Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PROM2 (prominin 2)

Identity

Other aliasPROML2
HGNC (Hugo) PROM2
LocusID (NCBI) 150696
Atlas_Id 49882
Location 2q11.1  [Link to chromosome band 2q11]
Location_base_pair Starts at 95274448 and ends at 95291307 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PROM2 (2q11.1) / PROM2 (2q11.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PROM2   20685
Cards
Entrez_Gene (NCBI)PROM2  150696  prominin 2
AliasesPROML2
GeneCards (Weizmann)PROM2
Ensembl hg19 (Hinxton)ENSG00000155066 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155066 [Gene_View]  chr2:95274448-95291307 [Contig_View]  PROM2 [Vega]
ICGC DataPortalENSG00000155066
TCGA cBioPortalPROM2
AceView (NCBI)PROM2
Genatlas (Paris)PROM2
WikiGenes150696
SOURCE (Princeton)PROM2
Genetics Home Reference (NIH)PROM2
Genomic and cartography
GoldenPath hg38 (UCSC)PROM2  -     chr2:95274448-95291307 +  2q11.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PROM2  -     2q11.1   [Description]    (hg19-Feb_2009)
EnsemblPROM2 - 2q11.1 [CytoView hg19]  PROM2 - 2q11.1 [CytoView hg38]
Mapping of homologs : NCBIPROM2 [Mapview hg19]  PROM2 [Mapview hg38]
OMIM617160   
Gene and transcription
Genbank (Entrez)AF245303 AF245304 AI928825 AK026052 AK091175
RefSeq transcript (Entrez)NM_001165977 NM_001165978 NM_001321070 NM_144707
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PROM2
Cluster EST : UnigeneHs.469313 [ NCBI ]
CGAP (NCI)Hs.469313
Alternative Splicing GalleryENSG00000155066
Gene ExpressionPROM2 [ NCBI-GEO ]   PROM2 [ EBI - ARRAY_EXPRESS ]   PROM2 [ SEEK ]   PROM2 [ MEM ]
Gene Expression Viewer (FireBrowse)PROM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)150696
GTEX Portal (Tissue expression)PROM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N271   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N271  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N271
Splice isoforms : SwissVarQ8N271
PhosPhoSitePlusQ8N271
Domains : Interpro (EBI)Prominin   
Domain families : Pfam (Sanger)Prominin (PF05478)   
Domain families : Pfam (NCBI)pfam05478   
Conserved Domain (NCBI)PROM2
DMDM Disease mutations150696
Blocks (Seattle)PROM2
SuperfamilyQ8N271
Human Protein AtlasENSG00000155066
Peptide AtlasQ8N271
HPRD17912
IPIIPI00295988   IPI00177880   IPI00890804   IPI00925730   
Protein Interaction databases
DIP (DOE-UCLA)Q8N271
IntAct (EBI)Q8N271
FunCoupENSG00000155066
BioGRIDPROM2
STRING (EMBL)PROM2
ZODIACPROM2
Ontologies - Pathways
QuickGOQ8N271
Ontology : AmiGOpositive regulation of protein phosphorylation  integral component of plasma membrane  microvillus  cilium  cell surface  cholesterol binding  basolateral plasma membrane  apical plasma membrane  positive regulation of cell projection organization  cytoplasmic vesicle  microvillus membrane  cell projection  regulation of GTPase activity  microspike  membrane raft  negative regulation of pinocytosis  ciliary membrane  extracellular exosome  prominosome  regulation of clathrin-dependent endocytosis  negative regulation of caveolin-mediated endocytosis  
Ontology : EGO-EBIpositive regulation of protein phosphorylation  integral component of plasma membrane  microvillus  cilium  cell surface  cholesterol binding  basolateral plasma membrane  apical plasma membrane  positive regulation of cell projection organization  cytoplasmic vesicle  microvillus membrane  cell projection  regulation of GTPase activity  microspike  membrane raft  negative regulation of pinocytosis  ciliary membrane  extracellular exosome  prominosome  regulation of clathrin-dependent endocytosis  negative regulation of caveolin-mediated endocytosis  
NDEx NetworkPROM2
Atlas of Cancer Signalling NetworkPROM2
Wikipedia pathwaysPROM2
Orthology - Evolution
OrthoDB150696
GeneTree (enSembl)ENSG00000155066
Phylogenetic Trees/Animal Genes : TreeFamPROM2
HOVERGENQ8N271
HOGENOMQ8N271
Homologs : HomoloGenePROM2
Homology/Alignments : Family Browser (UCSC)PROM2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPROM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PROM2
dbVarPROM2
ClinVarPROM2
1000_GenomesPROM2 
Exome Variant ServerPROM2
ExAC (Exome Aggregation Consortium)PROM2 (select the gene name)
Genetic variants : HAPMAP150696
Genomic Variants (DGV)PROM2 [DGVbeta]
DECIPHERPROM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPROM2 
Mutations
ICGC Data PortalPROM2 
TCGA Data PortalPROM2 
Broad Tumor PortalPROM2
OASIS PortalPROM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPROM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPROM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PROM2
DgiDB (Drug Gene Interaction Database)PROM2
DoCM (Curated mutations)PROM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PROM2 (select a term)
intoGenPROM2
Cancer3DPROM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617160   
Orphanet
MedgenPROM2
Genetic Testing Registry PROM2
NextProtQ8N271 [Medical]
TSGene150696
GENETestsPROM2
Target ValidationPROM2
Huge Navigator PROM2 [HugePedia]
snp3D : Map Gene to Disease150696
BioCentury BCIQPROM2
ClinGenPROM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD150696
Chemical/Pharm GKB GenePA134861956
Clinical trialPROM2
Miscellaneous
canSAR (ICR)PROM2 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePROM2
EVEXPROM2
GoPubMedPROM2
iHOPPROM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:26:39 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.