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POLL (DNA polymerase lambda)

Identity

Alias_namespolymerase (DNA directed), lambda
polymerase (DNA) lambda
Other aliasBETAN
POLKAPPA
HGNC (Hugo) POLL
LocusID (NCBI) 27343
Atlas_Id 41778
Location 10q24.32  [Link to chromosome band 10q24]
Location_base_pair Starts at 101578882 and ends at 101588270 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)POLL   9184
Cards
Entrez_Gene (NCBI)POLL  27343  DNA polymerase lambda
AliasesBETAN; POLKAPPA
GeneCards (Weizmann)POLL
Ensembl hg19 (Hinxton)ENSG00000166169 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166169 [Gene_View]  chr10:101578882-101588270 [Contig_View]  POLL [Vega]
ICGC DataPortalENSG00000166169
TCGA cBioPortalPOLL
AceView (NCBI)POLL
Genatlas (Paris)POLL
WikiGenes27343
SOURCE (Princeton)POLL
Genetics Home Reference (NIH)POLL
Genomic and cartography
GoldenPath hg38 (UCSC)POLL  -     chr10:101578882-101588270 -  10q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POLL  -     10q24.32   [Description]    (hg19-Feb_2009)
EnsemblPOLL - 10q24.32 [CytoView hg19]  POLL - 10q24.32 [CytoView hg38]
Mapping of homologs : NCBIPOLL [Mapview hg19]  POLL [Mapview hg38]
OMIM606343   
Gene and transcription
Genbank (Entrez)AF161019 AF218027 AF283478 AJ131890 AJ844641
RefSeq transcript (Entrez)NM_001174084 NM_001174085 NM_001308382 NM_013274
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POLL
Cluster EST : UnigeneHs.523230 [ NCBI ]
CGAP (NCI)Hs.523230
Alternative Splicing GalleryENSG00000166169
Gene ExpressionPOLL [ NCBI-GEO ]   POLL [ EBI - ARRAY_EXPRESS ]   POLL [ SEEK ]   POLL [ MEM ]
Gene Expression Viewer (FireBrowse)POLL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27343
GTEX Portal (Tissue expression)POLL
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UGP5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UGP5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UGP5
Splice isoforms : SwissVarQ9UGP5
PhosPhoSitePlusQ9UGP5
Domaine pattern : Prosite (Expaxy)BRCT (PS50172)    DNA_POLYMERASE_X (PS00522)   
Domains : Interpro (EBI)BRCT_dom    DNA-dir_DNA_pol_X    DNA_pol-X_BS    DNA_pol_b-like_N    DNA_pol_B_palm_palm    DNA_pol_lambd_fingers_domain    DNA_pol_X    DNA_pol_X_beta-like    DNA_pol_X_lyase_dom    PolB_thumb   
Domain families : Pfam (Sanger)DNA_pol_B_palm (PF14792)    DNA_pol_B_thumb (PF14791)    DNA_pol_lambd_f (PF10391)    HHH_8 (PF14716)   
Domain families : Pfam (NCBI)pfam14792    pfam14791    pfam10391    pfam14716   
Domain families : Smart (EMBL)POLXc (SM00483)  
Conserved Domain (NCBI)POLL
DMDM Disease mutations27343
Blocks (Seattle)POLL
PDB (SRS)###############################################################################################################################################################################################################################################################   
PDB (PDBSum)###############################################################################################################################################################################################################################################################   
PDB (IMB)###############################################################################################################################################################################################################################################################   
PDB (RSDB)###############################################################################################################################################################################################################################################################   
Structural Biology KnowledgeBase###############################################################################################################################################################################################################################################################   
SCOP (Structural Classification of Proteins)###############################################################################################################################################################################################################################################################   
CATH (Classification of proteins structures)###############################################################################################################################################################################################################################################################   
SuperfamilyQ9UGP5
Human Protein AtlasENSG00000166169
Peptide AtlasQ9UGP5
HPRD09394
IPIIPI00002284   IPI00909367   IPI00553108   IPI00030374   IPI00643257   IPI00643025   IPI00644510   IPI00644963   IPI00644085   IPI00640708   IPI00646337   IPI00647856   
Protein Interaction databases
DIP (DOE-UCLA)Q9UGP5
IntAct (EBI)Q9UGP5
FunCoupENSG00000166169
BioGRIDPOLL
STRING (EMBL)POLL
ZODIACPOLL
Ontologies - Pathways
QuickGOQ9UGP5
Ontology : AmiGOdouble-strand break repair via homologous recombination  DNA binding  DNA-directed DNA polymerase activity  DNA-directed DNA polymerase activity  DNA-directed DNA polymerase activity  nucleus  nucleoplasm  DNA replication  base-excision repair, gap-filling  nucleotide-excision repair  double-strand break repair via nonhomologous end joining  double-strand break repair via nonhomologous end joining  somatic hypermutation of immunoglobulin genes  metal ion binding  5'-deoxyribose-5-phosphate lyase activity  DNA biosynthetic process  
Ontology : EGO-EBIdouble-strand break repair via homologous recombination  DNA binding  DNA-directed DNA polymerase activity  DNA-directed DNA polymerase activity  DNA-directed DNA polymerase activity  nucleus  nucleoplasm  DNA replication  base-excision repair, gap-filling  nucleotide-excision repair  double-strand break repair via nonhomologous end joining  double-strand break repair via nonhomologous end joining  somatic hypermutation of immunoglobulin genes  metal ion binding  5'-deoxyribose-5-phosphate lyase activity  DNA biosynthetic process  
Pathways : KEGGBase excision repair    Non-homologous end-joining   
NDEx NetworkPOLL
Atlas of Cancer Signalling NetworkPOLL
Wikipedia pathwaysPOLL
Orthology - Evolution
OrthoDB27343
GeneTree (enSembl)ENSG00000166169
Phylogenetic Trees/Animal Genes : TreeFamPOLL
HOVERGENQ9UGP5
HOGENOMQ9UGP5
Homologs : HomoloGenePOLL
Homology/Alignments : Family Browser (UCSC)POLL
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOLL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POLL
dbVarPOLL
ClinVarPOLL
1000_GenomesPOLL 
Exome Variant ServerPOLL
ExAC (Exome Aggregation Consortium)POLL (select the gene name)
Genetic variants : HAPMAP27343
Genomic Variants (DGV)POLL [DGVbeta]
DECIPHERPOLL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOLL 
Mutations
ICGC Data PortalPOLL 
TCGA Data PortalPOLL 
Broad Tumor PortalPOLL
OASIS PortalPOLL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOLL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOLL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POLL
DgiDB (Drug Gene Interaction Database)POLL
DoCM (Curated mutations)POLL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POLL (select a term)
intoGenPOLL
Cancer3DPOLL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606343   
Orphanet
MedgenPOLL
Genetic Testing Registry POLL
NextProtQ9UGP5 [Medical]
TSGene27343
GENETestsPOLL
Target ValidationPOLL
Huge Navigator POLL [HugePedia]
snp3D : Map Gene to Disease27343
BioCentury BCIQPOLL
ClinGenPOLL (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27343
Chemical/Pharm GKB GenePA33504
Clinical trialPOLL
Miscellaneous
canSAR (ICR)POLL (select the gene name)
Probes
Litterature
PubMed82 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOLL
EVEXPOLL
GoPubMedPOLL
iHOPPOLL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:50:15 CEST 2017

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