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PTP4A1 (protein tyrosine phosphatase type IVA, member 1)

Identity

Other namesHH72
PRL-1
PRL1
PTP(CAAX1)
PTPCAAX1
HGNC (Hugo) PTP4A1
LocusID (NCBI) 7803
Location 6q12
Location_base_pair Starts at 64281920 and ends at 64293489 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PTP4A1   9634
Entrez_Gene (NCBI)PTP4A1  7803  protein tyrosine phosphatase type IVA, member 1
Cards
GeneCards (Weizmann)PTP4A1
Ensembl (Hinxton)ENSG00000112245 [Gene_View]  chr6:64281920-64293489 [Contig_View]  PTP4A1 [Vega]
AceView (NCBI)PTP4A1
Genatlas (Paris)PTP4A1
SOURCE (Stanford)NM_003463
Genomic and cartography
GoldenPath (UCSC)PTP4A1  -  6q12   chr6:64281920-64293489 +  6q12   [Description]    (hg19-Feb_2009)
EnsemblPTP4A1 - 6q12 [CytoView]
Mapping of homologs : NCBIPTP4A1 [Mapview]
OMIM601585   
Gene and transcription
Genbank (Entrez)AB451314 AB451444 AJ420505 AK312526 BC023975
RefSeq transcript (SRS)NM_003463
RefSeq transcript (Entrez)NM_003463
RefSeq genomic (SRS)AC_000138 NC_000006 NC_018917 NT_007299 NW_001838985 NW_004078027
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NT_007299 NW_001838985 NW_004078027
Consensus coding sequences : CCDS (NCBI)PTP4A1
Cluster EST : UnigeneHs.227777 [ SRS ] Hs.227777 [ NCBI ]
CGAP (NCI)Hs.227777
Alternative Splicing : Fast-db (Paris)GSHG0025821
Alternative Splicing GalleryENSG00000112245
Gene ExpressionPTP4A1 [ NCBI-GEO ]   PTP4A1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ93096 (SRS) Q93096 (Uniprot)
NextProtQ93096
With graphics : InterProQ93096
Splice isoforms : SwissVarQ93096(Swissvar)
Domaine pattern : Prosite (SRS)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domains : Interpro (SRS)Tyr/Dual-specificity_Pase    Tyr_Pase_rcpt/non-rcpt   
Domains : Interpro (EBI)Tyr/Dual-specificity_Pase    Tyr_Pase_rcpt/non-rcpt   
Related proteins : CluSTrQ93096
Domain families : Pfam (SRS)Y_phosphatase (PF00102)   
Domain families : Pfam (Sanger)Y_phosphatase (PF00102)   
Domain families : Pfam (NCBI)pfam00102   
DMDM7803
Blocks (Seattle)Q93096
PDB (SRS)1RXD    1XM2   
PDB (PDBSum)1RXD    1XM2   
PDB (IMB)1RXD    1XM2   
PDB (RSDB)1RXD    1XM2   
Human Protein AtlasENSG00000112245
HPRD03349
IPIIPI00020164   IPI00513693   
Protein Interaction databases
DIP (DOE-UCLA)Q93096
IntAct (EBI)Q93096
FunCoupENSG00000112245
REACTOMEPTP4A1
Protein Interaction Database7803
BioGRIDPTP4A1
InParanoidQ93096
Interologous Interaction database Q93096
IntegromeDBPTP4A1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PTP4A1
SNP (GeneSNP Utah)PTP4A1
SNP : HGBasePTP4A1
Genetic variants : HAPMAPPTP4A1
Somatic Mutations in Cancer : COSMICPTP4A1 
CONAN: Copy Number AnalysisPTP4A1 
Mutations and Diseases : HGMDPTP4A1
OMIM601585   
GENETests601585   
Disease Genetic AssociationPTP4A1
Huge Navigator PTP4A1 [HugePedia]  PTP4A1 [HugeCancerGEM]
Genomic VariantsPTP4A1  PTP4A1 [DGVbeta]
snp3D : Map Gene to Disease7803
General knowledge
Homologs : HomoloGenePTP4A1
Homology/Alignments : Family Browser (UCSC)PTP4A1
Phylogenetic Trees/Animal Genes : TreeFamPTP4A1
Catalytic activity : Enzyme3.1.3.48 [ Enzyme-Expasy ]   3.1.3.48 [ Enzyme-SRS ]   3.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]   
Chemical/Protein Interactions : CTD7803
Chemical/Pharm GKB GenePA33977
Clinical trialPTP4A1
Cancer Resource (Charite)ENSG00000112245
Ontology : AmiGOprotein tyrosine phosphatase activity  nucleus  cytoplasm  early endosome  endoplasmic reticulum  spindle  cell cycle  multicellular organismal development  internal side of plasma membrane  positive regulation of cell migration  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  nucleus  cytoplasm  early endosome  endoplasmic reticulum  spindle  cell cycle  multicellular organismal development  internal side of plasma membrane  positive regulation of cell migration  
Other databases
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
PubGenePTP4A1
iHOPPTP4A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:28:12 CEST 2013
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