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PPP6C (protein phosphatase 6, catalytic subunit)

Identity

Other namesPP6
PP6C
HGNC (Hugo) PPP6C
LocusID (NCBI) 5537
Location 9q33.3
Location_base_pair Starts at 127908852 and ends at 127952218 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PPP6C   9323
Cards
Entrez_Gene (NCBI)PPP6C  5537  protein phosphatase 6, catalytic subunit
GeneCards (Weizmann)PPP6C
Ensembl hg19 (Hinxton)ENSG00000119414 [Gene_View]  chr9:127908852-127952218 [Contig_View]  PPP6C [Vega]
Ensembl hg38 (Hinxton)ENSG00000119414 [Gene_View]  chr9:127908852-127952218 [Contig_View]  PPP6C [Vega]
ICGC DataPortalENSG00000119414
cBioPortalPPP6C
AceView (NCBI)PPP6C
Genatlas (Paris)PPP6C
WikiGenes5537
SOURCE (Princeton)PPP6C
Genomic and cartography
GoldenPath hg19 (UCSC)PPP6C  -     chr9:127908852-127952218 -  9q33.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PPP6C  -     9q33.3   [Description]    (hg38-Dec_2013)
EnsemblPPP6C - 9q33.3 [CytoView hg19]  PPP6C - 9q33.3 [CytoView hg38]
Mapping of homologs : NCBIPPP6C [Mapview hg19]  PPP6C [Mapview hg38]
OMIM612725   
Gene and transcription
Genbank (Entrez)AA251321 AF035158 AK295190 AK295752 AK299087
RefSeq transcript (Entrez)NM_001123355 NM_001123369 NM_002721
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NT_008470 NW_001839239 NW_004929366
Consensus coding sequences : CCDS (NCBI)PPP6C
Cluster EST : UnigeneHs.744091 [ NCBI ]
CGAP (NCI)Hs.744091
Alternative Splicing : Fast-db (Paris)GSHG0031156
Alternative Splicing GalleryENSG00000119414
Gene ExpressionPPP6C [ NCBI-GEO ]     PPP6C [ SEEK ]   PPP6C [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00743 (Uniprot)
NextProtO00743  [Medical]
With graphics : InterProO00743
Splice isoforms : SwissVarO00743 (Swissvar)
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)SER_THR_PHOSPHATASE (PS00125)   
Domains : Interpro (EBI)Calcineurin-like_PHP_apaH    Metallo-depent_PP-like    Ser/Thr-sp_prot-phosphatase   
Related proteins : CluSTrO00743
Domain families : Pfam (Sanger)Metallophos (PF00149)   
Domain families : Pfam (NCBI)pfam00149   
Domain families : Smart (EMBL)PP2Ac (SM00156)  
DMDM Disease mutations5537
Blocks (Seattle)O00743
Human Protein AtlasENSG00000119414
Peptide AtlasO00743
HPRD02141
IPIIPI00012970   IPI00890827   IPI00890743   IPI01012187   IPI00514237   
Protein Interaction databases
DIP (DOE-UCLA)O00743
IntAct (EBI)O00743
FunCoupENSG00000119414
BioGRIDPPP6C
IntegromeDBPPP6C
STRING (EMBL)PPP6C
Ontologies - Pathways
QuickGOO00743
Ontology : AmiGOG1/S transition of mitotic cell cycle  protein serine/threonine phosphatase activity  protein binding  cytosol  protein dephosphorylation  metal ion binding  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  protein serine/threonine phosphatase activity  protein binding  cytosol  protein dephosphorylation  metal ion binding  
Protein Interaction DatabasePPP6C
DoCM (Curated mutations)PPP6C
Wikipedia pathwaysPPP6C
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerPPP6C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PPP6C
dbVarPPP6C
ClinVarPPP6C
1000_GenomesPPP6C 
Exome Variant ServerPPP6C
SNP (GeneSNP Utah)PPP6C
SNP : HGBasePPP6C
Genetic variants : HAPMAPPPP6C
Genomic VariantsPPP6C  PPP6C [DGVbeta]
Mutations
ICGC Data PortalENSG00000119414 
Somatic Mutations in Cancer : COSMICPPP6C 
CONAN: Copy Number AnalysisPPP6C 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)9:127908852-127952218
Mutations and Diseases : HGMDPPP6C
OMIM612725   
MedgenPPP6C
NextProtO00743 [Medical]
GENETestsPPP6C
Disease Genetic AssociationPPP6C
Huge Navigator PPP6C [HugePedia]  PPP6C [HugeCancerGEM]
snp3D : Map Gene to Disease5537
DGIdb (Drug Gene Interaction db)PPP6C
General knowledge
Homologs : HomoloGenePPP6C
Homology/Alignments : Family Browser (UCSC)PPP6C
Phylogenetic Trees/Animal Genes : TreeFamPPP6C
Chemical/Protein Interactions : CTD5537
Chemical/Pharm GKB GenePA33687
Clinical trialPPP6C
Cancer Resource (Charite)ENSG00000119414
Other databases
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
CoreMinePPP6C
GoPubMedPPP6C
iHOPPPP6C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 00:56:52 CET 2014

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