Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PKN3 (protein kinase N3)

Identity

Alias_symbol (synonym)PKNbeta
UTDP4-1
Other alias
HGNC (Hugo) PKN3
LocusID (NCBI) 29941
Atlas_Id 46487
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 131464783 and ends at 131483199 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PKN3   17999
Cards
Entrez_Gene (NCBI)PKN3  29941  protein kinase N3
AliasesUTDP4-1
GeneCards (Weizmann)PKN3
Ensembl hg19 (Hinxton)ENSG00000160447 [Gene_View]  chr9:131464783-131483199 [Contig_View]  PKN3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000160447 [Gene_View]  chr9:131464783-131483199 [Contig_View]  PKN3 [Vega]
ICGC DataPortalENSG00000160447
TCGA cBioPortalPKN3
AceView (NCBI)PKN3
Genatlas (Paris)PKN3
WikiGenes29941
SOURCE (Princeton)PKN3
Genetics Home Reference (NIH)PKN3
Genomic and cartography
GoldenPath hg19 (UCSC)PKN3  -     chr9:131464783-131483199 +  9q34.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PKN3  -     9q34.11   [Description]    (hg38-Dec_2013)
EnsemblPKN3 - 9q34.11 [CytoView hg19]  PKN3 - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBIPKN3 [Mapview hg19]  PKN3 [Mapview hg38]
OMIM610714   
Gene and transcription
Genbank (Entrez)AB019692 AI741632 AK097535 BC023327 BC032794
RefSeq transcript (Entrez)NM_001317926 NM_013355
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008470 NW_004929366
Consensus coding sequences : CCDS (NCBI)PKN3
Cluster EST : UnigeneHs.674749 [ NCBI ]
CGAP (NCI)Hs.674749
Alternative Splicing GalleryENSG00000160447
Gene ExpressionPKN3 [ NCBI-GEO ]   PKN3 [ EBI - ARRAY_EXPRESS ]   PKN3 [ SEEK ]   PKN3 [ MEM ]
Gene Expression Viewer (FireBrowse)PKN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29941
GTEX Portal (Tissue expression)PKN3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P5Z2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P5Z2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P5Z2
Splice isoforms : SwissVarQ6P5Z2
Catalytic activity : Enzyme2.7.11.13 [ Enzyme-Expasy ]   2.7.11.132.7.11.13 [ IntEnz-EBI ]   2.7.11.13 [ BRENDA ]   2.7.11.13 [ KEGG ]   
PhosPhoSitePlusQ6P5Z2
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)AGC-kinase_C    C2_dom    HR1_rho-bd    Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)HR1 (PF02185)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam02185    pfam00069   
Domain families : Smart (EMBL)C2 (SM00239)  Hr1 (SM00742)  S_TK_X (SM00133)  S_TKc (SM00220)  
Conserved Domain (NCBI)PKN3
DMDM Disease mutations29941
Blocks (Seattle)PKN3
SuperfamilyQ6P5Z2
Human Protein AtlasENSG00000160447
Peptide AtlasQ6P5Z2
HPRD17856
IPIIPI00413780   
Protein Interaction databases
DIP (DOE-UCLA)Q6P5Z2
IntAct (EBI)Q6P5Z2
FunCoupENSG00000160447
BioGRIDPKN3
STRING (EMBL)PKN3
ZODIACPKN3
Ontologies - Pathways
QuickGOQ6P5Z2
Ontology : AmiGOprotein kinase activity  protein serine/threonine kinase activity  protein kinase C activity  protein binding  ATP binding  nucleus  Golgi apparatus  protein phosphorylation  signal transduction  epithelial cell migration  peptidyl-serine phosphorylation  intracellular signal transduction  perinuclear region of cytoplasm  
Ontology : EGO-EBIprotein kinase activity  protein serine/threonine kinase activity  protein kinase C activity  protein binding  ATP binding  nucleus  Golgi apparatus  protein phosphorylation  signal transduction  epithelial cell migration  peptidyl-serine phosphorylation  intracellular signal transduction  perinuclear region of cytoplasm  
Pathways : KEGGPI3K-Akt signaling pathway    Salmonella infection   
NDEx NetworkPKN3
Atlas of Cancer Signalling NetworkPKN3
Wikipedia pathwaysPKN3
Orthology - Evolution
OrthoDB29941
GeneTree (enSembl)ENSG00000160447
Phylogenetic Trees/Animal Genes : TreeFamPKN3
HOVERGENQ6P5Z2
HOGENOMQ6P5Z2
Homologs : HomoloGenePKN3
Homology/Alignments : Family Browser (UCSC)PKN3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPKN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PKN3
dbVarPKN3
ClinVarPKN3
1000_GenomesPKN3 
Exome Variant ServerPKN3
ExAC (Exome Aggregation Consortium)PKN3 (select the gene name)
Genetic variants : HAPMAP29941
Genomic Variants (DGV)PKN3 [DGVbeta]
DECIPHER (Syndromes)9:131464783-131483199  ENSG00000160447
CONAN: Copy Number AnalysisPKN3 
Mutations
ICGC Data PortalPKN3 
TCGA Data PortalPKN3 
Broad Tumor PortalPKN3
OASIS PortalPKN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPKN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPKN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PKN3
DgiDB (Drug Gene Interaction Database)PKN3
DoCM (Curated mutations)PKN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PKN3 (select a term)
intoGenPKN3
Cancer3DPKN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610714   
Orphanet
MedgenPKN3
Genetic Testing Registry PKN3
NextProtQ6P5Z2 [Medical]
TSGene29941
GENETestsPKN3
Huge Navigator PKN3 [HugePedia]
snp3D : Map Gene to Disease29941
BioCentury BCIQPKN3
ClinGenPKN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29941
Chemical/Pharm GKB GenePA134919098
Clinical trialPKN3
Miscellaneous
canSAR (ICR)PKN3 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePKN3
EVEXPKN3
GoPubMedPKN3
iHOPPKN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:14:31 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.