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PPP4R2 (protein phosphatase 4 regulatory subunit 2)

Identity

Alias_namesprotein phosphatase 4
Other aliasPP4R2
HGNC (Hugo) PPP4R2
LocusID (NCBI) 151987
Atlas_Id 46991
Location 3p13  [Link to chromosome band 3p13]
Location_base_pair Starts at 72996785 and ends at 73069201 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HNRNPA2B1 (7p15.2) / PPP4R2 (3p13)PPP4R2 (3p13) / FOXP1 (3p13)PPP4R2 (3p13) / NCL (2q37.1)
ZCWPW2 (3p24.1) / PPP4R2 (3p13)PPP4R2 3p13 / FOXP1 3p13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PPP4R2   18296
Cards
Entrez_Gene (NCBI)PPP4R2  151987  protein phosphatase 4 regulatory subunit 2
AliasesPP4R2
GeneCards (Weizmann)PPP4R2
Ensembl hg19 (Hinxton)ENSG00000163605 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163605 [Gene_View]  chr3:72996785-73069201 [Contig_View]  PPP4R2 [Vega]
ICGC DataPortalENSG00000163605
TCGA cBioPortalPPP4R2
AceView (NCBI)PPP4R2
Genatlas (Paris)PPP4R2
WikiGenes151987
SOURCE (Princeton)PPP4R2
Genetics Home Reference (NIH)PPP4R2
Genomic and cartography
GoldenPath hg38 (UCSC)PPP4R2  -     chr3:72996785-73069201 +  3p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PPP4R2  -     3p13   [Description]    (hg19-Feb_2009)
EnsemblPPP4R2 - 3p13 [CytoView hg19]  PPP4R2 - 3p13 [CytoView hg38]
Mapping of homologs : NCBIPPP4R2 [Mapview hg19]  PPP4R2 [Mapview hg38]
OMIM613822   
Gene and transcription
Genbank (Entrez)AF327345 AJ271448 AK289901 AL833216 BC100281
RefSeq transcript (Entrez)NM_001318025 NM_001318026 NM_001318027 NM_001318028 NM_174907
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PPP4R2
Cluster EST : UnigeneHs.431092 [ NCBI ]
CGAP (NCI)Hs.431092
Alternative Splicing GalleryENSG00000163605
Gene ExpressionPPP4R2 [ NCBI-GEO ]   PPP4R2 [ EBI - ARRAY_EXPRESS ]   PPP4R2 [ SEEK ]   PPP4R2 [ MEM ]
Gene Expression Viewer (FireBrowse)PPP4R2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)151987
GTEX Portal (Tissue expression)PPP4R2
Human Protein AtlasENSG00000163605-PPP4R2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NY27   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NY27  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NY27
Splice isoforms : SwissVarQ9NY27
PhosPhoSitePlusQ9NY27
Domains : Interpro (EBI)PPP4R2   
Domain families : Pfam (Sanger)PPP4R2 (PF09184)   
Domain families : Pfam (NCBI)pfam09184   
Conserved Domain (NCBI)PPP4R2
DMDM Disease mutations151987
Blocks (Seattle)PPP4R2
SuperfamilyQ9NY27
Human Protein Atlas [tissue]ENSG00000163605-PPP4R2 [tissue]
Peptide AtlasQ9NY27
HPRD11453
IPIIPI00103654   IPI00746062   IPI00856016   IPI00947527   IPI00946635   IPI00947087   IPI00947364   
Protein Interaction databases
DIP (DOE-UCLA)Q9NY27
IntAct (EBI)Q9NY27
FunCoupENSG00000163605
BioGRIDPPP4R2
STRING (EMBL)PPP4R2
ZODIACPPP4R2
Ontologies - Pathways
QuickGOQ9NY27
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  centrosome  mRNA processing  cellular protein modification process  RNA splicing  regulation of double-strand break repair via homologous recombination  protein phosphatase regulator activity  protein phosphatase 4 complex  protein binding, bridging  regulation of catalytic activity  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  centrosome  mRNA processing  cellular protein modification process  RNA splicing  regulation of double-strand break repair via homologous recombination  protein phosphatase regulator activity  protein phosphatase 4 complex  protein binding, bridging  regulation of catalytic activity  
NDEx NetworkPPP4R2
Atlas of Cancer Signalling NetworkPPP4R2
Wikipedia pathwaysPPP4R2
Orthology - Evolution
OrthoDB151987
GeneTree (enSembl)ENSG00000163605
Phylogenetic Trees/Animal Genes : TreeFamPPP4R2
HOVERGENQ9NY27
HOGENOMQ9NY27
Homologs : HomoloGenePPP4R2
Homology/Alignments : Family Browser (UCSC)PPP4R2
Gene fusions - Rearrangements
Fusion: TCGA_MDACCPPP4R2 3p13 FOXP1 3p13 BRCA
Tumor Fusion PortalPPP4R2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPPP4R2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP4R2
dbVarPPP4R2
ClinVarPPP4R2
1000_GenomesPPP4R2 
Exome Variant ServerPPP4R2
ExAC (Exome Aggregation Consortium)ENSG00000163605
GNOMAD BrowserENSG00000163605
Genetic variants : HAPMAP151987
Genomic Variants (DGV)PPP4R2 [DGVbeta]
DECIPHERPPP4R2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPPP4R2 
Mutations
ICGC Data PortalPPP4R2 
TCGA Data PortalPPP4R2 
Broad Tumor PortalPPP4R2
OASIS PortalPPP4R2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPPP4R2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPPP4R2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PPP4R2
DgiDB (Drug Gene Interaction Database)PPP4R2
DoCM (Curated mutations)PPP4R2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PPP4R2 (select a term)
intoGenPPP4R2
Cancer3DPPP4R2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613822   
Orphanet
DisGeNETPPP4R2
MedgenPPP4R2
Genetic Testing Registry PPP4R2
NextProtQ9NY27 [Medical]
TSGene151987
GENETestsPPP4R2
Target ValidationPPP4R2
Huge Navigator PPP4R2 [HugePedia]
snp3D : Map Gene to Disease151987
BioCentury BCIQPPP4R2
ClinGenPPP4R2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD151987
Chemical/Pharm GKB GenePA38520
Clinical trialPPP4R2
Miscellaneous
canSAR (ICR)PPP4R2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePPP4R2
EVEXPPP4R2
GoPubMedPPP4R2
iHOPPPP4R2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:30:03 CET 2017

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