protein binding  plasma membrane  exocytosis  positive regulation of protein processing  Wnt signaling pathway  basolateral plasma membrane  lateral plasma membrane  growth factor binding  cytoplasmic vesicle  ubiquitin protein ligase binding  myosin heavy chain binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  Golgi vesicle fusion to target membrane  ATPase binding  exocytic vesicle  cell periphery  protein targeting to plasma membrane  positive regulation of establishment of protein localization to plasma membrane  negative regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  
Pathways : KEGGWnt signaling pathway   
NDEx NetworkNKD2
Atlas of Cancer Signalling NetworkNKD2
Wikipedia pathwaysNKD2
Orthology - Evolution
OrthoDB85409
GeneTree (enSembl)ENSG00000145506
Phylogenetic Trees/Animal Genes : TreeFamNKD2
HOVERGENQ969F2
HOGENOMQ969F2
Homologs : HomoloGeneNKD2
Homology/Alignments : Family Browser (UCSC)NKD2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNKD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NKD2
dbVarNKD2
ClinVarNKD2
1000_GenomesNKD2 
Exome Variant ServerNKD2
ExAC (Exome Aggregation Consortium)NKD2 (select the gene name)
Genetic variants : HAPMAP85409
Genomic Variants (DGV)NKD2 [DGVbeta]
DECIPHERNKD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNKD2 
Mutations
ICGC Data PortalNKD2 
TCGA Data PortalNKD2 
Broad Tumor PortalNKD2
OASIS PortalNKD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNKD2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNKD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NKD2
DgiDB (Drug Gene Interaction Database)NKD2
DoCM (Curated mutations)NKD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NKD2 (select a term)
intoGenNKD2
Cancer3DNKD2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607852   
Orphanet
MedgenNKD2
Genetic Testing Registry NKD2
NextProtQ969F2 [Medical]
TSGene85409
GENETestsNKD2
Huge Navigator NKD2 [HugePedia]
snp3D : Map Gene to Disease85409
BioCentury BCIQNKD2
ClinGenNKD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85409
Chemical/Pharm GKB GenePA31638
Clinical trialNKD2
Miscellaneous
canSAR (ICR)NKD2 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNKD2
EVEXNKD2
GoPubMedNKD2
iHOPNKD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:28:43 CEST 2017

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