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PPP1CB (protein phosphatase 1, catalytic subunit, beta isozyme)

Identity

Other namesPP-1B
PP1B
PP1beta
PPP1CD
HGNC (Hugo) PPP1CB
LocusID (NCBI) 5500
Location 2p23.2
Location_base_pair Starts at 28974626 and ends at 29025806 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PPP1CB   9282
Cards
Entrez_Gene (NCBI)PPP1CB  5500  protein phosphatase 1, catalytic subunit, beta isozyme
GeneCards (Weizmann)PPP1CB
Ensembl (Hinxton)ENSG00000213639 [Gene_View]  chr2:28974626-29025806 [Contig_View]  PPP1CB [Vega]
AceView (NCBI)PPP1CB
Genatlas (Paris)PPP1CB
WikiGenes5500
SOURCE (Princeton)NM_002709 NM_206876 NM_206877
Genomic and cartography
GoldenPath (UCSC)PPP1CB  -  2p23.2   chr2:28974626-29025806 +  2p23.2   [Description]    (hg19-Feb_2009)
EnsemblPPP1CB - 2p23.2 [CytoView]
Mapping of homologs : NCBIPPP1CB [Mapview]
OMIM600590   
Gene and transcription
Genbank (Entrez)AF092905 AI147919 AK295957 AK303682 AK312329
RefSeq transcript (Entrez)NM_002709 NM_206876 NM_206877
RefSeq genomic (Entrez)AC_000134 NC_000002 NC_018913 NT_022184 NW_001838768 NW_004929300
Consensus coding sequences : CCDS (NCBI)PPP1CB
Cluster EST : UnigeneHs.702907 [ NCBI ]
CGAP (NCI)Hs.702907
Alternative Splicing : Fast-db (Paris)GSHG0016348
Alternative Splicing GalleryENSG00000213639
Gene ExpressionPPP1CB [ NCBI-GEO ]     PPP1CB [ SEEK ]   PPP1CB [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62140 (Uniprot)
NextProtP62140  [Medical]
With graphics : InterProP62140
Splice isoforms : SwissVarP62140 (Swissvar)
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)SER_THR_PHOSPHATASE (PS00125)   
Domains : Interpro (EBI)PEstase_dom    Ser/Thr-sp_prot-phosphatase   
Related proteins : CluSTrP62140
Domain families : Pfam (Sanger)Metallophos (PF00149)   
Domain families : Pfam (NCBI)pfam00149   
Domain families : Smart (EMBL)PP2Ac (SM00156)  
DMDM Disease mutations5500
Blocks (Seattle)P62140
Human Protein AtlasENSG00000213639
Peptide AtlasP62140
HPRD11792
IPIIPI00218236   IPI00894274   IPI00930380   IPI00892668   IPI00894333   IPI00894160   
Protein Interaction databases
DIP (DOE-UCLA)P62140
IntAct (EBI)P62140
FunCoupENSG00000213639
BioGRIDPPP1CB
InParanoidP62140
Interologous Interaction database P62140
IntegromeDBPPP1CB
STRING (EMBL)PPP1CB
Ontologies - Pathways
Ontology : AmiGOG2/M transition of mitotic cell cycle  protein phosphatase type 1 complex  mitotic cell cycle  protein binding  nucleoplasm  nucleolus  glycogen metabolic process  regulation of glycogen biosynthetic process  regulation of glycogen catabolic process  protein dephosphorylation  transforming growth factor beta receptor signaling pathway  myosin phosphatase activity  triglyceride catabolic process  protein kinase binding  regulation of cell adhesion  negative regulation of transforming growth factor beta receptor signaling pathway  glycogen granule  small molecule metabolic process  metal ion binding  myosin-light-chain-phosphatase activity  cell division  MLL5-L complex  PTW/PP1 phosphatase complex  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  protein phosphatase type 1 complex  mitotic cell cycle  protein binding  nucleoplasm  nucleolus  glycogen metabolic process  regulation of glycogen biosynthetic process  regulation of glycogen catabolic process  protein dephosphorylation  transforming growth factor beta receptor signaling pathway  myosin phosphatase activity  triglyceride catabolic process  protein kinase binding  regulation of cell adhesion  negative regulation of transforming growth factor beta receptor signaling pathway  glycogen granule  small molecule metabolic process  metal ion binding  myosin-light-chain-phosphatase activity  cell division  MLL5-L complex  PTW/PP1 phosphatase complex  
Pathways : KEGGmRNA surveillance pathway    Oocyte meiosis    Adrenergic signaling in cardiomyocytes    Vascular smooth muscle contraction    Hippo signaling pathway    Focal adhesion    Long-term potentiation    Dopaminergic synapse    Regulation of actin cytoskeleton    Insulin signaling pathway    Amphetamine addiction    Alcoholism    Herpes simplex infection    Proteoglycans in cancer   
REACTOMEPPP1CB
Protein Interaction DatabasePPP1CB
Wikipedia pathwaysPPP1CB
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PPP1CB
SNP (GeneSNP Utah)PPP1CB
SNP : HGBasePPP1CB
Genetic variants : HAPMAPPPP1CB
1000_GenomesPPP1CB 
ICGC programENSG00000213639 
Somatic Mutations in Cancer : COSMICPPP1CB 
CONAN: Copy Number AnalysisPPP1CB 
Mutations and Diseases : HGMDPPP1CB
OMIM600590   
GENETestsPPP1CB
Disease Genetic AssociationPPP1CB
Huge Navigator PPP1CB [HugePedia]  PPP1CB [HugeCancerGEM]
Genomic VariantsPPP1CB  PPP1CB [DGVbeta]
Exome VariantPPP1CB
dbVarPPP1CB
ClinVarPPP1CB
snp3D : Map Gene to Disease5500
General knowledge
Homologs : HomoloGenePPP1CB
Homology/Alignments : Family Browser (UCSC)PPP1CB
Phylogenetic Trees/Animal Genes : TreeFamPPP1CB
Chemical/Protein Interactions : CTD5500
Chemical/Pharm GKB GenePA33610
Clinical trialPPP1CB
Cancer Resource (Charite)ENSG00000213639
Other databases
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
CoreMinePPP1CB
iHOPPPP1CB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 17:04:10 CEST 2014

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