Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PTGIR (prostaglandin I2 (prostacyclin) receptor (IP))

Identity

Alias_symbol (synonym)IP
Other aliasPRIPR
HGNC (Hugo) PTGIR
LocusID (NCBI) 5739
Atlas_Id 50074
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 46620468 and ends at 46625097 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PTGIR   9602
Cards
Entrez_Gene (NCBI)PTGIR  5739  prostaglandin I2 (prostacyclin) receptor (IP)
AliasesIP; PRIPR
GeneCards (Weizmann)PTGIR
Ensembl hg19 (Hinxton)ENSG00000160013 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160013 [Gene_View]  chr19:46620468-46625097 [Contig_View]  PTGIR [Vega]
ICGC DataPortalENSG00000160013
TCGA cBioPortalPTGIR
AceView (NCBI)PTGIR
Genatlas (Paris)PTGIR
WikiGenes5739
SOURCE (Princeton)PTGIR
Genetics Home Reference (NIH)PTGIR
Genomic and cartography
GoldenPath hg38 (UCSC)PTGIR  -     chr19:46620468-46625097 -  19q13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PTGIR  -     19q13.32   [Description]    (hg19-Feb_2009)
EnsemblPTGIR - 19q13.32 [CytoView hg19]  PTGIR - 19q13.32 [CytoView hg38]
Mapping of homologs : NCBIPTGIR [Mapview hg19]  PTGIR [Mapview hg38]
OMIM600022   
Gene and transcription
Genbank (Entrez)AK315278 AY242134 BC075814 BC110342 BQ185457
RefSeq transcript (Entrez)NM_000960
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PTGIR
Cluster EST : UnigeneHs.458324 [ NCBI ]
CGAP (NCI)Hs.458324
Alternative Splicing GalleryENSG00000160013
Gene ExpressionPTGIR [ NCBI-GEO ]   PTGIR [ EBI - ARRAY_EXPRESS ]   PTGIR [ SEEK ]   PTGIR [ MEM ]
Gene Expression Viewer (FireBrowse)PTGIR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5739
GTEX Portal (Tissue expression)PTGIR
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43119   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43119  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43119
Splice isoforms : SwissVarP43119
PhosPhoSitePlusP43119
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Prostanoid_rcpt    Prostglndn_IP_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)PTGIR
DMDM Disease mutations5739
Blocks (Seattle)PTGIR
SuperfamilyP43119
Human Protein AtlasENSG00000160013
Peptide AtlasP43119
HPRD08959
IPIIPI00016317   
Protein Interaction databases
DIP (DOE-UCLA)P43119
IntAct (EBI)P43119
FunCoupENSG00000160013
BioGRIDPTGIR
STRING (EMBL)PTGIR
ZODIACPTGIR
Ontologies - Pathways
QuickGOP43119
Ontology : AmiGOguanyl-nucleotide exchange factor activity  cytosol  plasma membrane  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-activating G-protein coupled receptor signaling pathway  cell-cell signaling  negative regulation of platelet-derived growth factor receptor signaling pathway  prostacyclin receptor activity  positive regulation of cAMP biosynthetic process  response to lipopolysaccharide  positive regulation of GTPase activity  positive regulation of cAMP-mediated signaling  negative regulation of smooth muscle cell proliferation  
Ontology : EGO-EBIguanyl-nucleotide exchange factor activity  cytosol  plasma membrane  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-activating G-protein coupled receptor signaling pathway  cell-cell signaling  negative regulation of platelet-derived growth factor receptor signaling pathway  prostacyclin receptor activity  positive regulation of cAMP biosynthetic process  response to lipopolysaccharide  positive regulation of GTPase activity  positive regulation of cAMP-mediated signaling  negative regulation of smooth muscle cell proliferation  
Pathways : BIOCARTAEicosanoid Metabolism [Genes]   
Pathways : KEGGNeuroactive ligand-receptor interaction    Vascular smooth muscle contraction   
NDEx NetworkPTGIR
Atlas of Cancer Signalling NetworkPTGIR
Wikipedia pathwaysPTGIR
Orthology - Evolution
OrthoDB5739
GeneTree (enSembl)ENSG00000160013
Phylogenetic Trees/Animal Genes : TreeFamPTGIR
HOVERGENP43119
HOGENOMP43119
Homologs : HomoloGenePTGIR
Homology/Alignments : Family Browser (UCSC)PTGIR
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTGIR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTGIR
dbVarPTGIR
ClinVarPTGIR
1000_GenomesPTGIR 
Exome Variant ServerPTGIR
ExAC (Exome Aggregation Consortium)PTGIR (select the gene name)
Genetic variants : HAPMAP5739
Genomic Variants (DGV)PTGIR [DGVbeta]
DECIPHERPTGIR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPTGIR 
Mutations
ICGC Data PortalPTGIR 
TCGA Data PortalPTGIR 
Broad Tumor PortalPTGIR
OASIS PortalPTGIR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPTGIR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPTGIR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PTGIR
DgiDB (Drug Gene Interaction Database)PTGIR
DoCM (Curated mutations)PTGIR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PTGIR (select a term)
intoGenPTGIR
Cancer3DPTGIR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600022   
Orphanet
MedgenPTGIR
Genetic Testing Registry PTGIR
NextProtP43119 [Medical]
TSGene5739
GENETestsPTGIR
Huge Navigator PTGIR [HugePedia]
snp3D : Map Gene to Disease5739
BioCentury BCIQPTGIR
ClinGenPTGIR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5739
Chemical/Pharm GKB GenePA291
Clinical trialPTGIR
Miscellaneous
canSAR (ICR)PTGIR (select the gene name)
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePTGIR
EVEXPTGIR
GoPubMedPTGIR
iHOPPTGIR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:33:25 CEST 2017

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