PXK (PX domain containing serine/threonine kinase like)

2006-10-01  

Identity

HGNC
LOCATION
3p14.3
LOCUSID
ALIAS
MONAKA,SLOB
FUSION GENES

Other Information

Locus ID:

NCBI: 54899
MIM: 611450
HGNC: 23326
Ensembl: ENSG00000168297

Variants:

dbSNP: 54899
ClinVar: 54899
TCGA: ENSG00000168297
COSMIC: PXK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168297ENST00000302779W5RWE6
ENSG00000168297ENST00000356151Q7Z7A4
ENSG00000168297ENST00000383715H7BYG4
ENSG00000168297ENST00000383716Q7Z7A4
ENSG00000168297ENST00000459676U3KQS4
ENSG00000168297ENST00000463280E9PD56
ENSG00000168297ENST00000468776F8WAW8
ENSG00000168297ENST00000477308F8WDF7
ENSG00000168297ENST00000479134H7C4V0
ENSG00000168297ENST00000479241A0A0C4DG95
ENSG00000168297ENST00000484288Q7Z7A4
ENSG00000168297ENST00000491164C9IYJ2
ENSG00000168297ENST00000493474H7C529
ENSG00000168297ENST00000495557H7C4W2

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
182044462008Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.488
182044462008Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.488
204538422010Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.480
152896072004The mouse kinome: discovery and comparative genomics of all mouse protein kinases.100
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
237409372013A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.36
208810112011Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.31
208485682010Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.23
192255262009Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese.22
209628502011A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles.21

Citation

Dessen P

PXK (PX domain containing serine/threonine kinase like)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43440/pxk