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PECAM1 (platelet/endothelial cell adhesion molecule 1)

Identity

Other namesCD31
CD31/EndoCAM
GPIIA'
PECA1
PECAM-1
endoCAM
HGNC (Hugo) PECAM1
LocusID (NCBI) 5175
Location 17q23.3
Location_base_pair Starts at 62396777 and ends at 62407083 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PECAM1   8823
Cards
Entrez_Gene (NCBI)PECAM1  5175  platelet/endothelial cell adhesion molecule 1
GeneCards (Weizmann)PECAM1
Ensembl hg19 (Hinxton) [Gene_View]  chr17:62396777-62407083 [Contig_View]  PECAM1 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr17:62396777-62407083 [Contig_View]  PECAM1 [Vega]
cBioPortalPECAM1
AceView (NCBI)PECAM1
Genatlas (Paris)PECAM1
WikiGenes5175
SOURCE (Princeton)PECAM1
Genomic and cartography
GoldenPath hg19 (UCSC)PECAM1  -     chr17:62396777-62407083 -  17q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PECAM1  -     17q23.3   [Description]    (hg38-Dec_2013)
EnsemblPECAM1 - 17q23.3 [CytoView hg19]  PECAM1 - 17q23.3 [CytoView hg38]
Mapping of homologs : NCBIPECAM1 [Mapview hg19]  PECAM1 [Mapview hg38]
OMIM173445   
Gene and transcription
Genbank (Entrez)AF281287 AF281288 AF281289 AF281290 AF281291
RefSeq transcript (Entrez)NM_000442
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NT_010783 NW_001838450 NW_004929407
Consensus coding sequences : CCDS (NCBI)PECAM1
Cluster EST : UnigeneHs.514412 [ NCBI ]
CGAP (NCI)Hs.514412
Alternative Splicing : Fast-db (Paris)GSHG0039312
Gene ExpressionPECAM1 [ NCBI-GEO ]     PECAM1 [ SEEK ]   PECAM1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16284 (Uniprot)
NextProtP16284  [Medical]
With graphics : InterProP16284
Splice isoforms : SwissVarP16284 (Swissvar)
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub   
Related proteins : CluSTrP16284
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)IG (SM00409)  
DMDM Disease mutations5175
Blocks (Seattle)P16284
PDB (SRS)2KY5   
PDB (PDBSum)2KY5   
PDB (IMB)2KY5   
PDB (RSDB)2KY5   
Peptide AtlasP16284
HPRD01425
IPIIPI00295618   IPI00470719   IPI00470720   IPI00914041   IPI01010172   IPI00871352   
Protein Interaction databases
DIP (DOE-UCLA)P16284
IntAct (EBI)P16284
BioGRIDPECAM1
IntegromeDBPECAM1
STRING (EMBL)PECAM1
Ontologies - Pathways
QuickGOP16284
Ontology : AmiGOplatelet degranulation  protein binding  extracellular space  plasma membrane  plasma membrane  phagocytosis  cell adhesion  signal transduction  blood coagulation  cell recognition  integral component of membrane  cell junction  platelet activation  extracellular matrix organization  platelet alpha granule membrane  leukocyte migration  diapedesis  extracellular vesicular exosome  glomerular endothelium development  
Ontology : EGO-EBIplatelet degranulation  protein binding  extracellular space  plasma membrane  plasma membrane  phagocytosis  cell adhesion  signal transduction  blood coagulation  cell recognition  integral component of membrane  cell junction  platelet activation  extracellular matrix organization  platelet alpha granule membrane  leukocyte migration  diapedesis  extracellular vesicular exosome  glomerular endothelium development  
Pathways : BIOCARTANeutrophil and Its Surface Molecules [Genes]    Adhesion and Diapedesis of Granulocytes [Genes]    Adhesion Molecules on Lymphocyte [Genes]    Monocyte and its Surface Molecules [Genes]    Adhesion and Diapedesis of Lymphocytes [Genes]    Cell to Cell Adhesion Signaling [Genes]   
Pathways : KEGGCell adhesion molecules (CAMs)    Leukocyte transendothelial migration    Malaria   
Protein Interaction DatabasePECAM1
DoCM (Curated mutations)PECAM1
Wikipedia pathwaysPECAM1
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerPECAM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PECAM1
dbVarPECAM1
ClinVarPECAM1
1000_GenomesPECAM1 
Exome Variant ServerPECAM1
SNP (GeneSNP Utah)PECAM1
SNP : HGBasePECAM1
Genetic variants : HAPMAPPECAM1
Genomic VariantsPECAM1  PECAM1 [DGVbeta]
Mutations
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:62396777-62407083
Mutations and Diseases : HGMDPECAM1
OMIM173445   
MedgenPECAM1
NextProtP16284 [Medical]
GENETestsPECAM1
Disease Genetic AssociationPECAM1
Huge Navigator PECAM1 [HugePedia]  PECAM1 [HugeCancerGEM]
snp3D : Map Gene to Disease5175
DGIdb (Drug Gene Interaction db)PECAM1
General knowledge
Homologs : HomoloGenePECAM1
Homology/Alignments : Family Browser (UCSC)PECAM1
Phylogenetic Trees/Animal Genes : TreeFamPECAM1
Chemical/Protein Interactions : CTD5175
Chemical/Pharm GKB GenePA33167
Clinical trialPECAM1
Other databases
Probes
Litterature
PubMed230 Pubmed reference(s) in Entrez
CoreMinePECAM1
GoPubMedPECAM1
iHOPPECAM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 00:47:00 CET 2014

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