Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5739
MIM: 600022
HGNC: 9602
Ensembl: ENSG00000160013
Variants:
dbSNP: 5739
ClinVar: 5739
TCGA: ENSG00000160013
COSMIC: PTGIR
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA175 | GNAS | Gene | Pathway | associated | 20938371 | ||
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD | 17496729 | |
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 17496729 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32531060 | 2021 | Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia. | 13 |
| 32531060 | 2021 | Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia. | 13 |
| 26661245 | 2017 | Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-α in cerebral microvessels. | 12 |
| 28739266 | 2017 | Identification of α-helix 4 (α4) of Rab11a as a novel Rab11-binding domain (RBD): Interaction of Rab11a with the Prostacyclin Receptor. | 4 |
| 26661245 | 2017 | Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-α in cerebral microvessels. | 12 |
| 28739266 | 2017 | Identification of α-helix 4 (α4) of Rab11a as a novel Rab11-binding domain (RBD): Interaction of Rab11a with the Prostacyclin Receptor. | 4 |
| 26775637 | 2016 | IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin. | 17 |
| 26868296 | 2016 | Prostaglandin I2 Receptor Agonism Preserves β-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms. | 14 |
| 27365208 | 2016 | Regulated expression of the prostacyclin receptor (IP) gene by androgens within the vasculature: Combined role for androgens and serum cholesterol. | 3 |
| 26775637 | 2016 | IP-receptor and PPARs trigger the conversion of human white to brite adipocyte induced by carbaprostacyclin. | 17 |
| 26868296 | 2016 | Prostaglandin I2 Receptor Agonism Preserves β-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms. | 14 |
| 27365208 | 2016 | Regulated expression of the prostacyclin receptor (IP) gene by androgens within the vasculature: Combined role for androgens and serum cholesterol. | 3 |
| 25617843 | 2015 | Prostacyclin receptor expression on platelets of humans with type 2 diabetes is inversely correlated with hemoglobin A1c levels. | 5 |
| 25617843 | 2015 | Prostacyclin receptor expression on platelets of humans with type 2 diabetes is inversely correlated with hemoglobin A1c levels. | 5 |
| 24886841 | 2014 | High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function. | 5 |
Citation
Dessen P
PTGIR (prostaglandin I2 receptor)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/gene/50074/ptgir
