PTPRM (protein tyrosine phosphatase, receptor type, M)

Identity

Other names	MGC166994
	PTPRL1
	R-PTP-MU
	RPTPM
	RPTPU
	hR-PTPu
HGNC	PTPRM
Location	18p11.2
Location_base_pair	Starts at 7557314 and ends at 8396859 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PTPRM   9675
Entrez_Gene	PTPRM  5797  protein tyrosine phosphatase, receptor type, M
	Cards
GeneCards	PTPRM
Ensembl	ENSG00000173482 [Gene_View]  PTPRM [Vega]
Genatlas	PTPRM
	Genomic and cartography
GoldenPath	PTPRM  -  18p11.2   chr18:7557314-8396859 +  18p11.23   [Description]    (hg18-March_2006)
Ensembl	PTPRM - 18p11.23 [CytoView]
NCBI	Mapview
OMIM	176888 Disease map [OMIM]
HomoloGene	PTPRM
	Gene and transcription
Genbank	AA281524 [ ENTREZ ]
Genbank	AK294492 [ ENTREZ ]
Genbank	BC040543 [ ENTREZ ]
Genbank	BC051651 [ ENTREZ ]
Genbank	BC151842 [ ENTREZ ]
RefSeq	NM_001105244 [ SRS ]    NM_001105244 [ ENTREZ ]
RefSeq	NM_002845 [ SRS ]    NM_002845 [ ENTREZ ]
RefSeq	AC_000061 [ SRS ]    AC_000061 [ ENTREZ ]
RefSeq	AC_000150 [ SRS ]    AC_000150 [ ENTREZ ]
RefSeq	NC_000018 [ SRS ]    NC_000018 [ ENTREZ ]
RefSeq	NT_010859 [ SRS ]    NT_010859 [ ENTREZ ]
RefSeq	NW_001838461 [ SRS ]    NW_001838461 [ ENTREZ ]
RefSeq	NW_926940 [ SRS ]    NW_926940 [ ENTREZ ]
CCDS	PTPRM CCDS - NCBI
AceView	PTPRM AceView - NCBI
Unigene	Hs.49774 [ SRS ]    Hs.49774 [ NCBI ]
Fast-db	1016 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P28827 [ SRS]    P28827 [ EXPASY ]     P28827 [ INTERPRO ]     P28827 [ UNIPROT ] P28827 [ VarSplice FASTA ]
Prosite	PS50853 FN3 [ SRS ]    PS50853 FN3 [ Expasy ]
Prosite	PS50835 IG_LIKE [ SRS ]    PS50835 IG_LIKE [ Expasy ]
Prosite	PS00740 MAM_1 [ SRS ]    PS00740 MAM_1 [ Expasy ]
Prosite	PS50060 MAM_2 [ SRS ]    PS50060 MAM_2 [ Expasy ]
Prosite	PS00383 TYR_PHOSPHATASE_1 [ SRS ]    PS00383 TYR_PHOSPHATASE_1 [ Expasy ]
Prosite	PS50056 TYR_PHOSPHATASE_2 [ SRS ]    PS50056 TYR_PHOSPHATASE_2 [ Expasy ]
Prosite	PS50055 TYR_PHOSPHATASE_PTP [ SRS ]    PS50055 TYR_PHOSPHATASE_PTP [ Expasy ]
Interpro	IPR008957 Fibronectin_typ-III-like_fold [ SRS ]    IPR008957 Fibronectin_typ-III-like_fold [ EBI ]
Interpro	IPR003961 FN_III [ SRS ]    IPR003961 FN_III [ EBI ]
Interpro	IPR013151 Ig [ SRS ]    IPR013151 Ig [ EBI ]
Interpro	IPR007110 Ig-like [ SRS ]    IPR007110 Ig-like [ EBI ]
Interpro	IPR013783 Ig-like_fold [ SRS ]    IPR013783 Ig-like_fold [ EBI ]
Interpro	IPR003599 Ig_sub [ SRS ]    IPR003599 Ig_sub [ EBI ]
Interpro	IPR000998 MAM [ SRS ]    IPR000998 MAM [ EBI ]
Interpro	IPR000387 Tyr_Pase [ SRS ]    IPR000387 Tyr_Pase [ EBI ]
Interpro	IPR016130 Tyr_Pase_AS [ SRS ]    IPR016130 Tyr_Pase_AS [ EBI ]
Interpro	IPR000242 Tyr_Pase_rcpt/non-rcpt [ SRS ]    IPR000242 Tyr_Pase_rcpt/non-rcpt [ EBI ]
CluSTr	P28827
Pfam	PF00041 fn3 [ SRS ]    PF00041 fn3 [ Sanger ]    pfam00041 [ NCBI-CDD ]
Pfam	PF00047 ig [ SRS ]    PF00047 ig [ Sanger ]    pfam00047 [ NCBI-CDD ]
Pfam	PF00629 MAM [ SRS ]    PF00629 MAM [ Sanger ]    pfam00629 [ NCBI-CDD ]
Pfam	PF00102 Y_phosphatase [ SRS ]    PF00102 Y_phosphatase [ Sanger ]    pfam00102 [ NCBI-CDD ]
Smart	SM00060 FN3 [EMBL]
Smart	SM00409 IG [EMBL]
Smart	SM00137 MAM [EMBL]
Smart	SM00194 PTPc [EMBL]
Blocks	P28827
PDB	1RPM [ SRS ]    1RPM [ PdbSum ],   1RPM [ IMB ]   1RPM [ RSDB ]
PDB	2C9A [ SRS ]    2C9A [ PdbSum ],   2C9A [ IMB ]   2C9A [ RSDB ]
PDB	2V5Y [ SRS ]    2V5Y [ PdbSum ],   2V5Y [ IMB ]   2V5Y [ RSDB ]
HPRD	01479
	Protein Interaction databases
DIP	P28827
IntAct	P28827
	Polymorphism : SNP, mutations, diseases
OMIM	176888    [ map ]
GENETests	176888
SNP	PTPRM [dbSNP-NCBI]
SNP	NM_001105244 [SNP-NCI]
SNP	NM_002845 [SNP-NCI]
SNP	PTPRM [GeneSNPs - Utah]  PTPRM] [HGBASE - SRS]
HAPMAP	PTPRM [HAPMAP]
COSMIC	PTPRM [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PTPRM
Genetic Association	PTPRM
CDC HuGE	PTPRM
	General knowledge
Family Browser	PTPRM [UCSC Family Browser]
SOURCE	NM_001105244
SOURCE	NM_002845
SMD	Hs.49774
SAGE	Hs.49774
Enzyme	3.1.3.48 [ Enzyme-Expasy ]   3.1.3.48 [ Enzyme-SRS ]   3.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]
GO	protein tyrosine phosphatase activity [Amigo]  protein tyrosine phosphatase activity
GO	receptor activity [Amigo]  receptor activity
GO	transmembrane receptor protein tyrosine phosphatase activity [Amigo]  transmembrane receptor protein tyrosine phosphatase activity
GO	protein binding [Amigo]  protein binding
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	protein amino acid dephosphorylation [Amigo]  protein amino acid dephosphorylation
GO	protein amino acid dephosphorylation [Amigo]  protein amino acid dephosphorylation
GO	cell adhesion [Amigo]  cell adhesion
GO	membrane [Amigo]  membrane
GO	hydrolase activity [Amigo]  hydrolase activity
GO	phosphatase activity [Amigo]  phosphatase activity
KEGG	Cell adhesion molecules (CAMs)
KEGG	Adherens junction
PubGene	PTPRM
TreeFam	PTPRM
CTD	5797 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PTPRM Related clones (RZPD - Berlin)
	PubMed
PubMed	24 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:06:43 2008