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REC8 (REC8 meiotic recombination protein)

Identity

Alias_namesREC8L1
REC8-like 1 (yeast)
REC8 homolog (yeast)
Alias_symbol (synonym)Rec8p
kleisin-alpha
Other aliasHR21spB
HGNC (Hugo) REC8
LocusID (NCBI) 9985
Atlas_Id 51164
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24172025 and ends at 24180257 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SORCS3 (10q25.1) / REC8 (14q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)REC8   16879
Cards
Entrez_Gene (NCBI)REC8  9985  REC8 meiotic recombination protein
AliasesHR21spB; REC8L1; Rec8p
GeneCards (Weizmann)REC8
Ensembl hg19 (Hinxton)ENSG00000100918 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100918 [Gene_View]  chr14:24172025-24180257 [Contig_View]  REC8 [Vega]
ICGC DataPortalENSG00000100918
TCGA cBioPortalREC8
AceView (NCBI)REC8
Genatlas (Paris)REC8
WikiGenes9985
SOURCE (Princeton)REC8
Genetics Home Reference (NIH)REC8
Genomic and cartography
GoldenPath hg38 (UCSC)REC8  -     chr14:24172025-24180257 +  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)REC8  -     14q12   [Description]    (hg19-Feb_2009)
EnsemblREC8 - 14q12 [CytoView hg19]  REC8 - 14q12 [CytoView hg38]
Mapping of homologs : NCBIREC8 [Mapview hg19]  REC8 [Mapview hg38]
OMIM608193   
Gene and transcription
Genbank (Entrez)AA496891 AF006264 AK001435 AK291191 AL832973
RefSeq transcript (Entrez)NM_001048205 NM_005132
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)REC8
Cluster EST : UnigeneHs.419259 [ NCBI ]
CGAP (NCI)Hs.419259
Alternative Splicing GalleryENSG00000100918
Gene ExpressionREC8 [ NCBI-GEO ]   REC8 [ EBI - ARRAY_EXPRESS ]   REC8 [ SEEK ]   REC8 [ MEM ]
Gene Expression Viewer (FireBrowse)REC8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9985
GTEX Portal (Tissue expression)REC8
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95072   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95072  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95072
Splice isoforms : SwissVarO95072
PhosPhoSitePlusO95072
Domains : Interpro (EBI)Rad21/Rec8_C    Rad21/Rec8_C_eu    Rad21_Rec8_N    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Rad21_Rec8 (PF04824)    Rad21_Rec8_N (PF04825)   
Domain families : Pfam (NCBI)pfam04824    pfam04825   
Conserved Domain (NCBI)REC8
DMDM Disease mutations9985
Blocks (Seattle)REC8
SuperfamilyO95072
Human Protein AtlasENSG00000100918
Peptide AtlasO95072
HPRD09739
IPIIPI00293487   IPI00937443   
Protein Interaction databases
DIP (DOE-UCLA)O95072
IntAct (EBI)O95072
FunCoupENSG00000100918
BioGRIDREC8
STRING (EMBL)REC8
ZODIACREC8
Ontologies - Pathways
QuickGOO95072
Ontology : AmiGOdouble-strand break repair via homologous recombination  condensed nuclear chromosome kinetochore  nuclear cohesin complex  lateral element  oocyte maturation  male germ cell nucleus  chromatin binding  nucleus  double-strand break repair  sister chromatid cohesion  synaptonemal complex assembly  reciprocal meiotic recombination  male meiosis I  spermatogenesis  spermatid development  fertilization  meiotic cohesin complex  nuclear meiotic cohesin complex  meiotic cell cycle  seminiferous tubule development  
Ontology : EGO-EBIdouble-strand break repair via homologous recombination  condensed nuclear chromosome kinetochore  nuclear cohesin complex  lateral element  oocyte maturation  male germ cell nucleus  chromatin binding  nucleus  double-strand break repair  sister chromatid cohesion  synaptonemal complex assembly  reciprocal meiotic recombination  male meiosis I  spermatogenesis  spermatid development  fertilization  meiotic cohesin complex  nuclear meiotic cohesin complex  meiotic cell cycle  seminiferous tubule development  
Pathways : KEGGOocyte meiosis   
NDEx NetworkREC8
Atlas of Cancer Signalling NetworkREC8
Wikipedia pathwaysREC8
Orthology - Evolution
OrthoDB9985
GeneTree (enSembl)ENSG00000100918
Phylogenetic Trees/Animal Genes : TreeFamREC8
HOVERGENO95072
HOGENOMO95072
Homologs : HomoloGeneREC8
Homology/Alignments : Family Browser (UCSC)REC8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerREC8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)REC8
dbVarREC8
ClinVarREC8
1000_GenomesREC8 
Exome Variant ServerREC8
ExAC (Exome Aggregation Consortium)REC8 (select the gene name)
Genetic variants : HAPMAP9985
Genomic Variants (DGV)REC8 [DGVbeta]
DECIPHERREC8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisREC8 
Mutations
ICGC Data PortalREC8 
TCGA Data PortalREC8 
Broad Tumor PortalREC8
OASIS PortalREC8 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDREC8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch REC8
DgiDB (Drug Gene Interaction Database)REC8
DoCM (Curated mutations)REC8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)REC8 (select a term)
intoGenREC8
Cancer3DREC8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608193   
Orphanet
MedgenREC8
Genetic Testing Registry REC8
NextProtO95072 [Medical]
TSGene9985
GENETestsREC8
Target ValidationREC8
Huge Navigator REC8 [HugePedia]
snp3D : Map Gene to Disease9985
BioCentury BCIQREC8
ClinGenREC8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9985
Chemical/Pharm GKB GenePA162401009
Clinical trialREC8
Miscellaneous
canSAR (ICR)REC8 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineREC8
EVEXREC8
GoPubMedREC8
iHOPREC8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:52:56 CEST 2017

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