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REV1 (REV1, DNA directed polymerase)

Identity

Alias_namesREV1L
REV1 (yeast homolog)- like
REV1-like (yeast)
REV1 homolog (S. cerevisiae)
REV1, polymerase (DNA directed)
Other aliasAIBP80
HGNC (Hugo) REV1
LocusID (NCBI) 51455
Atlas_Id 42085
Location 2q11.2  [Link to chromosome band 2q11]
Location_base_pair Starts at 99400475 and ends at 99490056 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
REV1 (2q11.2) / EIF5 (14q32.32)REV1 (2q11.2) / REV1 (2q11.2)REV1 (2q11.2) / SIAE (11q24.2)
REV1 (2q11.2) / SUPT3H (6p21.1)REV1 (2q11.2) / ZNF385A (12q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)REV1   14060
Cards
Entrez_Gene (NCBI)REV1  51455  REV1, DNA directed polymerase
AliasesAIBP80; REV1L
GeneCards (Weizmann)REV1
Ensembl hg19 (Hinxton)ENSG00000135945 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135945 [Gene_View]  ENSG00000135945 [Sequence]  chr2:99400475-99490056 [Contig_View]  REV1 [Vega]
ICGC DataPortalENSG00000135945
TCGA cBioPortalREV1
AceView (NCBI)REV1
Genatlas (Paris)REV1
WikiGenes51455
SOURCE (Princeton)REV1
Genetics Home Reference (NIH)REV1
Genomic and cartography
GoldenPath hg38 (UCSC)REV1  -     chr2:99400475-99490056 -  2q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)REV1  -     2q11.2   [Description]    (hg19-Feb_2009)
EnsemblREV1 - 2q11.2 [CytoView hg19]  REV1 - 2q11.2 [CytoView hg38]
Mapping of homologs : NCBIREV1 [Mapview hg19]  REV1 [Mapview hg38]
OMIM606134   
Gene and transcription
Genbank (Entrez)AB047646 AF151538 AF206019 AF357886 AJ131720
RefSeq transcript (Entrez)NM_001037872 NM_001321454 NM_001321455 NM_001321458 NM_001321459 NM_001321460 NM_016316
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)REV1
Cluster EST : UnigeneHs.443077 [ NCBI ]
CGAP (NCI)Hs.443077
Alternative Splicing GalleryENSG00000135945
Gene ExpressionREV1 [ NCBI-GEO ]   REV1 [ EBI - ARRAY_EXPRESS ]   REV1 [ SEEK ]   REV1 [ MEM ]
Gene Expression Viewer (FireBrowse)REV1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51455
GTEX Portal (Tissue expression)REV1
Human Protein AtlasENSG00000135945-REV1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBZ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBZ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBZ9
Splice isoforms : SwissVarQ9UBZ9
Catalytic activity : Enzyme2.7.7.- [ Enzyme-Expasy ]   2.7.7.-2.7.7.- [ IntEnz-EBI ]   2.7.7.- [ BRENDA ]   2.7.7.- [ KEGG ]   
PhosPhoSitePlusQ9UBZ9
Domaine pattern : Prosite (Expaxy)BRCT (PS50172)    UMUC (PS50173)   
Domains : Interpro (EBI)BRCT_dom    DNA_pol_Y-fam_little_finger    DUF4414    REV1    Rev1_C    UmuC   
Domain families : Pfam (Sanger)BRCT_2 (PF16589)    DUF4414 (PF14377)    IMS (PF00817)    IMS_C (PF11799)    REV1_C (PF16727)   
Domain families : Pfam (NCBI)pfam16589    pfam14377    pfam00817    pfam11799    pfam16727   
Domain families : Smart (EMBL)BRCT (SM00292)  
Conserved Domain (NCBI)REV1
DMDM Disease mutations51455
Blocks (Seattle)REV1
PDB (SRS)2EBW    2LSI    2LSK    2LSY    2N1G    3GQC    3VU7    4BA9    4EXT    4GK0    4GK5   
PDB (PDBSum)2EBW    2LSI    2LSK    2LSY    2N1G    3GQC    3VU7    4BA9    4EXT    4GK0    4GK5   
PDB (IMB)2EBW    2LSI    2LSK    2LSY    2N1G    3GQC    3VU7    4BA9    4EXT    4GK0    4GK5   
PDB (RSDB)2EBW    2LSI    2LSK    2LSY    2N1G    3GQC    3VU7    4BA9    4EXT    4GK0    4GK5   
Structural Biology KnowledgeBase2EBW    2LSI    2LSK    2LSY    2N1G    3GQC    3VU7    4BA9    4EXT    4GK0    4GK5   
SCOP (Structural Classification of Proteins)2EBW    2LSI    2LSK    2LSY    2N1G    3GQC    3VU7    4BA9    4EXT    4GK0    4GK5   
CATH (Classification of proteins structures)2EBW    2LSI    2LSK    2LSY    2N1G    3GQC    3VU7    4BA9    4EXT    4GK0    4GK5   
SuperfamilyQ9UBZ9
Human Protein Atlas [tissue]ENSG00000135945-REV1 [tissue]
Peptide AtlasQ9UBZ9
HPRD16202
IPIIPI00008816   IPI00552928   IPI00552936   IPI00916059   IPI00917273   IPI00917397   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBZ9
IntAct (EBI)Q9UBZ9
FunCoupENSG00000135945
BioGRIDREV1
STRING (EMBL)REV1
ZODIACREV1
Ontologies - Pathways
QuickGOQ9UBZ9
Ontology : AmiGOdamaged DNA binding  protein binding  nucleoplasm  DNA replication  response to UV  deoxycytidyl transferase activity  translesion synthesis  error-prone translesion synthesis  metal ion binding  
Ontology : EGO-EBIdamaged DNA binding  protein binding  nucleoplasm  DNA replication  response to UV  deoxycytidyl transferase activity  translesion synthesis  error-prone translesion synthesis  metal ion binding  
Pathways : KEGGDNA polymerase   
NDEx NetworkREV1
Atlas of Cancer Signalling NetworkREV1
Wikipedia pathwaysREV1
Orthology - Evolution
OrthoDB51455
GeneTree (enSembl)ENSG00000135945
Phylogenetic Trees/Animal Genes : TreeFamREV1
HOVERGENQ9UBZ9
HOGENOMQ9UBZ9
Homologs : HomoloGeneREV1
Homology/Alignments : Family Browser (UCSC)REV1
Gene fusions - Rearrangements
Fusion : QuiverREV1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerREV1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)REV1
dbVarREV1
ClinVarREV1
1000_GenomesREV1 
Exome Variant ServerREV1
ExAC (Exome Aggregation Consortium)ENSG00000135945
GNOMAD BrowserENSG00000135945
Genetic variants : HAPMAP51455
Genomic Variants (DGV)REV1 [DGVbeta]
DECIPHERREV1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisREV1 
Mutations
ICGC Data PortalREV1 
TCGA Data PortalREV1 
Broad Tumor PortalREV1
OASIS PortalREV1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICREV1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDREV1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch REV1
DgiDB (Drug Gene Interaction Database)REV1
DoCM (Curated mutations)REV1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)REV1 (select a term)
intoGenREV1
Cancer3DREV1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606134   
Orphanet
DisGeNETREV1
MedgenREV1
Genetic Testing Registry REV1
NextProtQ9UBZ9 [Medical]
TSGene51455
GENETestsREV1
Target ValidationREV1
Huge Navigator REV1 [HugePedia]
snp3D : Map Gene to Disease51455
BioCentury BCIQREV1
ClinGenREV1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51455
Chemical/Pharm GKB GenePA162401120
Clinical trialREV1
Miscellaneous
canSAR (ICR)REV1 (select the gene name)
Probes
Litterature
PubMed76 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineREV1
EVEXREV1
GoPubMedREV1
iHOPREV1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:46:52 CEST 2018

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