PECAM1 (platelet/endothelial cell adhesion molecule 1)

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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

PECAM1 (platelet/endothelial cell adhesion molecule 1)

Identity

Other names	CD31
	CD31/EndoCAM
	GPIIA'
	PECA1
	PECAM-1
	endoCAM
HGNC (Hugo)	PECAM1
LocusID (NCBI)	5175
Location	17q23.3
Location_base_pair	Starts at 62396777 and ends at 62407083 bp from pter ( according to hg19-Feb_2009)
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to How to contribute

DNA/RNA

External links

	Nomenclature
HGNC (Hugo)	PECAM1 8823
	Cards
Entrez_Gene (NCBI)	PECAM1 5175 platelet/endothelial cell adhesion molecule 1
GeneCards (Weizmann)	PECAM1
Ensembl hg19 (Hinxton)	[Gene_View] chr17:62396777-62407083 [Contig_View] PECAM1 [Vega]
Ensembl hg38 (Hinxton)	[Gene_View] chr17:62396777-62407083 [Contig_View] PECAM1 [Vega]
cBioPortal	PECAM1
AceView (NCBI)	PECAM1
Genatlas (Paris)	PECAM1
WikiGenes	5175
SOURCE (Princeton)	PECAM1
	Genomic and cartography
GoldenPath hg19 (UCSC)	PECAM1 - chr17:62396777-62407083 - 17q23.3 [Description] (hg19-Feb_2009)
GoldenPath hg38 (UCSC)	PECAM1 - 17q23.3 [Description] (hg38-Dec_2013)
Ensembl	PECAM1 - 17q23.3 [CytoView hg19] PECAM1 - 17q23.3 [CytoView hg38]
Mapping of homologs : NCBI	PECAM1 [Mapview hg19] PECAM1 [Mapview hg38]
OMIM	173445
	Gene and transcription
Genbank (Entrez)	AF281287 AF281288 AF281289 AF281290 AF281291
RefSeq transcript (Entrez)	NM_000442
RefSeq genomic (Entrez)	AC_000149 NC_000017 NC_018928 NT_010783 NW_001838450 NW_004929407
Consensus coding sequences : CCDS (NCBI)	PECAM1
Cluster EST : Unigene	Hs.514412 [ NCBI ]
CGAP (NCI)	Hs.514412
Alternative Splicing : Fast-db (Paris)	GSHG0039312
Gene Expression	PECAM1 [ NCBI-GEO ] PECAM1 [ SEEK ] PECAM1 [ MEM ]
SOURCE (Princeton)	Expression in : [Normal Tissue Atlas] [carcinoma Classsification] [NCI60]
	Protein : pattern, domain, 3D structure
UniProt/SwissProt	P16284 (Uniprot)
NextProt	P16284 [Medical]
With graphics : InterPro	P16284
Splice isoforms : SwissVar	P16284 (Swissvar)
Domaine pattern : Prosite (Expaxy)	IG_LIKE (PS50835)
Domains : Interpro (EBI)	Ig-like_dom Ig-like_fold Ig_sub
Related proteins : CluSTr	P16284
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)	IG (SM00409)
DMDM Disease mutations	5175
Blocks (Seattle)	P16284
PDB (SRS)	2KY5
PDB (PDBSum)	2KY5
PDB (IMB)	2KY5
PDB (RSDB)	2KY5
Peptide Atlas	P16284
HPRD	01425
IPI	IPI00295618 IPI00470719 IPI00470720 IPI00914041 IPI01010172 IPI00871352
	Protein Interaction databases
DIP (DOE-UCLA)	P16284
IntAct (EBI)	P16284
BioGRID	PECAM1
IntegromeDB	PECAM1
STRING (EMBL)	PECAM1
	Ontologies - Pathways
QuickGO	P16284
Ontology : AmiGO	platelet degranulation protein binding extracellular space plasma membrane plasma membrane phagocytosis cell adhesion signal transduction blood coagulation cell recognition integral component of membrane cell junction platelet activation extracellular matrix organization platelet alpha granule membrane leukocyte migration diapedesis extracellular vesicular exosome glomerular endothelium development
Ontology : EGO-EBI	platelet degranulation protein binding extracellular space plasma membrane plasma membrane phagocytosis cell adhesion signal transduction blood coagulation cell recognition integral component of membrane cell junction platelet activation extracellular matrix organization platelet alpha granule membrane leukocyte migration diapedesis extracellular vesicular exosome glomerular endothelium development
Pathways : BIOCARTA	Neutrophil and Its Surface Molecules [Genes] Adhesion and Diapedesis of Granulocytes [Genes] Adhesion Molecules on Lymphocyte [Genes] Monocyte and its Surface Molecules [Genes] Adhesion and Diapedesis of Lymphocytes [Genes] Cell to Cell Adhesion Signaling [Genes]
Pathways : KEGG	Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Malaria
Protein Interaction Database	PECAM1
DoCM (Curated mutations)	PECAM1
Wikipedia pathways	PECAM1
	Gene fusion - rearrangements
	Polymorphisms : SNP, variants
NCBI Variation Viewer	PECAM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)	PECAM1
dbVar	PECAM1
ClinVar	PECAM1
1000_Genomes	PECAM1
Exome Variant Server	PECAM1
SNP (GeneSNP Utah)	PECAM1
SNP : HGBase	PECAM1
Genetic variants : HAPMAP	PECAM1
Genomic Variants (DGV)	PECAM1 [DGVbeta]
	Mutations
LOVD (Leiden Open Variation Database)	Whole genome datasets
LOVD (Leiden Open Variation Database)	LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)	LOVD 3.0 shared installation
Impact of mutations	[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor]
	Diseases
DECIPHER (Syndromes)	17:62396777-62407083
Mutations and Diseases : HGMD	PECAM1
OMIM	173445
Medgen	PECAM1
NextProt	P16284 [Medical]
GENETests	PECAM1
Disease Genetic Association	PECAM1
Huge Navigator	PECAM1 [HugePedia] PECAM1 [HugeCancerGEM]
snp3D : Map Gene to Disease	5175
DGIdb (Drug Gene Interaction db)	PECAM1
	General knowledge
Homologs : HomoloGene	PECAM1
Homology/Alignments : Family Browser (UCSC)	PECAM1
Phylogenetic Trees/Animal Genes : TreeFam	PECAM1
Chemical/Protein Interactions : CTD	5175
Chemical/Pharm GKB Gene	PA33167
Clinical trial	PECAM1
	Other databases
	Probes
	Litterature
PubMed	230 Pubmed reference(s) in Entrez
CoreMine	PECAM1
GoPubMed	PECAM1
iHOP	PECAM1

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

Updated	12-2014	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Feb 14 17:57:06 CET 2015

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