Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PON2 (paraoxonase 2)

Identity

Other alias-
HGNC (Hugo) PON2
LocusID (NCBI) 5445
Atlas_Id 51467
Location 7q21.3  [Link to chromosome band 7q21]
Location_base_pair Starts at 95404862 and ends at 95435072 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PON2   9205
Cards
Entrez_Gene (NCBI)PON2  5445  paraoxonase 2
Aliases
GeneCards (Weizmann)PON2
Ensembl hg19 (Hinxton)ENSG00000105854 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105854 [Gene_View]  chr7:95404862-95435072 [Contig_View]  PON2 [Vega]
ICGC DataPortalENSG00000105854
TCGA cBioPortalPON2
AceView (NCBI)PON2
Genatlas (Paris)PON2
WikiGenes5445
SOURCE (Princeton)PON2
Genetics Home Reference (NIH)PON2
Genomic and cartography
GoldenPath hg38 (UCSC)PON2  -     chr7:95404862-95435072 -  7q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PON2  -     7q21.3   [Description]    (hg19-Feb_2009)
EnsemblPON2 - 7q21.3 [CytoView hg19]  PON2 - 7q21.3 [CytoView hg38]
Mapping of homologs : NCBIPON2 [Mapview hg19]  PON2 [Mapview hg38]
OMIM602447   
Gene and transcription
Genbank (Entrez)AB102891 AF001601 AF001602 AK054688 AK291103
RefSeq transcript (Entrez)NM_000305 NM_001018161
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PON2
Cluster EST : UnigeneHs.744912 [ NCBI ]
CGAP (NCI)Hs.744912
Alternative Splicing GalleryENSG00000105854
Gene ExpressionPON2 [ NCBI-GEO ]   PON2 [ EBI - ARRAY_EXPRESS ]   PON2 [ SEEK ]   PON2 [ MEM ]
Gene Expression Viewer (FireBrowse)PON2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5445
GTEX Portal (Tissue expression)PON2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15165   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15165  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15165
Splice isoforms : SwissVarQ15165
Catalytic activity : Enzyme3.1.1.2 [ Enzyme-Expasy ]   3.1.1.23.1.1.2 [ IntEnz-EBI ]   3.1.1.2 [ BRENDA ]   3.1.1.2 [ KEGG ]   
PhosPhoSitePlusQ15165
Domains : Interpro (EBI)6-blade_b-propeller_TolB-like    Arylesterase    Paraoxonase2   
Domain families : Pfam (Sanger)Arylesterase (PF01731)   
Domain families : Pfam (NCBI)pfam01731   
Conserved Domain (NCBI)PON2
DMDM Disease mutations5445
Blocks (Seattle)PON2
SuperfamilyQ15165
Human Protein AtlasENSG00000105854
Peptide AtlasQ15165
HPRD03903
IPIIPI00014958   IPI00742670   IPI00844348   IPI00976213   IPI00290945   IPI00925904   
Protein Interaction databases
DIP (DOE-UCLA)Q15165
IntAct (EBI)Q15165
FunCoupENSG00000105854
BioGRIDPON2
STRING (EMBL)PON2
ZODIACPON2
Ontologies - Pathways
QuickGOQ15165
Ontology : AmiGOarylesterase activity  extracellular region  nucleus  mitochondrion  lysosome  plasma membrane  response to oxidative stress  response to toxic substance  lipoxygenase pathway  aromatic compound catabolic process  identical protein binding  metal ion binding  acyl-L-homoserine-lactone lactonohydrolase activity  
Ontology : EGO-EBIarylesterase activity  extracellular region  nucleus  mitochondrion  lysosome  plasma membrane  response to oxidative stress  response to toxic substance  lipoxygenase pathway  aromatic compound catabolic process  identical protein binding  metal ion binding  acyl-L-homoserine-lactone lactonohydrolase activity  
NDEx NetworkPON2
Atlas of Cancer Signalling NetworkPON2
Wikipedia pathwaysPON2
Orthology - Evolution
OrthoDB5445
GeneTree (enSembl)ENSG00000105854
Phylogenetic Trees/Animal Genes : TreeFamPON2
HOVERGENQ15165
HOGENOMQ15165
Homologs : HomoloGenePON2
Homology/Alignments : Family Browser (UCSC)PON2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPON2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PON2
dbVarPON2
ClinVarPON2
1000_GenomesPON2 
Exome Variant ServerPON2
ExAC (Exome Aggregation Consortium)PON2 (select the gene name)
Genetic variants : HAPMAP5445
Genomic Variants (DGV)PON2 [DGVbeta]
DECIPHERPON2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPON2 
Mutations
ICGC Data PortalPON2 
TCGA Data PortalPON2 
Broad Tumor PortalPON2
OASIS PortalPON2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPON2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPON2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PON2
DgiDB (Drug Gene Interaction Database)PON2
DoCM (Curated mutations)PON2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PON2 (select a term)
intoGenPON2
Cancer3DPON2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602447   
Orphanet106   
MedgenPON2
Genetic Testing Registry PON2
NextProtQ15165 [Medical]
TSGene5445
GENETestsPON2
Huge Navigator PON2 [HugePedia]
snp3D : Map Gene to Disease5445
BioCentury BCIQPON2
ClinGenPON2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5445
Chemical/Pharm GKB GenePA33530
Clinical trialPON2
Miscellaneous
canSAR (ICR)PON2 (select the gene name)
Probes
Litterature
PubMed196 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePON2
EVEXPON2
GoPubMedPON2
iHOPPON2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:32:05 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.