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PANX2 (pannexin 2)

Identity

Alias_symbol (synonym)hPANX2
PX2
Other alias
HGNC (Hugo) PANX2
LocusID (NCBI) 56666
Atlas_Id 50085
Location 22q13.33  [Link to chromosome band 22q13]
Location_base_pair Starts at 50170731 and ends at 50180295 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
UNKL (16p13.3) / PANX2 (22q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PANX2   8600
Cards
Entrez_Gene (NCBI)PANX2  56666  pannexin 2
AliasesPX2; hPANX2
GeneCards (Weizmann)PANX2
Ensembl hg19 (Hinxton)ENSG00000073150 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000073150 [Gene_View]  chr22:50170731-50180295 [Contig_View]  PANX2 [Vega]
ICGC DataPortalENSG00000073150
TCGA cBioPortalPANX2
AceView (NCBI)PANX2
Genatlas (Paris)PANX2
WikiGenes56666
SOURCE (Princeton)PANX2
Genetics Home Reference (NIH)PANX2
Genomic and cartography
GoldenPath hg38 (UCSC)PANX2  -     chr22:50170731-50180295 +  22q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PANX2  -     22q13.33   [Description]    (hg19-Feb_2009)
EnsemblPANX2 - 22q13.33 [CytoView hg19]  PANX2 - 22q13.33 [CytoView hg38]
Mapping of homologs : NCBIPANX2 [Mapview hg19]  PANX2 [Mapview hg38]
OMIM608421   
Gene and transcription
Genbank (Entrez)AF398510 AF398511 AK096019 AK123508 AK299910
RefSeq transcript (Entrez)NM_001160300 NM_052839
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PANX2
Cluster EST : UnigeneHs.440092 [ NCBI ]
CGAP (NCI)Hs.440092
Alternative Splicing GalleryENSG00000073150
Gene ExpressionPANX2 [ NCBI-GEO ]   PANX2 [ EBI - ARRAY_EXPRESS ]   PANX2 [ SEEK ]   PANX2 [ MEM ]
Gene Expression Viewer (FireBrowse)PANX2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56666
GTEX Portal (Tissue expression)PANX2
Human Protein AtlasENSG00000073150-PANX2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96RD6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96RD6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96RD6
Splice isoforms : SwissVarQ96RD6
PhosPhoSitePlusQ96RD6
Domaine pattern : Prosite (Expaxy)PANNEXIN (PS51013)   
Domains : Interpro (EBI)Innexin   
Domain families : Pfam (Sanger)Innexin (PF00876)   
Domain families : Pfam (NCBI)pfam00876   
Conserved Domain (NCBI)PANX2
DMDM Disease mutations56666
Blocks (Seattle)PANX2
SuperfamilyQ96RD6
Human Protein Atlas [tissue]ENSG00000073150-PANX2 [tissue]
Peptide AtlasQ96RD6
HPRD09760
IPIIPI00066288   IPI00472910   IPI00964395   IPI00645328   IPI00852585   
Protein Interaction databases
DIP (DOE-UCLA)Q96RD6
IntAct (EBI)Q96RD6
FunCoupENSG00000073150
BioGRIDPANX2
STRING (EMBL)PANX2
ZODIACPANX2
Ontologies - Pathways
QuickGOQ96RD6
Ontology : AmiGOresponse to ischemia  cytoplasm  plasma membrane  plasma membrane  gap junction  cation transport  cell-cell signaling  endomembrane system  integral component of membrane  wide pore channel activity  protein hexamerization  gap junction hemi-channel activity  transmembrane transport  
Ontology : EGO-EBIresponse to ischemia  cytoplasm  plasma membrane  plasma membrane  gap junction  cation transport  cell-cell signaling  endomembrane system  integral component of membrane  wide pore channel activity  protein hexamerization  gap junction hemi-channel activity  transmembrane transport  
NDEx NetworkPANX2
Atlas of Cancer Signalling NetworkPANX2
Wikipedia pathwaysPANX2
Orthology - Evolution
OrthoDB56666
GeneTree (enSembl)ENSG00000073150
Phylogenetic Trees/Animal Genes : TreeFamPANX2
HOVERGENQ96RD6
HOGENOMQ96RD6
Homologs : HomoloGenePANX2
Homology/Alignments : Family Browser (UCSC)PANX2
Gene fusions - Rearrangements
Tumor Fusion PortalPANX2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPANX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PANX2
dbVarPANX2
ClinVarPANX2
1000_GenomesPANX2 
Exome Variant ServerPANX2
ExAC (Exome Aggregation Consortium)ENSG00000073150
GNOMAD BrowserENSG00000073150
Genetic variants : HAPMAP56666
Genomic Variants (DGV)PANX2 [DGVbeta]
DECIPHERPANX2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPANX2 
Mutations
ICGC Data PortalPANX2 
TCGA Data PortalPANX2 
Broad Tumor PortalPANX2
OASIS PortalPANX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPANX2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPANX2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PANX2
DgiDB (Drug Gene Interaction Database)PANX2
DoCM (Curated mutations)PANX2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PANX2 (select a term)
intoGenPANX2
Cancer3DPANX2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608421   
Orphanet
DisGeNETPANX2
MedgenPANX2
Genetic Testing Registry PANX2
NextProtQ96RD6 [Medical]
TSGene56666
GENETestsPANX2
Target ValidationPANX2
Huge Navigator PANX2 [HugePedia]
snp3D : Map Gene to Disease56666
BioCentury BCIQPANX2
ClinGenPANX2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56666
Chemical/Pharm GKB GenePA32930
Clinical trialPANX2
Miscellaneous
canSAR (ICR)PANX2 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePANX2
EVEXPANX2
GoPubMedPANX2
iHOPPANX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:27:43 CET 2017

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