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PABPN1 (poly(A) binding protein, nuclear 1)

Identity

Other namesOPMD
PAB2
PABII
PABP-2
PABP2
HGNC (Hugo) PABPN1
LocusID (NCBI) 8106
Location 14q11.2
Location_base_pair Starts at 23789397 and ends at 23795394 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PABPN1   8565
Cards
Entrez_Gene (NCBI)PABPN1  8106  poly(A) binding protein, nuclear 1
GeneCards (Weizmann)PABPN1
Ensembl (Hinxton) [Gene_View]  chr14:23789397-23795394 [Contig_View]  PABPN1 [Vega]
AceView (NCBI)PABPN1
Genatlas (Paris)PABPN1
WikiGenes8106
SOURCE (Princeton)NM_004643
Genomic and cartography
GoldenPath (UCSC)PABPN1  -  14q11.2   chr14:23789397-23795394 +  14q11.2   [Description]    (hg19-Feb_2009)
EnsemblPABPN1 - 14q11.2 [CytoView]
Mapping of homologs : NCBIPABPN1 [Mapview]
OMIM164300   602279   
Gene and transcription
Genbank (Entrez)AK293633 BC010939 BI830835 BM979311 BX247976
RefSeq transcript (Entrez)NM_004643
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NG_008239 NT_026437 NW_001838110 NW_004929393
Consensus coding sequences : CCDS (NCBI)PABPN1
Cluster EST : UnigeneHs.707712 [ NCBI ]
CGAP (NCI)Hs.707712
Alternative Splicing : Fast-db (Paris)GSHG0008726
Gene ExpressionPABPN1 [ NCBI-GEO ]     PABPN1 [ SEEK ]   PABPN1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86U42 (Uniprot)
NextProtQ86U42  [Medical]
With graphics : InterProQ86U42
Splice isoforms : SwissVarQ86U42 (Swissvar)
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom   
Related proteins : CluSTrQ86U42
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
DMDM Disease mutations8106
Blocks (Seattle)Q86U42
PDB (SRS)3B4D    3B4M    3UCG   
PDB (PDBSum)3B4D    3B4M    3UCG   
PDB (IMB)3B4D    3B4M    3UCG   
PDB (RSDB)3B4D    3B4M    3UCG   
Peptide AtlasQ86U42
HPRD03787
IPIIPI00005792   IPI00414963   IPI00030249   IPI01025694   IPI01025700   
Protein Interaction databases
DIP (DOE-UCLA)Q86U42
IntAct (EBI)Q86U42
BioGRIDPABPN1
InParanoidQ86U42
Interologous Interaction database Q86U42
IntegromeDBPABPN1
STRING (EMBL)PABPN1
Ontologies - Pathways
Ontology : AmiGOnucleotide binding  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  transcription from RNA polymerase II promoter  termination of RNA polymerase II transcription  RNA processing  muscle contraction  RNA splicing  gene expression  poly(A)+ mRNA export from nucleus  modulation by virus of host morphology or physiology  modulation by virus of host process  viral life cycle  ribonucleoprotein complex  mRNA 3'-end processing  poly(A) RNA binding  modification by virus of host mRNA processing  
Ontology : EGO-EBInucleotide binding  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  transcription from RNA polymerase II promoter  termination of RNA polymerase II transcription  RNA processing  muscle contraction  RNA splicing  gene expression  poly(A)+ mRNA export from nucleus  modulation by virus of host morphology or physiology  modulation by virus of host process  viral life cycle  ribonucleoprotein complex  mRNA 3'-end processing  poly(A) RNA binding  modification by virus of host mRNA processing  
Pathways : BIOCARTAPolyadenylation of mRNA [Genes]   
Pathways : KEGGmRNA surveillance pathway    Influenza A   
Protein Interaction DatabasePABPN1
Wikipedia pathwaysPABPN1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PABPN1
SNP (GeneSNP Utah)PABPN1
SNP : HGBasePABPN1
Genetic variants : HAPMAPPABPN1
1000_GenomesPABPN1 
CONAN: Copy Number AnalysisPABPN1 
Somatic Mutations in Cancer : COSMICPABPN1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)Leiden Muscular Dystrophy pages
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDPABPN1
OMIM164300    602279   
MedgenPABPN1
GENETestsPABPN1
Disease Genetic AssociationPABPN1
Huge Navigator PABPN1 [HugePedia]  PABPN1 [HugeCancerGEM]
Genomic VariantsPABPN1  PABPN1 [DGVbeta]
Exome VariantPABPN1
dbVarPABPN1
ClinVarPABPN1
snp3D : Map Gene to Disease8106
General knowledge
Homologs : HomoloGenePABPN1
Homology/Alignments : Family Browser (UCSC)PABPN1
Phylogenetic Trees/Animal Genes : TreeFamPABPN1
Chemical/Protein Interactions : CTD8106
Chemical/Pharm GKB GenePA32891
Clinical trialPABPN1
Other databases
Probes
Litterature
PubMed77 Pubmed reference(s) in Entrez
CoreMinePABPN1
iHOPPABPN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 13:06:28 CEST 2014

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