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PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2)

Identity

Alias_namesprotein phosphatase 1
Alias_symbol (synonym)IPP2
Other aliasIPP-2
HGNC (Hugo) PPP1R2
LocusID (NCBI) 5504
Atlas_Id 46630
Location 3q29  [Link to chromosome band 3q29]
Location_base_pair Starts at 195514422 and ends at 195543401 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
cytochrome_b () / PPP1R2 (3q29)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP1R2   9288
Cards
Entrez_Gene (NCBI)PPP1R2  5504  protein phosphatase 1 regulatory inhibitor subunit 2
AliasesIPP-2; IPP2
GeneCards (Weizmann)PPP1R2
Ensembl hg19 (Hinxton)ENSG00000184203 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184203 [Gene_View]  chr3:195514422-195543401 [Contig_View]  PPP1R2 [Vega]
ICGC DataPortalENSG00000184203
TCGA cBioPortalPPP1R2
AceView (NCBI)PPP1R2
Genatlas (Paris)PPP1R2
WikiGenes5504
SOURCE (Princeton)PPP1R2
Genetics Home Reference (NIH)PPP1R2
Genomic and cartography
GoldenPath hg38 (UCSC)PPP1R2  -     chr3:195514422-195543401 -  3q29   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP1R2  -     3q29   [Description]    (hg19-Feb_2009)
EnsemblPPP1R2 - 3q29 [CytoView hg19]  PPP1R2 - 3q29 [CytoView hg38]
Mapping of homologs : NCBIPPP1R2 [Mapview hg19]  PPP1R2 [Mapview hg38]
OMIM601792   
Gene and transcription
Genbank (Entrez)AA259068 AI638626 AJ133812 AY063767 BC007655
RefSeq transcript (Entrez)NM_001291504 NM_001291505 NM_001316325 NM_006241
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP1R2
Cluster EST : UnigeneHs.706920 [ NCBI ]
CGAP (NCI)Hs.706920
Alternative Splicing GalleryENSG00000184203
Gene ExpressionPPP1R2 [ NCBI-GEO ]   PPP1R2 [ EBI - ARRAY_EXPRESS ]   PPP1R2 [ SEEK ]   PPP1R2 [ MEM ]
Gene Expression Viewer (FireBrowse)PPP1R2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5504
GTEX Portal (Tissue expression)PPP1R2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41236   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41236  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41236
Splice isoforms : SwissVarP41236
PhosPhoSitePlusP41236
Domains : Interpro (EBI)PPI-2   
Domain families : Pfam (Sanger)IPP-2 (PF04979)   
Domain families : Pfam (NCBI)pfam04979   
Conserved Domain (NCBI)PPP1R2
DMDM Disease mutations5504
Blocks (Seattle)PPP1R2
SuperfamilyP41236
Human Protein AtlasENSG00000184203
Peptide AtlasP41236
HPRD03478
IPIIPI00220402   IPI00927947   IPI00924602   IPI00924800   
Protein Interaction databases
DIP (DOE-UCLA)P41236
IntAct (EBI)P41236
FunCoupENSG00000184203
BioGRIDPPP1R2
STRING (EMBL)PPP1R2
ZODIACPPP1R2
Ontologies - Pathways
QuickGOP41236
Ontology : AmiGOprotein phosphatase type 1 complex  protein serine/threonine phosphatase inhibitor activity  protein binding  nucleoplasm  cytosol  glycogen metabolic process  generation of precursor metabolites and energy  regulation of signal transduction  negative regulation of catalytic activity  regulation of phosphoprotein phosphatase activity  
Ontology : EGO-EBIprotein phosphatase type 1 complex  protein serine/threonine phosphatase inhibitor activity  protein binding  nucleoplasm  cytosol  glycogen metabolic process  generation of precursor metabolites and energy  regulation of signal transduction  negative regulation of catalytic activity  regulation of phosphoprotein phosphatase activity  
NDEx NetworkPPP1R2
Atlas of Cancer Signalling NetworkPPP1R2
Wikipedia pathwaysPPP1R2
Orthology - Evolution
OrthoDB5504
GeneTree (enSembl)ENSG00000184203
Phylogenetic Trees/Animal Genes : TreeFamPPP1R2
HOVERGENP41236
HOGENOMP41236
Homologs : HomoloGenePPP1R2
Homology/Alignments : Family Browser (UCSC)PPP1R2
Gene fusions - Rearrangements
Fusion Cancer (Beijing)cytochrome_b [PPP1R2]  -  3q29 [FUSC002793]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP1R2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP1R2
dbVarPPP1R2
ClinVarPPP1R2
1000_GenomesPPP1R2 
Exome Variant ServerPPP1R2
ExAC (Exome Aggregation Consortium)PPP1R2 (select the gene name)
Genetic variants : HAPMAP5504
Genomic Variants (DGV)PPP1R2 [DGVbeta]
DECIPHERPPP1R2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP1R2 
Mutations
ICGC Data PortalPPP1R2 
TCGA Data PortalPPP1R2 
Broad Tumor PortalPPP1R2
OASIS PortalPPP1R2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP1R2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP1R2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP1R2
DgiDB (Drug Gene Interaction Database)PPP1R2
DoCM (Curated mutations)PPP1R2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP1R2 (select a term)
intoGenPPP1R2
Cancer3DPPP1R2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601792   
Orphanet
MedgenPPP1R2
Genetic Testing Registry PPP1R2
NextProtP41236 [Medical]
TSGene5504
GENETestsPPP1R2
Huge Navigator PPP1R2 [HugePedia]
snp3D : Map Gene to Disease5504
BioCentury BCIQPPP1R2
ClinGenPPP1R2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5504
Chemical/Pharm GKB GenePA33641
Clinical trialPPP1R2
Miscellaneous
canSAR (ICR)PPP1R2 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP1R2
EVEXPPP1R2
GoPubMedPPP1R2
iHOPPPP1R2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:32:23 CEST 2017

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