Atlas of Genetics and Cytogenetics in Oncology and Haematology


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QKI (QKI, KH domain containing RNA binding)

Identity

Alias_namesquaking homolog
Alias_symbol (synonym)QK3
Other aliasHqk
QK
QK1
hqkI
HGNC (Hugo) QKI
LocusID (NCBI) 9444
Atlas_Id 46703
Location 6q26  [Link to chromosome band 6q26]
Location_base_pair Starts at 163414643 and ends at 163578596 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACAP2 (3q29) / QKI (6q26)FREM2 (13q13.3) / QKI (6q26)HLA-DPA1 (6p21.32) / QKI (6q26)
NEK10 (3p24.1) / QKI (6q26)PCDHGC3 (5q31.3) / QKI (6q26)PRMT7 (16q22.1) / QKI (6q26)
QKI (6q26) / NTRK2 (9q21.33)QKI (6q26) / PACRG (6q26)QKI (6q26) / QKI (6q26)
QKI (6q26) / RAF1 (3p25.2)QKI (6q26) / ZNF214 (11p15.4)WDR27 (6q27) / QKI (6q26)
QKI 6q26 / NTRK2 9q21.33PCDHGC3 5q31.3 / QKI 6q26QKI 6q26 / PACRG 6q26
QKI 6q26 / ZNF214 11p15.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)QKI   21100
Cards
Entrez_Gene (NCBI)QKI  9444  QKI, KH domain containing RNA binding
AliasesHqk; QK; QK1; QK3; 
hqkI
GeneCards (Weizmann)QKI
Ensembl hg19 (Hinxton)ENSG00000112531 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112531 [Gene_View]  chr6:163414643-163578596 [Contig_View]  QKI [Vega]
ICGC DataPortalENSG00000112531
TCGA cBioPortalQKI
AceView (NCBI)QKI
Genatlas (Paris)QKI
WikiGenes9444
SOURCE (Princeton)QKI
Genetics Home Reference (NIH)QKI
Genomic and cartography
GoldenPath hg38 (UCSC)QKI  -     chr6:163414643-163578596 +  6q26   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)QKI  -     6q26   [Description]    (hg19-Feb_2009)
EnsemblQKI - 6q26 [CytoView hg19]  QKI - 6q26 [CytoView hg38]
Mapping of homologs : NCBIQKI [Mapview hg19]  QKI [Mapview hg38]
OMIM609590   
Gene and transcription
Genbank (Entrez)AB067798 AB067799 AB067800 AB067801 AF142422
RefSeq transcript (Entrez)NM_001301085 NM_006775 NM_206853 NM_206854 NM_206855
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)QKI
Cluster EST : UnigeneHs.510324 [ NCBI ]
CGAP (NCI)Hs.510324
Alternative Splicing GalleryENSG00000112531
Gene ExpressionQKI [ NCBI-GEO ]   QKI [ EBI - ARRAY_EXPRESS ]   QKI [ SEEK ]   QKI [ MEM ]
Gene Expression Viewer (FireBrowse)QKI [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9444
GTEX Portal (Tissue expression)QKI
Human Protein AtlasENSG00000112531-QKI [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PU8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PU8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PU8
Splice isoforms : SwissVarQ96PU8
PhosPhoSitePlusQ96PU8
Domains : Interpro (EBI)KH_dom    KH_dom_type_1    Quaking_NLS    STAR_dimer   
Domain families : Pfam (Sanger)KH_1 (PF00013)    Quaking_NLS (PF16551)    STAR_dimer (PF16544)   
Domain families : Pfam (NCBI)pfam00013    pfam16551    pfam16544   
Domain families : Smart (EMBL)KH (SM00322)  
Conserved Domain (NCBI)QKI
DMDM Disease mutations9444
Blocks (Seattle)QKI
PDB (SRS)4JVH   
PDB (PDBSum)4JVH   
PDB (IMB)4JVH   
PDB (RSDB)4JVH   
Structural Biology KnowledgeBase4JVH   
SCOP (Structural Classification of Proteins)4JVH   
CATH (Classification of proteins structures)4JVH   
SuperfamilyQ96PU8
Human Protein Atlas [tissue]ENSG00000112531-QKI [tissue]
Peptide AtlasQ96PU8
HPRD06691
IPIIPI00514277   IPI00736672   IPI00759828   IPI00385562   IPI00749287   IPI00942653   IPI00383166   IPI01015802   IPI01010211   IPI01009757   IPI01015412   IPI01014915   IPI01009310   IPI01015844   IPI01013590   
Protein Interaction databases
DIP (DOE-UCLA)Q96PU8
IntAct (EBI)Q96PU8
FunCoupENSG00000112531
BioGRIDQKI
STRING (EMBL)QKI
ZODIACQKI
Ontologies - Pathways
QuickGOQ96PU8
Ontology : AmiGOvasculogenesis  RNA binding  mRNA binding  protein binding  nucleus  cytoplasm  mRNA processing  spermatid development  RNA splicing  positive regulation of gene expression  SH3 domain binding  myelination  muscle cell differentiation  long-chain fatty acid biosynthetic process  mRNA transport  3'-UTR-mediated mRNA destabilization  
Ontology : EGO-EBIvasculogenesis  RNA binding  mRNA binding  protein binding  nucleus  cytoplasm  mRNA processing  spermatid development  RNA splicing  positive regulation of gene expression  SH3 domain binding  myelination  muscle cell differentiation  long-chain fatty acid biosynthetic process  mRNA transport  3'-UTR-mediated mRNA destabilization  
NDEx NetworkQKI
Atlas of Cancer Signalling NetworkQKI
Wikipedia pathwaysQKI
Orthology - Evolution
OrthoDB9444
GeneTree (enSembl)ENSG00000112531
Phylogenetic Trees/Animal Genes : TreeFamQKI
HOVERGENQ96PU8
HOGENOMQ96PU8
Homologs : HomoloGeneQKI
Homology/Alignments : Family Browser (UCSC)QKI
Gene fusions - Rearrangements
Fusion : MitelmanPCDHGC3/QKI [5q31.3/6q26]  [t(5;6)(q31;q26)]  
Fusion : MitelmanQKI/NTRK2 [6q26/9q21.33]  [t(6;9)(q26;q21)]  
Fusion : MitelmanQKI/RAF1 [6q26/3p25.2]  [t(3;6)(p25;q26)]  
Fusion : MitelmanQKI/ZNF214 [6q26/11p15.4]  [t(6;11)(q26;p15)]  
Fusion: TCGA_MDACCPCDHGC3 5q31.3 QKI 6q26 GBM
Fusion: TCGA_MDACCQKI 6q26 PACRG 6q26 BRCA LUAD LUSC OV
Fusion: TCGA_MDACCQKI 6q26 ZNF214 11p15.4 BRCA
Tumor Fusion PortalQKI
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerQKI [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)QKI
dbVarQKI
ClinVarQKI
1000_GenomesQKI 
Exome Variant ServerQKI
ExAC (Exome Aggregation Consortium)ENSG00000112531
GNOMAD BrowserENSG00000112531
Genetic variants : HAPMAP9444
Genomic Variants (DGV)QKI [DGVbeta]
DECIPHERQKI [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisQKI 
Mutations
ICGC Data PortalQKI 
TCGA Data PortalQKI 
Broad Tumor PortalQKI
OASIS PortalQKI [ Somatic mutations - Copy number]
Cancer Gene: CensusQKI 
Somatic Mutations in Cancer : COSMICQKI  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDQKI
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch QKI
DgiDB (Drug Gene Interaction Database)QKI
DoCM (Curated mutations)QKI (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)QKI (select a term)
intoGenQKI
Cancer3DQKI(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609590   
Orphanet19674   
DisGeNETQKI
MedgenQKI
Genetic Testing Registry QKI
NextProtQ96PU8 [Medical]
TSGene9444
GENETestsQKI
Target ValidationQKI
Huge Navigator QKI [HugePedia]
snp3D : Map Gene to Disease9444
BioCentury BCIQQKI
ClinGenQKI
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9444
Chemical/Pharm GKB GenePA134912180
Clinical trialQKI
Miscellaneous
canSAR (ICR)QKI (select the gene name)
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineQKI
EVEXQKI
GoPubMedQKI
iHOPQKI
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:31:10 CET 2017

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